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Sca-1/Ly-6A/E antibody (PE)

Ly6a Reactivity: Mouse FACS Host: Rat Monoclonal CT-6A-6E PE
Catalog No. ABIN953252
  • Target See all Sca-1/Ly-6A/E (Ly6a) Antibodies
    Sca-1/Ly-6A/E (Ly6a) (Lymphocyte Antigen 6 Complex, Locus A (Ly6a))
    Reactivity
    • 61
    • 6
    • 1
    Mouse
    Host
    • 40
    • 26
    Rat
    Clonality
    • 45
    • 17
    Monoclonal
    Conjugate
    • 16
    • 6
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Sca-1/Ly-6A/E antibody is conjugated to PE
    Application
    • 40
    • 20
    • 16
    • 8
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificity
    This monoclonal antibody recognizes Sca-1 (Ly-6A.2/6E.1), a cell surface antigen used in the identification of hematopoietic stem cells.
    Purification
    Affinity chromatography on Protein G
    Clone
    CT-6A-6E
    Isotype
    IgG2b
    Top Product
    Discover our top product Ly6a Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0,1 mg/mL
    Buffer
    PBS containing 0.02 % sodium azide (NaN3) as preservative A highly purified grade of BSA has been added as a stablizing protein to bring the final protein concentration to 4-5 mg/mL after conjugation.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    DO NOT FREEZE!
    Storage
    4 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C.
  • Target
    Sca-1/Ly-6A/E (Ly6a) (Lymphocyte Antigen 6 Complex, Locus A (Ly6a))
    Alternative Name
    Ly6A/E / SCA1 (Ly6a Products)
    Synonyms
    Ly-6A.2 antibody, Ly-6A/E antibody, Ly-6E.1 antibody, Sca-1 antibody, Sca1 antibody, TAP antibody, lymphocyte antigen 6 complex, locus A antibody, Ly6a antibody
    Background
    Ly6A/E is a member of the Ly-6 antigen family. The Thy-1lo, Lin- (lineage-negative, not expressing B220, Gr-1, Mac-1, CD4 or CD8), Sca-1+ population of bone marrow cells are highly purified, perhaps homogenous, pluripotent stem cells. This antigen is also present on various other tissues. Specific staining of the parenchymal cells can be demonstrated in thymus, spleen and kidney where as only vasculature reacts with anti-Sca-1 in brain, heart and liver (and possibly in lung). Also, Sca-1 is a T cell activation antigen, as surface expression of the antigen increases upon Con A activation of T lymphocytes. Sca-1 appears to have a molecular mass of 8 kDa under non-reducing conditions and 18 kDa under reducing conditions, indicating the presence of intra-chain disulfide bonds.Synonyms: Ly-6A.2/Ly-6E.1, Lymphocyte antigen 6A-2/6E-1, SCA-1, Stem cell antigen 1, T-cell-activating protein, TAP
    Gene ID
    110454
    NCBI Accession
    NP_034868
    UniProt
    P05533
    Pathways
    Sensory Perception of Sound, Activated T Cell Proliferation
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