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GADD45G antibody (Growth Arrest and DNA-Damage-Inducible, gamma) (N-Term)

Details for Product anti-GADD45G Antibody No. ABIN952425, Supplier: Log in to see
Antigen
  • zgc:77806
  • GADD45G
  • XGadd45-gamma
  • cr6
  • ddit2
  • gadd45gamma
  • grp17
  • xgadd45g
  • AI327420
  • C86281
  • CR6
  • DDIT2
  • OIG37
  • GADD45gamma
  • GRP17
Alternatives
anti-Human GADD45G antibody for Enzyme Immunoassay
Epitope
N-Term, AA 1-30
17
17
17
13
10
10
9
5
4
2
2
1
1
1
1
Reactivity
Human
140
26
23
2
2
2
2
1
1
Host
Rabbit
62
50
28
2
Clonality
Polyclonal
Conjugate
This GADD45G antibody is un-conjugated
6
6
6
4
4
4
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
90
56
24
11
11
11
4
2
1
1
1
Supplier
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Immunogen KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human GADD45G
Isotype Ig
Specificity This antibody recognizes Human GADD45G (N-term).
Purification Protein A column, followed by peptide affinity purification
Alternative Name GADD45G (GADD45G Antibody Abstract)
Background This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta.Synonyms: CR6, Cytokine-responsive protein CR6, DDIT2, DNA-damage-inducible transcript 2, Growth arrest and DNA-damage-inducible protein GADD45 gamma
Molecular Weight 17121 Da
Gene ID 10912
NCBI Accession NP_006696
Research Area DNA/RNA, Apoptosis/Necrosis
Pathways Cell Division Cycle
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-GADD45G antibody (Growth Arrest and DNA-Damage-Inducible, gamma) (N-Term) (ABIN952425) Western blot analysis of GADD45G Antibody (N-term) in A549 cell line lysates (35ug/la...
Background publications Flores, Burnstein: "GADD45gamma: a new vitamin D-regulated gene that is antiproliferative in prostate cancer cells." in: Endocrinology, Vol. 151, Issue 10, pp. 4654-64, 2010 (PubMed).

Zhang, Li, Shao et al.: "Semi-quantitative detection of GADD45-gamma methylation levels in gastric, colorectal and pancreatic cancers using methylation-sensitive high-resolution melting analysis." in: Journal of cancer research and clinical oncology, Vol. 136, Issue 8, pp. 1267-73, 2010 (PubMed).

Yu, Cho, Park et al.: "Urinary GADD45gamma expression is associated with progression of lgA nephropathy." in: American journal of nephrology, Vol. 30, Issue 2, pp. 135-9, 2009 (PubMed).

Palmieri, Wilson, Iversen et al.: "Polymorphism in the IL18 gene and epithelial ovarian cancer in non-Hispanic white women. ..." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 17, Issue 12, pp. 3567-72, 2008 (PubMed).

Zhu, Shao, Xu et al.: "Gadd45-alpha and Gadd45-gamma utilize p38 and JNK signaling pathways to induce cell cycle G2/M arrest in Hep-G2 hepatoma cells." in: Molecular biology reports, Vol. 36, Issue 8, pp. 2075-85, 2009 (PubMed).