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Apolipoprotein B MRNA Editing Enzyme, Catalytic Polypeptide-Like 3G (APOBEC3G) (N-Term) antibody

Details for Product No. ABIN965574
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Antigen
Synonyms A3G, ARCD, ARP-9, ARP9, CEM-15, CEM15, bK150C2.7, dJ494G10.1
Epitope
N-Term
(25), (19), (9), (7), (7), (7), (2), (2), (1), (1)
Reactivity
Human
(86), (2), (1)
Host
Rabbit
(66), (16), (7)
Clonality
Polyclonal
Conjugate
Un-conjugated
(5), (5), (5), (5), (5), (5)
Application
Immunohistochemistry (IHC)
(85), (58), (33), (20), (2), (1)
Pubmed 5 references available
Quantity 0.1 mg
Options
Shipping to United States (Change)
Availability Will be delivered in 5 to 7 Business Days
Catalog No. ABIN965574
452.38 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human APOBEC3G (apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3G)
Alternative Name APOBEC3G
Background APOBEC3G (apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3G) is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. APOBEC3G is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. APOBEC3G has been found to be a specific inhibitor of human immunodeficiency virus-1 (HIV-1) infectivity.
Research Area Immunology, Chromatin Binding Proteins
Restrictions For Research Use only
Product cited in: Kamada, Igarashi, Martin et al.: "Generation of HIV-1 derivatives that productively infect macaque monkey lymphoid cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 45, pp. 16959-64, 2006 (PubMed).

Vetter, DAquila: "Cytoplasmic APOBEC3G restricts incoming Vif-positive human immunodeficiency virus type 1 and increases two-long terminal repeat circle formation in activated T-helper-subtype cells." in: Journal of virology, Vol. 83, Issue 17, pp. 8646-54, 2009 (PubMed).

Dang, Wang, Zhou et al.: "Identification of a novel WxSLVK motif in the N terminus of human immunodeficiency virus and simian immunodeficiency virus Vif that is critical for APOBEC3G and APOBEC3F neutralization." in: Journal of virology, Vol. 83, Issue 17, pp. 8544-52, 2009 (PubMed).

Chen, He, Wang et al.: "A patch of positively charged amino acids surrounding the human immunodeficiency virus type 1 Vif SLVx4Yx9Y motif influences its interaction with APOBEC3G." in: Journal of virology, Vol. 83, Issue 17, pp. 8674-82, 2009 (PubMed).

Pido-Lopez, Jeffrey, Wang et al.: "The effect of allogeneic in vitro stimulation and in vivo immunization on memory CD4(+) T-cell APOBEC3G expression and HIV-1 infectivity." in: European journal of immunology, Vol. 39, Issue 7, pp. 1956-65, 2009 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN965574
452.38 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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