You are viewing an incomplete version of our website. Please click to reload the website as full version.

PITRM1 antibody (Pitrilysin Metallopeptidase 1) (AA 497-526)

Details for Product anti-PITRM1 Antibody No. ABIN954153, Supplier: Login to see New
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Synonyms PITRM1, 2310012C15Rik, AA410010, MP-1, MP1, Ntup1, PreP, mKIAA1104, wu:fa03d09, zgc:55469
AA 497-526, Middle Region
(15), (11), (7), (5), (5), (2), (2), (2), (2), (2), (1), (1), (1)
(40), (11), (6), (1), (1), (1), (1), (1), (1), (1), (1)
(42), (3)
This PITRM1 antibody is un-conjugated
(4), (4), (2), (2), (2), (2)
Enzyme Immunoassay (EIA), Western Blotting (WB)
(38), (28), (4), (4), (3), (2), (2)
Pubmed 5 references available
Supplier Login to see New
Catalog number from supplier Login to see New
Quantity 0.4 mL
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen KLH conjugated synthetic peptide between 497-526 amino acids from the Central region of human PITRM1
Isotype Ig
Purification Protein A column, followed by peptide affinity purification
Alternative Name PITRM1 (PITRM1 Antibody Abstract)
Background ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference.Synonyms: KIAA1104, MP1, Metalloprotease 1, Pitrilysin metalloproteinase 1, Presequence protease mitochondrial
Molecular Weight 117455 Da
Gene ID 9606
Research Area Proteolysis / Ubiquitin
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-PITRM1 antibody (Pitrilysin Metallopeptidase 1) (AA 497-526) (ABIN954153) Western blot analysis of PITRM1 Antibody (Center) in MDA-MB231 cell line lysates (35u...
Background publications Yoshida, Kato, Yokoi et al.: "Association of genetic variants with hemorrhagic stroke in Japanese individuals." in: International journal of molecular medicine, Vol. 25, Issue 4, pp. 649-56, 2010 (PubMed).

Pinho, Björk, Alikhani et al.: "Genetic and biochemical studies of SNPs of the mitochondrial A beta-degrading protease, hPreP." in: Neuroscience letters, Vol. 469, Issue 2, pp. 204-8, 2010 (PubMed).

Oguri, Kato, Yokoi et al.: "Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals." in: American journal of hypertension, Vol. 23, Issue 1, pp. 70-7, 2009 (PubMed).

Yoshida, Kato, Yokoi et al.: "Association of gene polymorphisms with chronic kidney disease in Japanese individuals." in: International journal of molecular medicine, Vol. 24, Issue 4, pp. 539-47, 2009 (PubMed).

Chow, Gakh, Payne et al.: "Mammalian pitrilysin: substrate specificity and mitochondrial targeting." in: Biochemistry, Vol. 48, Issue 13, pp. 2868-77, 2009 (PubMed).

Catalog No. ABIN954153
Plus shipping costs $45.00

Order hotline:

  • +1 877 302 8632
  • +1 888 205 9894 (TF)