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IL12RB2 antibody (C-Term)
IL12RB2
Reactivity: Human
WB, FACS, IHC (p), EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-IL12RB2 Antibody
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Target
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IL12RB2
(Interleukin 12 Receptor, beta 2 (IL12RB2))
Binding Specificity
All epitopes for IL12RB2 antibodies
AA 759-788, C-Term
Reactivity
All reactivities for IL12RB2 antibodies
Human
Host
All hosts for IL12RB2 antibodies
Rabbit
Clonality
All clonalities for IL12RB2 antibodies
Polyclonal
Conjugate
All conjugates for IL12RB2 antibodies
This IL12RB2 antibody is un-conjugated
Application
All applications for IL12RB2 antibodies
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Specificity
This antibody detects human IL12RB2 at C-term.
Cross-Reactivity (Details)
Species reactivity (tested):Human
Purification
Purified through a protein A column; followed by peptide affinity purification.
Immunogen
Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 759-788aa) of human IL12RB2.
Isotype
Ig Fraction
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Discover our top product IL12RB2 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) Sodium Azide.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for IL12RB2
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Target
IL12RB2
(Interleukin 12 Receptor, beta 2 (IL12RB2))
Alternative Name
IL12RB2 (IL12RB2 Products )
Synonyms
IL12RB2 antibody, A930027I18Rik antibody, IL-12RB2 antibody, Ifnm antibody, interleukin 12 receptor subunit beta 2 antibody, interleukin 12 receptor, beta 2 antibody, IL12RB2 antibody, Il12rb2 antibody
Background
The protein encoded by the IL12RB2 gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense.Synonyms: IL-12 receptor beta-2, IL-12R-beta-2, Interleukin-12 receptor beta-2 chain
Gene ID
3595
NCBI Accession
NP_001550
Pathways
JAK-STAT Signaling
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