anti-FYN antibody (FYN Oncogene Related To SRC, FGR, YES)

Details for Product anti-FYN Antibody No. ABIN969160
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Synonyms im:6908851, si:dkey-119m7.5, zgc:109996, c-fyn, cfyn-a, SLK, SYN, p59-FYN, PKC, fyn, zgc:86720, AI448320, AW552119
Human, Mouse (Murine)
(185), (93), (38), (7), (6), (6), (1), (1), (1), (1), (1), (1)
(128), (62), (21)
Clonality (Clone)
Monoclonal ()
This FYN antibody is un-conjugated
(7), (7), (7), (7), (7), (7)
ELISA, Western Blotting (WB)
(188), (110), (46), (28), (22), (13), (12), (11), (9), (6), (4), (2), (2), (2), (2), (1)
Pubmed 3 references available
Quantity 100 μL
Shipping to United States ( )
Availability Will be delivered in 3 to 4 Business Days
Immunogen Purified recombinant fragment of human FYN expressed in E. coli.
Clone 2H8
Isotype IgG1
Purification Ascites
Alternative Name FYN (FYN Antibody Abstract)
Background This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist.
Molecular Weight 61 kDa
Gene ID 2534
HGNC 2534
Pathways JAK-STAT Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Supplier Images
ELISA image for anti-FYN antibody (FYN Oncogene Related To SRC, FGR, YES) (ABIN969160) Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 n...
Western Blotting (WB) image for anti-FYN antibody (FYN Oncogene Related To SRC, FGR, YES) (ABIN969160) Figure 2: Western blot analysis using FYN mouse mAb against NIH/3T3 (1) and Hela (2) ...
Product cited in: Brignatz, Paronetto, Opi et al.: "Alternative splicing modulates autoinhibition and SH3 accessibility in the Src kinase Fyn." in: Molecular and cellular biology, Vol. 29, Issue 24, pp. 6438-48, 2009 (PubMed).

Lu, Zhu, Cvrljevic et al.: "Fyn and SRC are effectors of oncogenic epidermal growth factor receptor signaling in glioblastoma patients." in: Cancer research, Vol. 69, Issue 17, pp. 6889-98, 2009 (PubMed).

Kitkumthorn, Yanatatsanajit, Kiatpongsan et al.: "Cyclin A1 promoter hypermethylation in human papillomavirus-associated cervical cancer." in: BMC cancer, Vol. 6, pp. 55, 2006 (PubMed).

Catalog No. ABIN969160
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