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SIT1 Products

(Signaling threshold Regulating Transmembrane Adaptor 1 (SIT1))

Categories

Negatively regulates T-cell antigen receptor (TCR)- mediated signaling. Involved in positive selection of T-cells.

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Featured SIT1 Categories

SIT1 Antibodies

High quality antibodies with extensive validation data.

SIT1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SIT1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application FACS, IP, WB
Validations
  • (2)
  • (2)
Cat. No. ABIN125717
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application FACS, IP, WB
Validations
  • (2)
  • (1)
Cat. No. ABIN94465
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Rat
Application ICC, IHC, WB
Validations
  • (1)
Cat. No. ABIN1860565
Quantity 100 μL
Datasheet Datasheet

Recommended SIT1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3077166
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3125690
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3097910
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our SIT1 products

Tedoldi, Paterson, Hansmann, Natkunam, Rüdiger, Angelisova, Du, Roberton, Roncador, Sanchez, Pozzobon, Masir, Barry, Pileri, Mason, Marafioti, Horejsí: "Transmembrane adaptor molecules: a new category of lymphoid-cell markers." in: Blood, Vol. 107, Issue 1, pp. 213-21, (2005) (PubMed).

Horejsí, Zhang, Schraven: "Transmembrane adaptor proteins: organizers of immunoreceptor signalling." in: Nature reviews. Immunology, Vol. 4, Issue 8, pp. 603-16, (2004) (PubMed).

Hübener, Mincheva, Lichter, Schraven, Bruyns: "Complete sequence, genomic organization, and chromosomal localization of the human gene encoding the SHP2-interacting transmembrane adaptor protein (SIT)." in: Immunogenetics, Vol. 53, Issue 4, pp. 337-41, (2001) (PubMed).

Marie-Cardine, Kirchgessner, Bruyns, Shevchenko, Mann, Autschbach, Ratnofsky, Meuer, Schraven: "SHP2-interacting transmembrane adaptor protein (SIT), a novel disulfide-linked dimer regulating human T cell activation." in: The Journal of experimental medicine, Vol. 189, Issue 8, pp. 1181-94, (1999) (PubMed).

Synonyms and alternative names related to SIT1

signaling threshold regulating transmembrane adaptor 1 (SIT1), signaling threshold regulating transmembrane adaptor 1 (Sit1), suppression inducing transmembrane adaptor 1 (Sit1), RP11-331F9.5, SIT, Sit, SIT-R, SIT1

Protein level used designations for SIT1

  • signaling threshold-regulating transmembrane adapter 1
  • signaling threshold regulating transmembrane adaptor 1
  • SHP-2 interacting transmembrane adaptor protein
  • SHP2 interacting transmembrane adaptor
  • SHP2-interacting transmembrane adapter protein
  • SHP2-interacting transmembrane adaptor protein
  • gp30/40
  • suppression inducing transmembrane adaptor 1
  • suppression-inducing transmembrane adapter 1
  • SHP2 interacting transmembrane adaptor protein
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