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FOLR2 Products

(Folate Receptor 2 (Fetal) (FOLR2))
The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured FOLR2 Categories

FOLR2 Antibodies

High quality antibodies with extensive validation data.

FOLR2 ELISA Kits

Reliable ELISA kits for a wide range of species.

FOLR2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended FOLR2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, FACS, IHC (p)
Validations
  • (1)
  • (7)
Cat. No. ABIN651222
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IHC (p), IF, ICC
Validations
  • (1)
  • (2)
Cat. No. ABIN2856196
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
Cat. No. ABIN7152990
Quantity 100 μg
Datasheet Datasheet

Recommended FOLR2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955946
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN5510703
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN5526866
Quantity 96 tests
Datasheet Datasheet

Recommended FOLR2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274664
Quantity 100 μg
Datasheet Datasheet
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274663
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7274670
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our FOLR2 products

Meredith, MacNeil, Trasler, Baltz: "Growing Mouse Oocytes Transiently Activate Folate Transport via Folate Receptors As They Approach Full Size." in: Biology of reproduction, Vol. 94, Issue 6, pp. 125, (2017) (PubMed).

Puligujja, McMillan, Kendrick, Li, Balkundi, Smith, Veerubhotla, Edagwa, Kabanov, Bronich, Gendelman, Liu: "Macrophage folate receptor-targeted antiretroviral therapy facilitates drug entry, retention, antiretroviral activities and biodistribution for reduction of human immunodeficiency virus infections." in: Nanomedicine : nanotechnology, biology, and medicine, Vol. 9, Issue 8, pp. 1263-73, (2013) (PubMed).

Sadasivan, Cedeno, Rothenberg: "Characterization of the gene encoding a folate-binding protein expressed in human placenta. Identification of promoter activity in a G-rich SP1 site linked with the tandemly repeated GGAAG motif for the ets encoded GA-binding protein." in: The Journal of biological chemistry, Vol. 269, Issue 7, pp. 4725-35, (1994) (PubMed).

Page, Owen, Price, Elwood: "Expression of the human placental folate receptor transcript is regulated in human tissues. Organization and full nucleotide sequence of the gene." in: Journal of molecular biology, Vol. 229, Issue 4, pp. 1175-83, (1993) (PubMed).

Ratnam, Marquardt, Duhring, Freisheim: "Homologous membrane folate binding proteins in human placenta: cloning and sequence of a cDNA." in: Biochemistry, Vol. 28, Issue 20, pp. 8249-54, (1990) (PubMed).

Synonyms and alternative names related to FOLR2

folate receptor 1 (FOLR1), folate receptor beta (FOLR2), folate receptor 2 (fetal) (FOLR2), folate receptor 2 (fetal) (Folr2), folate receptor beta (Folr2), BETA-HFR, FBP, FBP/PL-1, FBP2, Folbp-2, Folbp2, FOLR2, FR-BETA, FR-P3

Protein level used designations for FOLR2

  • folate receptor 2 (fetal)
  • folate receptor beta
  • folate receptor, beta
  • folate receptor, fetal/placental
  • folate-binding protein, fetal/placental
  • placental folate-binding protein
  • FR-beta
  • folate binding protein 2
  • folate-binding protein 2
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