Snail Homolog 2 (Drosophila) (SNAI2) antibody

Details for Product No. ABIN969410
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Synonyms slug, ws2d, xSlu, xslug, Snail2, slugh1, XSnail2, snai2, SLUG, SLUGH1, SNAIL2, WS2D, Slug, xsna, Slugh, cb147, cb355, id:ibd5003, sb:cb355, sb:cb569, wu:fb83e12, wu:fd19g11, zgc:92564
(104), (40), (27), (1), (1), (1), (1), (1)
(61), (43)
Clonality (Clone)
Monoclonal ()
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
ELISA, Western Blotting (WB)
(83), (33), (19), (18), (15), (10), (8), (4), (4), (2), (2), (1), (1)
Pubmed 2 references available
Quantity 100 μL
Shipping to United States (Change)
Availability Will be delivered in 3 to 4 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN969410
393.80 $
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Immunogen Purified recombinant fragment of human SNAI2 expressed in E. coli.
Clone 2H5
Isotype IgG1
Purification Ascites
Alternative Name SNAI2
Background Synonyms:
This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. The tumor suppressor protein p53 induces Slug expression in γ-irradiated cells, Slug protects damaged cells from apoptosis by repressing p53-induced transcription of the proapoptotic Bcl-2 family protein Puma. Mutations in this gene may be associated with sporatic cases of neural tube defects.
Molecular Weight 30 kDa
Gene ID 6591
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Supplier Images
anti-Snail Homolog 2 (Drosophila) (SNAI2) antibody Figure 1: Western blot analysis using SNAI2 mouse mAb against SNAI2 (AA: 1-128) -hIgGFc transfected HEK293 cell lysate.
Product cited in: Saegusa, Hashimura, Kuwata et al.: "Requirement of the Akt/beta-catenin pathway for uterine carcinosarcoma genesis, modulating E-cadherin expression through the transactivation of slug." in: The American journal of pathology, Vol. 174, Issue 6, pp. 2107-15, 2009 (PubMed).

Medici, Hay, Olsen: "Snail and Slug promote epithelial-mesenchymal transition through beta-catenin-T-cell factor-4-dependent expression of transforming growth factor-beta3." in: Molecular biology of the cell, Vol. 19, Issue 11, pp. 4875-87, 2008 (PubMed).

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