Solute Carrier Family 6 (Neurotransmitter Transporter, Dopamine), Member 3 (SLC6A3) (N-Term) antibody

Details for Product No. ABIN965973
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Antigen
Synonyms DAT, Dat1, DAT1, PKDYS, SLC6A3
Epitope
N-Term
(20), (8), (4), (2), (1), (1), (1), (1)
Reactivity
Human
(51), (23), (22), (12), (12), (4)
Host
Rabbit
(52), (5), (3), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC)
(51), (25), (14), (11), (10), (9), (2), (1), (1), (1)
Pubmed 6 references available
Catalog no. ABIN965973
Quantity 0.1 mg
Price
288.75 $   Plus shipping costs $45.00
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Immunogen Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human DAT(Sodium-dependent dopamine transporter)
Purification Purified by antigen-specific affinity chromatography.
Alternative Name DAT
Background DAT(Sodium-dependent dopamine transporter)is an amine transporter. DAT terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals. This protein is the target of psychomotor stimulants such as amphetamines or cocaine. It belongs to the sodium: neurotransmitter symporter (SNF) family.
Application Notes ELISA, Western blotting: 1µg/ml for 2hrs.
Restrictions For Research Use only
Format Liquid
Buffer This antibody is stored in PBS, 50% glycerol
Preservative Sodium azide
Storage -20 °C
Product cited in: Vandenbergh, Persico, Uhl: "A human dopamine transporter cDNA predicts reduced glycosylation, displays a novel repetitive element and provides racially-dimorphic TaqI RFLPs." in: Brain research. Molecular brain research, Vol. 15, Issue 1-2, pp. 161-6, 1992 (PubMed).

Donovan, Vandenbergh, Perry et al.: "Human and mouse dopamine transporter genes: conservation of 5'-flanking sequence elements and gene structures." in: Brain research. Molecular brain research, Vol. 30, Issue 2, pp. 327-35, 1995 (PubMed).

Pristupa, Wilson, Hoffman et al.: "Pharmacological heterogeneity of the cloned and native human dopamine transporter: disassociation of [3H]WIN 35,428 and [3H]GBR 12,935 binding." in: Molecular pharmacology, Vol. 45, Issue 1, pp. 125-35, 1994 (PubMed).

Vandenbergh, Thompson, Cook et al.: "Human dopamine transporter gene: coding region conservation among normal, Tourette's disorder, alcohol dependence and attention-deficit hyperactivity disorder populations." in: Molecular psychiatry, Vol. 5, Issue 3, pp. 283-92, 2000 (PubMed).

Greenwood, Alexander, Keck et al.: "Evidence for linkage disequilibrium between the dopamine transporter and bipolar disorder." in: American journal of medical genetics, Vol. 105, Issue 2, pp. 145-51, 2001 (PubMed).

Torres, Yao, Mohn et al.: "Functional interaction between monoamine plasma membrane transporters and the synaptic PDZ domain-containing protein PICK1." in: Neuron, Vol. 30, Issue 1, pp. 121-34, 2001 (PubMed).

Hosts (52), (5), (3), (1)
Reactivities (51), (23), (22), (12), (12), (4)
Applications (51), (25), (14), (11), (10), (9), (2), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (20), (8), (4), (2), (1), (1), (1), (1)
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