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SLUG Antibodies

(Snail Family Zinc Finger 2 (SNAI2))
Transcriptional repressor that modulates both activator- dependent and basal transcription. Involved in the generation and migration of neural crest cells. Plays a role in mediating RAF1- induced transcriptional repression of the TJ protein, occludin (OCLN) and subsequent oncogenic transformation of epithelial cells. Represses BRCA2 expression by binding to its E2-box- containing silencer and recruiting CTBP1 and HDAC1 in breast cells. In epidermal keratinocytes, binds to the E-box in ITGA3 promoter and represses its transcription. Involved in the regulation of ITGB1 and ITGB4 expression and cell adhesion and proliferation in epidermal keratinocytes. Binds to E-box2 domain of BSG and activates its expression during TGFB1-induced epithelial-mesenchymal transition (EMT) in hepatocytes. Represses E-Cadherin/CDH1 transcription via E-box elements. Involved in osteoblast maturation. Binds to RUNX2 and SOC9 promoters and may act as a positive and negative transcription regulator, respectively, in osteoblasts. Binds to CXCL12 promoter via E-box regions in mesenchymal stem cells and osteoblasts. Plays an essential role in TWIST1-induced EMT and its ability to promote invasion and metastasis (By similarity). {ECO:0000250}.
anti-Snail Family Zinc Finger 2 (SNAI2) (AA 100-200) antibody anti-Snail Family Zinc Finger 2 (SNAI2) (AA 100-200) antibody anti-Snail Family Zinc Finger 2 (SNAI2) (AA 100-200) antibody (ABIN5542256)

SNAI2 Reactivity: Human ELISA, FACS, ICC, IHC, WB Host: Mouse Monoclonal 4B6D5 unconjugated

anti-Snail Family Zinc Finger 2 (SNAI2) (AA 98-129) antibody anti-Snail Family Zinc Finger 2 (SNAI2) (AA 98-129) antibody anti-Snail Family Zinc Finger 2 (SNAI2) (AA 98-129) antibody (ABIN3032658)

SNAI2 Reactivity: Human, Mouse IF, IHC, ELISA, WB Host: Rabbit Polyclonal unconjugated

anti-Snail Family Zinc Finger 2 (SNAI2) (AA 97-169) antibody anti-Snail Family Zinc Finger 2 (SNAI2) (AA 97-169) antibody anti-Snail Family Zinc Finger 2 (SNAI2) (AA 97-169) antibody (ABIN520276)

SNAI2 Reactivity: Human IF, ELISA, WB Host: Mouse Monoclonal 3C12 unconjugated

SLUG Antibodies by Reactivity

Find SLUG Antibodies for a variety of species such as anti-Human SLUG, anti-Mouse SLUG, anti-Rat SLUG. The species listed below are among those available. Click on a link to go to the corresponding products.

SLUG Antibodies by Application

Find SLUG Antibodies validated for a specific application such as WB, ELISA, IHC, IF. Some of the available applications are listed below. Click on a link to go to the corresponding products.

SLUG Antibodies by Host

Find SLUG Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

SLUG Antibodies by Binding Specificity

Find SLUG Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

SLUG Antibodies by Clonality

Find available monoclonal or polyclonal SLUG Antibodies. Click on a link to go to the corresponding products.

SLUG Antibodies by Clone

Find SLUG Antibodies with a specific Clone. The Clone listed below are among those available. Click on a link to go to the corresponding products.

SLUG Antibodies by Conjugate

Find SLUG Antibodies with a specific conjugate such as Biotin, Alexa Fluor 488, Alexa Fluor 555. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular SLUG Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application IF, ELISA, WB
Validations
  • (5)
Cat. No. ABIN520274
Quantity 100 μg
Datasheet Datasheet

