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Details for Product No. ABIN969414

SRY (Sex Determining Region Y)-Box 2 (SOX2) antibody

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Antigen
Synonyms ANOP3, MCOPS3, RGD1565646, Qsox, rSOx, Qscn6, Sox-2, cb236, wu:fb83g04, wu:fc14d07, zgc:65860, zgc:77389, SRY-box2, Xsox-2, anop3, mcops3, sox-2
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
Pubmed 3 references available
Catalog no. ABIN969414
Quantity 100 µL
Price
363.00 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 3 to 4 Business Days
Immunogen Purified recombinant fragment of human SOX2 expressed in E. coli.
Clone 10F10
Isotype IgG1
Purification Ascites
Alternative Name SOX2
Background Synonyms:
lcc, ysb, Sox-2, Sox2
Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.
Molecular Weight 34 kDa
Gene ID 20674
Research Area Embryogenesis, Embryonic stem cells, Reproduction, Transcription Factors, Neural Stem Cell marker
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, ICC: 1/200 - 1/1000
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Product cited in: Tay, Zhang, Thomson et al.: "MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation." in: Nature, Vol. 455, Issue 7216, pp. 1124-8, 2008 (PubMed).

Qin, Gan, Shao et al.: "Mouse meningiocytes express Sox2 and yield high efficiency of chimeras after nuclear reprogramming with exogenous factors." in: The Journal of biological chemistry, Vol. 283, Issue 48, pp. 33730-5, 2008 (PubMed).

Dabdoub, Puligilla, Jones et al.: "Sox2 signaling in prosensory domain specification and subsequent hair cell differentiation in the developing cochlea." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 47, pp. 18396-401, 2008 (PubMed).

Alternatives for antigen "SRY (Sex Determining Region Y)-Box 2 (SOX2)", type "Antibodies"
Hosts (126), (29), (4)
Reactivities (145), (61), (40), (22), (21), (20), (17), (12), (6), (5), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1)
Applications (117), (45), (37), (27), (21), (17), (12), (11), (10), (5), (4), (1)
Conjugates (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (27), (6), (6), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1)
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