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Signaling threshold Regulating Transmembrane Adaptor 1 (SIT1) (C-Term), (AA 160-189) antibody

Details for Product No. ABIN954810
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Antigen
Synonyms RP11-331F9.5, SIT, SIT-R, Sit, SIT1
Epitope
C-Term, AA 160-189
(7), (6), (3), (1), (1)
Reactivity
Human
(34), (13), (12)
Host
Rabbit
(21), (13), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(4), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(21), (13), (10), (10), (9), (4), (1), (1), (1), (1)
Pubmed 4 references available
Quantity 0.4 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Catalog No. ABIN954810
357.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen KLH conjugated synthetic peptide between 160-189 amino acids from the C-terminal region of Human SIT1 Genename: SIT1
Specificity This antibody recognizes Human SIT1 / SIT (C-term).
Purification Affinity Chromatography on Protein A
Alternative Name SIT1 / SIT
Background Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells. Involved in positive selection of T-cells.
Alternate names: SHP2-interacting transmembrane adapter protein, Signaling threshold-regulating transmembrane adapter 1, Suppression-inducing transmembrane adapter 1
Molecular Weight 21126 Da
Gene ID 27240
NCBI Accession NP_055265
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS 0.09% Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Rush, Moritz, Lee et al.: "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells." in: Nature biotechnology, Vol. 23, Issue 1, pp. 94-101, 2005 (PubMed).

Tao, Wollscheid, OBrien et al.: "Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry." in: Nature methods, Vol. 2, Issue 8, pp. 591-8, 2005 (PubMed).

Tedoldi, Paterson, Hansmann et al.: "Transmembrane adaptor molecules: a new category of lymphoid-cell markers." in: Blood, Vol. 107, Issue 1, pp. 213-21, 2005 (PubMed).

Chapuis, Hot, Hansmannel et al.: "Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer's disease...." in: Molecular psychiatry, Vol. 14, Issue 11, pp. 1004-16, 2009 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN954810
357.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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