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Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) antibody

Details for Product No. ABIN966366
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Antigen
Synonyms AI462015, Nfkbi, IKBA, MAD-3, NFKBI, ECI-6/IKBA, RL/IF-1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(287), (165), (144), (41), (38), (14), (13), (2)
Host
Rabbit
(262), (31), (6)
Clonality
Polyclonal
Conjugate
Un-conjugated
(9), (7), (7), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3)
Application
Immunohistochemistry (IHC)
(221), (110), (95), (47), (42), (40), (37), (13), (9), (8), (5), (4), (2), (1)
Pubmed 5 references available
Quantity 100 µg
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Catalog No. ABIN966366
385.00 $
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Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human IB- around the phosphorylation site of tyrosine 42 (E-E-YP-E-Q).
Specificity IB- (Ab-42) antibody detects endogenous levels of total IB- protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name IkB-alpha
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Franzoso, Carlson, Xing et al.: "Requirement for NF-kappaB in osteoclast and B-cell development." in: Genes & development, Vol. 11, Issue 24, pp. 3482-96, 1998 (PubMed).

Liu, Kwak, Bex et al.: "DNA-dependent protein kinase phosphorylation of IkappaB alpha and IkappaB beta regulates NF-kappaB DNA binding properties." in: Molecular and cellular biology, Vol. 18, Issue 7, pp. 4221-34, 1998 (PubMed).

Shrivastava, Manna, Ray et al.: "Ectopic expression of hepatitis C virus core protein differentially regulates nuclear transcription factors." in: Journal of virology, Vol. 72, Issue 12, pp. 9722-8, 1998 (PubMed).

Béraud, Henzel, Baeuerle: "Involvement of regulatory and catalytic subunits of phosphoinositide 3-kinase in NF-kappaB activation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 2, pp. 429-34, 1999 (PubMed).

Sundström, Ota, Dimberg et al.: "Hepatitis C virus core protein induces an anergic state characterized by decreased interleukin-2 production and perturbation of mitogen-activated protein kinase responses." in: Journal of virology, Vol. 79, Issue 4, pp. 2230-9, 2005 (PubMed).

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