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Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) antibody

Antigen

Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA)
Synonyms IKBA, MAD-3, NFKBI
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human, Mouse (Murine), Rat (Rattus)
Conjugate
Alternatives Un-conjugated
Application
Alternatives Immunohistochemistry (IHC)
5 references available
Catalog no. ABIN966365
Quantity 100ug  (100ug/100ul)  (Variants)
Price 385.00 $   Plus shipping costs $45.00
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Additional Information
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Alternative name IkB-alpha
Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human IB- around the phosphorylation site of serine 32/36 (H-D-SP-G-L- D-SP -M-K).
Specificity IB- (Ab-32/36) antibody detects endogenous levels of total IB- protein.

Application Details
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Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Concentration 100ug/100ul
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative 0.02% Sodium Azide
Storage Store at -20°C/1 year.
Restrictions For Research Use only

Publications
Application Details Alternatives Variants back to top

Product Schubert, Neeman, Resnick: "A novel mechanism for the inhibition of NF-kappaB activation in vascular endothelial cells by natural antioxidants." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 16, Issue 14, pp. 1931-3, 2002 (PubMed).

Fan, Yang, Engelhardt: "Temporal pattern of NFkappaB activation influences apoptotic cell fate in a stimuli-dependent fashion." in: Journal of cell science, Vol. 115, Issue Pt 24, pp. 4843-53, 2002 (PubMed).

Nair, Venkatraman, Maliekal et al.: "NF-kappaB is constitutively activated in high-grade squamous intraepithelial lesions and squamous cell carcinomas of the human uterine cervix." in: Oncogene, Vol. 22, Issue 1, pp. 50-8, 2003 (PubMed).

Courtois, Smahi, Reichenbach et al.: "A hypermorphic IkappaBalpha mutation is associated with autosomal dominant anhidrotic ectodermal dysplasia and T cell immunodeficiency." in: The Journal of clinical investigation, Vol. 112, Issue 7, pp. 1108-15, 2003 (PubMed).

Mattioli, Sebald, Bucher et al.: "Transient and selective NF-kappa B p65 serine 536 phosphorylation induced by T cell costimulation is mediated by I kappa B kinase beta and controls the kinetics of p65 nuclear import." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 172, Issue 10, pp. 6336-44, 2004 (PubMed).

Alternatives
Application Details Publications Variants back to top

Alternatives for antigen "Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA)", type "Antibodies"
Hosts Rabbit (145), Mouse (26), Sheep (4), Goat (1)
Reactivities Human (166), Mouse (Murine) (74), Rat (Rattus) (65), Cow (Bovine) (20), Pig (Porcine) (19), Sheep (Ovine) (15), Dog (Canine) (8), Chicken (7), Cat (Feline) (1), Hamster (1), Rabbit (1)
Applications Western Blotting (WB) (115), ELISA (66), Immunohistochemistry (IHC) (57), Immunofluorescence (IF) (50), Immunoprecipitation (IP) (36), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (29), Flow Cytometry (FACS) (3), Gel Shift (GS) (3), Immunocytochemistry (ICC) (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Dot Blot (Dot) (2), Electrophoretic Mobility-Shift Assay (EMSA) (1), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Fixed) (IHC (fx)) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
Conjugates Biotin (8), Alexa Fluor 350 (4), Alexa Fluor 488 (4), Alexa Fluor 555 (4), Alexa Fluor 647 (4), PE,Cy5.5 (4), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1)
Epitopes pTyr42 (15), pSer32, pSer36 (13), C-Term (8), AA 32-36 (6), N-Term (5), pTyr305 (5), AA 32-291 (4), pSer36,pSer32 (4), Ser32, Ser36 (3), AA 34-48 (2), Pser32,pSer36 (2), Ser32 (2), Ser32,Ser36 (2), Tyr181 (2), Tyr42 (2), AA 130-143 (1), AA 32-47 (1), Internal Region (1), Ser23 (1), Sumoylation Site (1), pSer32 (1), pSer32,pSer36 (1), pSer320 (1), pSer36 (1), pSer893 (1)