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FYN Oncogene Related To SRC, FGR, YES (FYN) antibody

Antigen

FYN Oncogene Related To SRC, FGR, YES (FYN)
Synonyms FYN, fyn, MGC52878, MGC132140, zgc:109996, c-fyn, zgc:86720, SLK, SYN, MGC45350, AI448320, AW552119, MGC115870, PKC
Clonality Monoclonal (2H8)
Host
Alternatives

Mouse
Reactivity
Alternatives

Human, Mouse (Murine)
Conjugate
Alternatives Un-conjugated
Application
Alternatives ELISA, Western Blotting (WB)
3 references available
Catalog no. ABIN969160
Quantity 0.1ml  (Variants)
Price 396.00 $   Plus shipping costs $45.00
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Additional Information
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Alternative name FYN
Gene ID 2534
Immunogen Purified recombinant fragment of human FYN expressed in E. Coli.
Format Liquid
Isotype IgG1
Clone 2H8
Description This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist.
Synonyms: SLK, SYN, MGC45350
Molecular Weight 61kDa

Application Details
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Application Notes Western Blotting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Purification Ascites
Buffer Ascitic fluid containing 0.03% sodium azide.
Preservative 0.03% sodium azide
Storage Store at 4℃, for long term storage, store at -20℃.
Restrictions For Research Use only

Publications
Application Details Alternatives Variants back to top

Product Kitkumthorn, Yanatatsanajit, Kiatpongsan et al.: "Cyclin A1 promoter hypermethylation in human papillomavirus-associated cervical cancer." in: BMC cancer, Vol. 6, pp. 55, 2006 (PubMed).

Lu, Zhu, Cvrljevic et al.: "Fyn and SRC are effectors of oncogenic epidermal growth factor receptor signaling in glioblastoma patients." in: Cancer research, Vol. 69, Issue 17, pp. 6889-98, 2009 (PubMed).

Brignatz, Paronetto, Opi et al.: "Alternative splicing modulates autoinhibition and SH3 accessibility in the Src kinase Fyn." in: Molecular and cellular biology, Vol. 29, Issue 24, pp. 6438-48, 2009 (PubMed).

Alternatives
Application Details Publications Variants back to top

Alternatives for antigen "FYN Oncogene Related To SRC, FGR, YES (FYN)", type "Antibodies"
Hosts Rabbit (48), Mouse (27), Goat (7)
Reactivities Human (65), Mouse (Murine) (44), Rat (Rattus) (28), Cow (Bovine) (26), Chicken (24), Dog (Canine) (24), Pig (Porcine) (24)
Applications Western Blotting (WB) (52), Immunofluorescence (IF) (26), ELISA (25), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (22), Immunoprecipitation (IP) (13), Immunohistochemistry (IHC) (9), Immunohistochemistry (Fixed) (IHC (fx)) (5), Functional Studies (Func) (4), Flow Cytometry (FACS) (3), Immunocytochemistry (ICC) (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
Conjugates Alexa Fluor 350 (2), Alexa Fluor 488 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), PE,Cy5.5 (2), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1)
Epitopes N-Term (10), pTyr530 (9), AA 1-206 (4), AA 7-176 (4), C-Term (2), AA 1-197 (1), AA 1-537 (1), AA 23-216 (1), AA 35-51 (1), Internal Region (1), Middle Region (1), pThr2446 (1)