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Forkhead Box A1 (FOXA1) (AA 270-299), (Middle Region) antibody

Details for Product No. ABIN952360
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Antigen
Synonyms
HNF3A, TCF3A, Hnf3a, Tcf3a, Hnf-3a, Tcf-3a, fkd7, forkhead-7, HNF-3a, HNF3-alpha, HNF3alpha, fkh2, foxa1, hnf3a, tFoxA1, tcf3a, FoxA4a, XFD-1, fkh1, pintallavis, xfkh1, xkfh-1, xfkh2, fkh, FOXA1, Ci-f ... show more
HNF3A, TCF3A, Hnf3a, Tcf3a, Hnf-3a, Tcf-3a, fkd7, forkhead-7, HNF-3a, HNF3-alpha, HNF3alpha, fkh2, foxa1, hnf3a, tFoxA1, tcf3a, FoxA4a, XFD-1, fkh1, pintallavis, xfkh1, xkfh-1, xfkh2, fkh, FOXA1, Ci-fkh, foxa3, Foxa1 show less
Epitope
AA 270-299, Middle Region
(25), (8), (7), (7), (6), (4), (3), (2), (2), (2), (1), (1), (1), (1)
Reactivity
Human
(86), (14), (10), (6), (3), (3), (3), (2), (1)
Host
Rabbit
(46), (31), (10)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(67), (45), (43), (17), (6), (5), (3), (2), (1)
Pubmed 5 references available
Quantity 0.4 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Catalog No. ABIN952360
357.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen KLH conjugated synthetic peptide between 270-299 amino acids from the Central region of Human FOXA1 / TCF3A
Specificity This antibody recognizes Human FOXA1 / TCF3A (Center).
Purification Protein A column, followed by peptide affinity purification
Alternative Name FOXA1 / TCF3A
Background This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver.
Alternate names: Forkhead box protein A1, HNF-3-alpha, HNF-3A, HNF3A, Hepatocyte nuclear factor 3-alpha, TCF-3A, Transcription factor 3A
Molecular Weight 49148 Da
Gene ID 3169
NCBI Accession NP_004487
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09% (w/v) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Song, Washington, Crawford: "Loss of FOXA1/2 is essential for the epithelial-to-mesenchymal transition in pancreatic cancer." in: Cancer research, Vol. 70, Issue 5, pp. 2115-25, 2010 (PubMed).

Bernardo, Lozada, Miedler et al.: "FOXA1 is an essential determinant of ERalpha expression and mammary ductal morphogenesis." in: Development (Cambridge, England), Vol. 137, Issue 12, pp. 2045-54, 2010 (PubMed).

Zhang, Liang, Li et al.: "CCCTC-binding factor acts upstream of FOXA1 and demarcates the genomic response to estrogen." in: The Journal of biological chemistry, Vol. 285, Issue 37, pp. 28604-13, 2010 (PubMed).

Hu, Gardner-Stephen, Severi et al.: "A novel polymorphism in a forkhead box A1 (FOXA1) binding site of the human UDP glucuronosyltransferase 2B17 gene modulates promoter activity and is associated with altered levels of circulating androstane-3α,17β-diol glucuronide." in: Molecular pharmacology, Vol. 78, Issue 4, pp. 714-22, 2010 (PubMed).

Liu, Niu, Wang et al.: "[Diagnostic and prognostic significance of FOXA1 expression in molecular subtypes of breast invasive ductal carcinomas]." in: Zhonghua yi xue za zhi, Vol. 90, Issue 20, pp. 1403-7, 2010 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN952360
357.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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