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Details for Product No. ABIN965878

Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR) (AA 1339-1351) antibody

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Antigen
Synonyms CF, MRP7, ABC35, ABCC7, CFTR/MRP, TNR-CFTR, dJ760C5.1, AW495489, Abcc7, RGD1561193, CFTR
Epitope
»Alternatives AA 1339-1351
Reactivity
»Alternatives Human, Sheep (Ovine)
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (IHC)
Pubmed 5 references available
Catalog no. ABIN965878
Quantity 0.1 mg
Price
357.50 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 5 to 7 Business Days
Immunogen Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to residues 1339-1351 of human CFTR (Cystic fibrosis transmembrane conductance regulator)
Alternative Name CFTR
Background CFTR (Cystic fibrosis transmembrane conductance regulator) is involved in the transport of chloride ions and binds SLC9A3R1. CFTR is an integral membrane protein. Defects in CFTR are the cause of cystic fibrosis (CF) , also known as mucoviscidosis. It belongs to the ABC transporter family and MRP subfamily.
Restrictions For Research Use only
Product cited in: Picciotto, Cohn, Bertuzzi et al.: "Phosphorylation of the cystic fibrosis transmembrane conductance regulator." in: The Journal of biological chemistry, Vol. 267, Issue 18, pp. 12742-52, 1992 (PubMed).

Cutting, Kasch, Rosenstein et al.: "A cluster of cystic fibrosis mutations in the first nucleotide-binding fold of the cystic fibrosis conductance regulator protein." in: Nature, Vol. 346, Issue 6282, pp. 366-9, 1990 (PubMed).

Zielenski, Rozmahel, Bozon et al.: "Genomic DNA sequence of the cystic fibrosis transmembrane conductance regulator (CFTR) gene." in: Genomics, Vol. 10, Issue 1, pp. 214-28, 1991 (PubMed).

Riordan, Rommens, Kerem et al.: "Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA." in: Science (New York, N.Y.), Vol. 245, Issue 4922, pp. 1066-73, 1989 (PubMed).

Karthikeyan, Leung, Ladias: "Structural basis of the Na+/H+ exchanger regulatory factor PDZ1 interaction with the carboxyl-terminal region of the cystic fibrosis transmembrane conductance regulator." in: The Journal of biological chemistry, Vol. 276, Issue 23, pp. 19683-6, 2001 (PubMed).

Alternatives for antigen "Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR)", type "Antibodies"
Hosts (45), (33), (3), (1)
Reactivities (79), (31), (29), (14), (14), (12), (12), (1), (1)
Applications (54), (31), (28), (27), (26), (13), (12), (10), (2), (2), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (14), (5), (5), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
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