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SRY (Sex Determining Region Y)-Box 2 (SOX2) antibody

Details for Product No. ABIN969414
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Antigen
Synonyms ANOP3, MCOPS3, RGD1565646, Qsox, rSOx, Qscn6, Sox-2, cb236, wu:fb83g04, wu:fc14d07, zgc:65860, zgc:77389, SRY-box2, Xsox-2, anop3, mcops3, sox-2
Reactivity
Human
(184), (65), (44), (21), (20), (20), (16), (12), (5), (4), (4), (4), (2), (2), (1), (1), (1)
Host
Mouse
(154), (38), (5)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(8), (6), (6), (6), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
(139), (72), (36), (32), (30), (29), (26), (18), (10), (7), (2), (1), (1)
Pubmed 3 references available
Quantity 100 µL
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Shipping to United States (Change)
Availability Will be delivered in 3 to 4 Business Days
Catalog No. ABIN969414
363.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Purified recombinant fragment of human SOX2 expressed in E. coli.
Clone 10F10
Isotype IgG1
Purification Ascites
Alternative Name SOX2
Background Synonyms:
lcc, ysb, Sox-2, Sox2
Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.
Molecular Weight 34 kDa
Gene ID 20674
Research Area Embryogenesis, Embryonic stem cells, Reproduction, Transcription Factors, Neural Stem Cell marker
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, ICC: 1/200 - 1/1000
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Supplier Images
anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) antibody anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) antibody
anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) antibody (2) Figure 2: Immunofluorescence analysis of NTERA-2 cells using SOX2 mouse mAb (green) . Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) antibody (3) Figure 3: Immunohistochemical analysis of paraffin-embedded lung cancer tissues (left) and esophageal cancer tissues (right) using SOX2 mouse mAb with DAB staining.
anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) antibody (4) Figure 1: Western blot analysis using SOX2 mAb against HEK293 (1) and SOX2 (AA: 2-317) -hIgGFc transfected HEK293 (2) cell lysate.
Product cited in: Tay, Zhang, Thomson et al.: "MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation." in: Nature, Vol. 455, Issue 7216, pp. 1124-8, 2008 (PubMed).

Qin, Gan, Shao et al.: "Mouse meningiocytes express Sox2 and yield high efficiency of chimeras after nuclear reprogramming with exogenous factors." in: The Journal of biological chemistry, Vol. 283, Issue 48, pp. 33730-5, 2008 (PubMed).

Dabdoub, Puligilla, Jones et al.: "Sox2 signaling in prosensory domain specification and subsequent hair cell differentiation in the developing cochlea." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 47, pp. 18396-401, 2008 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN969414
363.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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