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SOX2 Products

(SRY (Sex Determining Region Y)-Box 2 (SOX2))
This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq, Jul 2008].

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Featured SOX2 Categories

SOX2 Antibodies

High quality antibodies with extensive validation data.

SOX2 ELISA Kits

Reliable ELISA kits for a wide range of species.

SOX2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SOX2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application CUT&RUN, FACS, ICC, IF, IHC (p), IP, WB
Validations
  • (11)
  • (15)
  • (1)
Cat. No. ABIN2855074
Quantity 100 μL
Datasheet Datasheet
Reactivity Goat, Human, Mouse, Rat
Application ELISA, FACS, ICC, IF (cc), IF (p), IHC (fro), IHC (p), WB
Validations
  • (8)
  • (6)
Cat. No. ABIN669621
Quantity 100 μL
Datasheet Datasheet

Application IHC, WB
Validations
  • (2)
  • (9)
Cat. No. ABIN2777428
Quantity 100 μL
Datasheet Datasheet

Recommended SOX2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Semi-Quantitative DNA-Binding ELISA
Validations
  • (2)
Cat. No. ABIN5526732
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970417
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970418
Quantity 96 tests
Datasheet Datasheet

Recommended SOX2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
  • (1)
Cat. No. ABIN2732450
Quantity 20 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3134199
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN5710406
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our SOX2 products

Lenz, Konecna, Tichy, Machacova, Fiala, Hurnik, Kyllar: "Unique expression patterns of the embryonal stem cell marker SOX2 and hormone receptors suggest the existence of a subpopulation of epithelial stem/progenitor cells in porcine and bovine endometrium." in: Veterinary medicine and science, (2022) (PubMed).

Pagin, Pernebrink, Giubbolini, Barone, Sambruni, Zhu, Chiara, Ottolenghi, Pavesi, Wei, Cantù, Nicolis: "Sox2 controls neural stem cell self-renewal through a Fos-centered gene regulatory network." in: Stem cells (Dayton, Ohio), (2021) (PubMed).

Pagin, Pernebrink, Pitasi, Malighetti, Ngan, Ottolenghi, Pavesi, Cantù, Nicolis: "FOS Rescues Neuronal Differentiation of Sox2-Deleted Neural Stem Cells by Genome-Wide Regulation of Common SOX2 and AP1(FOS-JUN) Target Genes." in: Cells, Vol. 10, Issue 7, (2021) (PubMed).

Chiu, Wu, Kuo, Miao, Zheng, Chen, Lin, Chang, Wang, Chou: "Critical role of SOX2-IGF2 signaling in aggressiveness of bladder cancer." in: Scientific reports, Vol. 10, Issue 1, pp. 8261, (2020) (PubMed).

Li, Sun, Zhao, An, Zhang, Gu, Zhao, Wang, Liu: "Function of BMP4 in the Formation of Vasculogenic Mimicry in Hepatocellular Carcinoma." in: Journal of Cancer, Vol. 11, Issue 9, pp. 2560-2571, (2020) (PubMed).

Zhao, Cai, Liu, Su, An, Moon, Lyu, Si, Chen, Lu: "lncRNA 5430416N02Rik Promotes the Proliferation of Mouse Embryonic Stem Cells by Activating Mid1 Expression through 3D Chromatin Architecture." in: Stem cell reports, Vol. 14, Issue 3, pp. 493-505, (2020) (PubMed).

Hsu, Liu, Lin, Hsu, Hsu, Li, Hung: "Involvement of collagen XVII in pluripotency gene expression and metabolic reprogramming of lung cancer stem cells." in: Journal of biomedical science, Vol. 27, Issue 1, pp. 5, (2020) (PubMed).

Klein, Günther, Kwok, Edenhofer, Üçeyler et al.: "Generation of the human induced pluripotent stem cell line (UKWNLi001-A) from skin fibroblasts of a woman with Fabry disease carrying the X-chromosomal heterozygous c.708 G > C (W236C) missense ..." in: Stem cell research, Vol. 31, pp. 222-226, (2019) (PubMed).

Li, Baskfield, Lin, Beers, Zou, Liu, Jaffré, Roberts, Ottinger, Kontaridis, Zheng: "Generation of an induced pluripotent stem cell line (TRNDi003-A) from a Noonan syndrome with multiple lentigines (NSML) patient carrying a p.Q510P mutation in the PTPN11 gene." in: Stem cell research, Vol. 34, pp. 101374, (2019) (PubMed).

Li, Pradhan, Xu, Baskfield, Farkhondeh, Cheng, Beers, Zou, Liu, Might, Rodems, Zheng: "Generation of an induced pluripotent stem cell line (TRNDi002-B) from a patient carrying compound heterozygous p.Q208X and p.G310G mutations in the NGLY1 gene." in: Stem cell research, Vol. 34, pp. 101362, (2019) (PubMed).

Synonyms and alternative names related to SOX2

SRY-box 2 (SOX2), SRY box 2 (Sox2), SRY (sex determining region Y)-box 2 (Sox2), SRY (sex determining region Y)-box 2 (sox2), SRY-box 2 S homeolog (sox2.S), SRY-box 2 (Sox2), ANOP3, anop3, cb236, lcc, MCOPS3, mcops3, RGD1565646, Sox-2, sox-2, SRY-box2, wu:fb83g04, wu:fc14d07, Xsox-2, ysb, zgc:65860, zgc:77389

Protein level used designations for SOX2

  • SRY-related HMG-box gene 2
  • transcription factor SOX-2
  • transcription factor SOX2
  • SRY-box containing gene 2
  • SRY-box 2
  • SRY-related HMG-box 2
  • sex determining region Y-box 2
  • SRY (sex determining region Y)-box 2
  • soxp
  • transcription factor Sox-2
  • XSox2
  • XlSOX-2
  • sex-determining region Y-box 2
  • Sox2 transcription factor
  • cSox2
  • delta EF2a
  • LOW QUALITY PROTEIN: transcription factor SOX-2
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