Application IHC, WB
Validations
  • (4)
Cat. No. ABIN2777851
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IHC, WB
Validations
  • (4)
Cat. No. ABIN6265201
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application FACS, IF, IHC, IHC (p), WB
Validations
  • (4)
Cat. No. ABIN1500979
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (3)
Cat. No. ABIN3032603
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
  • (2)
  • (2)
Cat. No. ABIN520278
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application EIA, IHC (p), WB
Validations
  • (3)
  • (2)
Cat. No. ABIN2853627
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (2)
  • (1)
Cat. No. ABIN969410
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, WB
Validations
  • (1)
  • (1)
Cat. No. ABIN3021318
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IF, WB
Validations
  • (2)
Cat. No. ABIN948475
Quantity 50 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application EIA, IF, WB
Validations
  • (2)
Cat. No. ABIN500780
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human, Mouse
Application EIA, WB
Validations
  • (6)
  • (1)
Cat. No. ABIN357448
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Bat, Chicken, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Pig, Rabbit, Sheep
Application IHC, IHC (p), WB
Validations
  • (2)
Cat. No. ABIN6746994
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC
Validations
  • (5)
Cat. No. ABIN967057
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC
Validations
  • (5)
Cat. No. ABIN967059
Quantity 0.1 mg
Datasheet Datasheet

Latest Publications for our SLUG Antibodies

Yan, Du, Li, Chen, Yan, Chen, Hu, Chang: "CO suppresses prostate cancer cell growth by directly targeting LKB1/AMPK/mTOR pathway in vitro and in vivo." in: Urologic oncology, Vol. 36, Issue 6, pp. 312.e1-312.e8, (2018) (PubMed).

Ding, Tang, Fan, Wang, Wu, Xu, Xu, Gao, Wu: "Overexpression of PEAK1 contributes to epithelial-mesenchymal transition and tumor metastasis in lung cancer through modulating ERK1/2 and JAK2 signaling." in: Cell death & disease, Vol. 9, Issue 8, pp. 802, (2018) (PubMed).

Ren, Qiu, Lü, Ru, Li, Xiang, Yu, Zhang: "TALENs-directed knockout of the full-length transcription factor Nrf1α that represses malignant behaviour of human hepatocellular carcinoma (HepG2) cells." in: Scientific reports, Vol. 6, pp. 23775, (2017) (PubMed).

Li, Shen, Wang, Li, Wang, Jiang, Zhou, Feng: "EGCG regulates the cross-talk between JWA and topoisomerase IIα in non-small-cell lung cancer (NSCLC) cells." in: Scientific reports, Vol. 5, pp. 11009, (2016) (PubMed).

Mei, Xiang, Cong, Zhang, Li, Yi, Park, Han, Wu, Yu: "Claudin-3 is required for modulation of paracellular permeability by TNF-α through ERK1/2/slug signaling axis in submandibular gland." in: Cellular signalling, Vol. 27, Issue 10, pp. 1915-27, (2016) (PubMed).

Lolli, Narcisi, Lambertini, Penolazzi, Angelozzi, Kops, Gasparini, van Osch, Piva: "Silencing of Antichondrogenic MicroRNA-221 in Human Mesenchymal Stem Cells Promotes Cartilage Repair In Vivo." in: Stem cells (Dayton, Ohio), Vol. 34, Issue 7, pp. 1801-11, (2016) (PubMed).

Piva, Lambertini, Manferdini, Capanni, Penolazzi, Gabusi, Paolella, Lolli, Angelozzi, Lattanzi, Lisignoli: "Slug transcription factor and nuclear Lamin B1 are upregulated in osteoarthritic chondrocytes." in: Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society, Vol. 23, Issue 7, pp. 1226-30, (2015) (PubMed).

Carpenter, Paw, Dewhirst, Lo: "Akt phosphorylates and activates HSF-1 independent of heat shock, leading to Slug overexpression and epithelial-mesenchymal transition (EMT) of HER2-overexpressing breast cancer cells." in: Oncogene, Vol. 34, Issue 5, pp. 546-57, (2015) (PubMed).

Liang, Wang, Li, Yu, Zhang, Li: "miR-33a suppresses the nuclear translocation of ?-catenin to enhance gemcitabine sensitivity in human pancreatic cancer cells." in: Tumour biology, (2015) (PubMed).

Huo, Kao, Chuu: "Androgen receptor inhibits epithelial-mesenchymal transition, migration, and invasion of PC-3 prostate cancer cells." in: Cancer letters, Vol. 369, Issue 1, pp. 103-11, (2015) (PubMed).

Aliases for SLUG Antibodies

snail family transcriptional repressor 2 (Snai2) Antibodies
snail family zinc finger 2 (Snai2) Antibodies
Slug Antibodies
Slugh Antibodies
Snail2 Antibodies
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