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Details for Product No. ABIN954810

Signaling threshold Regulating Transmembrane Adaptor 1 (SIT1) (C-Term), (AA 160-189) antibody

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Antigen
Synonyms RP11-331F9.5, SIT, SIT-R, Sit, SIT1
Epitope
»Alternatives C-Term, AA 160-189
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives ELISA, Western Blotting (WB)
Pubmed 4 references available
Catalog no. ABIN954810
Quantity 0.4 mL
Price
346.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days
Immunogen KLH conjugated synthetic peptide between 160-189 amino acids from the C-terminal region of Human SIT1 Genename: SIT1
Specificity This antibody recognizes Human SIT1 / SIT (C-term).
Purification Affinity Chromatography on Protein A
Alternative Name SIT1 / SIT
Background Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells. Involved in positive selection of T-cells.
Alternate names: SHP2-interacting transmembrane adapter protein, Signaling threshold-regulating transmembrane adapter 1, Suppression-inducing transmembrane adapter 1
Molecular Weight 21126 Da
Gene ID 27240
NCBI Accession NP_055265
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS 0.09% Sodium Azide
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Rush, Moritz, Lee et al.: "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells." in: Nature biotechnology, Vol. 23, Issue 1, pp. 94-101, 2005 (PubMed).

Tao, Wollscheid, OBrien et al.: "Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry." in: Nature methods, Vol. 2, Issue 8, pp. 591-8, 2005 (PubMed).

Tedoldi, Paterson, Hansmann et al.: "Transmembrane adaptor molecules: a new category of lymphoid-cell markers." in: Blood, Vol. 107, Issue 1, pp. 213-21, 2005 (PubMed).

Chapuis, Hot, Hansmannel et al.: "Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer's disease." in: Molecular psychiatry, Vol. 14, Issue 11, pp. 1004-16, 2009 (PubMed).

Alternatives for antigen "Signaling threshold Regulating Transmembrane Adaptor 1 (SIT1)", type "Antibodies"
Hosts (17), (16), (2)
Reactivities (34), (12), (12)
Applications (20), (13), (12), (10), (6), (3), (1), (1)
Conjugates (4), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (3), (3), (2), (1), (1)
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