Purified by antigen-specific affinity chromatography.
Immunogen
Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human DAT(Sodium-dependent dopamine transporter)
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Pristupa, Wilson, Hoffman, Kish, Niznik: "Pharmacological heterogeneity of the cloned and native human dopamine transporter: disassociation of [3H]WIN 35,428 and [3H]GBR 12,935 binding." in: Molecular pharmacology, Vol. 45, Issue 1, pp. 125-35, (1994) (PubMed).
Vandenbergh, Persico, Uhl: "A human dopamine transporter cDNA predicts reduced glycosylation, displays a novel repetitive element and provides racially-dimorphic TaqI RFLPs." in: Brain research. Molecular brain research, Vol. 15, Issue 1-2, pp. 161-6, (1992) (PubMed).
Target
SLC6A3
(Solute Carrier Family 6 (Neurotransmitter Transporter, Dopamine), Member 3 (SLC6A3))
DAT antibody, SLC6A3 antibody, Dat1 antibody, DAT1 antibody, PKDYS antibody, solute carrier family 6 member 3 antibody, solute carrier family 6 (neurotransmitter transporter), member 3 antibody, Sodium-dependent dopamine transporter antibody, solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 antibody, SLC6A3 antibody, slc6a3 antibody, dat-1 antibody, Slc6a3 antibody
Background
DAT(Sodium-dependent dopamine transporter)is an amine transporter. DAT terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals. This protein is the target of psychomotor stimulants such as amphetamines or cocaine. It belongs to the sodium: neurotransmitter symporter (SNF) family.