APOBEC3G antibody (AA 1-384)

Catalog No. ABIN7150160

Product Details anti-APOBEC3G Antibody

Target: APOBEC3G (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3G (APOBEC3G))

Binding Specificity: AA 1-384

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APOBEC3G antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human DNA dC->dU-editing enzyme APOBEC-3G protein (1-384AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for APOBEC3G

Target: APOBEC3G (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3G (APOBEC3G))

Alternative Name: APOBEC3G (APOBEC3G Products)

Synonyms: A3G antibody, ARCD antibody, ARP-9 antibody, ARP9 antibody, CEM-15 antibody, CEM15 antibody, bK150C2.7 antibody, dJ494G10.1 antibody, apolipoprotein B mRNA editing enzyme catalytic subunit 3G antibody, APOBEC3G antibody

Background:

Background: DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. Exhibits potent antiviral activity against vif-deficient HIV-1. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double-stranded RNA. Exhibits antiviral activity also against simian immunodeficiency viruses (SIVs), hepatitis B virus (HBV), equine infectious anemia virus (EIAV), xenotropic MuLV-related virus (XMRV) and simian foamy virus (SFV). May inhibit the mobility of LTR and non-LTR retrotransposons.

Aliases: A3G antibody, ABC3G_HUMAN antibody, APOBEC related cytidine deaminase antibody, APOBEC related protein antibody, APOBEC-related cytidine deaminase antibody, APOBEC-related protein 9 antibody, APOBEC-related protein antibody, APOBEC3G antibody, Apolipoprotein B editing enzyme catalytic polypeptide like 3G antibody, Apolipoprotein B mRNA editing enzyme catalytic polypeptide 3G antibody, Apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3G antibody, Apolipoprotein B mRNA editing enzyme catalytic subunit 3G antibody, apolipoprotein B mRNA editing enzyme cytidine deaminase antibody, apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like antibody, ARCD antibody, ARP-9 antibody, ARP9 antibody, bK150C2.7 antibody, CEM-15 antibody, CEM15 antibody, deoxycytidine deaminase antibody, dJ494G10.1 antibody, DNA dC dU editing enzyme APOBEC 3G antibody, DNA dC->dU editing enzyme antibody, DNA dC->dU-editing enzyme APOBEC-3G antibody, EC 3.5.4. antibody, FLJ12740 antibody, MDS019 antibody, OTTHUMP00000028911 antibody, phorbolin-like protein antibody, phorbolin-like protein MDS019 antibody

UniProt: Q9HC16