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NFKBIA antibody (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha)

Details for Product anti-NFKBIA Antibody No. ABIN966366, Supplier: Login to see
Antigen
  • AI462015
  • Nfkbi
  • IKBA
  • MAD-3
  • NFKBI
  • ECI-6/IKBA
  • RL/IF-1
Alternatives
anti-Human NFKBIA antibody for Western Blotting
Reactivity
Human, Mouse (Murine), Rat (Rattus)
387
173
136
17
12
8
6
4
2
1
Host
Rabbit
336
57
6
1
Clonality
Polyclonal
Conjugate
This NFKBIA antibody is un-conjugated
14
11
9
8
6
6
4
3
3
3
3
3
3
3
3
1
Application
Immunohistochemistry (IHC)
277
141
124
64
57
53
34
19
16
15
6
5
4
3
3
1
1
1
1
1
Supplier
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Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human IB- around the phosphorylation site of tyrosine 42 (E-E-YP-E-Q).
Specificity IB- (Ab-42) antibody detects endogenous levels of total IB- protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name IkB-alpha (NFKBIA Antibody Abstract)
Pathways NF-kappaB Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Sundstrm, Ota, Dimberg et al.: "Hepatitis C virus core protein induces an anergic state characterized by decreased interleukin-2 production and perturbation of mitogen-activated protein kinase responses." in: Journal of virology, Vol. 79, Issue 4, pp. 2230-9, 2005 (PubMed).

Béraud, Henzel, Baeuerle: "Involvement of regulatory and catalytic subunits of phosphoinositide 3-kinase in NF-kappaB activation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 2, pp. 429-34, 1999 (PubMed).

Shrivastava, Manna, Ray et al.: "Ectopic expression of hepatitis C virus core protein differentially regulates nuclear transcription factors." in: Journal of virology, Vol. 72, Issue 12, pp. 9722-8, 1998 (PubMed).

Liu, Kwak, Bex et al.: "DNA-dependent protein kinase phosphorylation of IkappaB alpha and IkappaB beta regulates NF-kappaB DNA binding properties." in: Molecular and cellular biology, Vol. 18, Issue 7, pp. 4221-34, 1998 (PubMed).

Franzoso, Carlson, Xing et al.: "Requirement for NF-kappaB in osteoclast and B-cell development." in: Genes & development, Vol. 11, Issue 24, pp. 3482-96, 1998 (PubMed).

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