Growth Arrest and DNA-Damage-Inducible, gamma (GADD45G) (AA 1-30), (N-Term) antibody

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Synonyms zgc:77806, GADD45G, XGadd45-gamma, cr6, ddit2, gadd45gamma, grp17, xgadd45g, AI327420, C86281, CR6, DDIT2, OIG37, GADD45gamma, GRP17
N-Term, AA 1-30
(16), (16), (15), (12), (6), (5), (4), (4), (2), (1), (1), (1), (1), (1), (1)
(134), (25), (22), (2), (2), (2), (2), (1), (1)
(61), (42), (30), (3)
(5), (5), (5), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1)
Enzyme Immunoassay (EIA), Western Blotting (WB)
(88), (51), (22), (11), (10), (10), (4), (3), (2), (1), (1), (1)
Pubmed 5 references available
Quantity 0.4 mL
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Request Want additional data for this product?

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Immunogen KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human GADD45G
Isotype Ig
Specificity This antibody recognizes Human GADD45G (N-term).
Purification Protein A column, followed by peptide affinity purification
Alternative Name GADD45G (GADD45G Antibody Abstract)
Background This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta.Synonyms: CR6, Cytokine-responsive protein CR6, DDIT2, DNA-damage-inducible transcript 2, Growth arrest and DNA-damage-inducible protein GADD45 gamma
Molecular Weight 17121 Da
Gene ID 10912
NCBI Accession NP_006696
Research Area DNA/RNA, Apoptosis/Necrosis
Pathways Cell Division Cycle
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Flores, Burnstein: "GADD45gamma: a new vitamin D-regulated gene that is antiproliferative in prostate cancer cells." in: Endocrinology, Vol. 151, Issue 10, pp. 4654-64, 2010 (PubMed).

Zhang, Li, Shao et al.: "Semi-quantitative detection of GADD45-gamma methylation levels in gastric, colorectal and pancreatic cancers using methylation-sensitive high-resolution melting analysis." in: Journal of cancer research and clinical oncology, Vol. 136, Issue 8, pp. 1267-73, 2010 (PubMed).

Yu, Cho, Park et al.: "Urinary GADD45gamma expression is associated with progression of lgA nephropathy." in: American journal of nephrology, Vol. 30, Issue 2, pp. 135-9, 2009 (PubMed).

Palmieri, Wilson, Iversen et al.: "Polymorphism in the IL18 gene and epithelial ovarian cancer in non-Hispanic white women. ..." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 17, Issue 12, pp. 3567-72, 2008 (PubMed).

Zhu, Shao, Xu et al.: "Gadd45-alpha and Gadd45-gamma utilize p38 and JNK signaling pathways to induce cell cycle G2/M arrest in Hep-G2 hepatoma cells." in: Molecular biology reports, Vol. 36, Issue 8, pp. 2075-85, 2009 (PubMed).

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Catalog No. ABIN952425
$ 357.50
Plus shipping costs $45.00
0.4 mL
$ 357.50

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