Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all synonyms
Select your origin of interest
MiR (show MLXIP Proteins)-335 and miR (show MLXIP Proteins)-34a can also regulate GC cell growth, apoptosis, and invasion at least partly through survivin.
Reduced levels of survivin can sensitize tumor cells to apoptosis.
Inhibition of survivin by YM155 overcomes statin resistance in renal cancer cells.
Data show that knockdown of signal transducer and activator of transcription (show STAT1 Proteins) (STAT3 (show STAT3 Proteins))- significantly inhibited the mRNA and protein levels of survivin.
High survivin expression is associated with gastric cancer.
survivin may have a role in radioresistance of laryngeal squamous cell carcinoma
High survivin expression is associated with radioresistance in HER2 (show ERBB2 Proteins)-positive breast cancers.
the blockade of survivin will allow for the treatment of glioblastoma, partially attributing to the inhibition of EGFR (show EGFR Proteins) and MMP9 (show MMP9 Proteins) expression.
Mi335 might function as a tumor suppressor in osteosarcoma(OS), and downregulation of miR (show MLXIP Proteins)-335 in OS cells contributes to the decreased apoptotic potential of OS cells through derepression of survivin.
results suggest that high-grade glioma expressing high level of alpha5beta1 integrin may benefit from associated therapies including integrin antagonists and repressors of survivin expression.
Survivin is important for optimal development of bovine blastocysts and confirm that survivin expression suppresses apoptosis of pre-implantation embryos.
Dermatoplasty can decrease spermatogenic cells and reduce Survivin protein expression.
Report survivin expression in the normal pancreas.
Survivin is a key regulator of gut (show GUSB Proteins) tissue integrity by regulating epithelial homeostasis in the stem cell niche.
TGFbetaRI inhibition in an injured adult heart could both stimulate the autocrine/paracrine activity of survivin and inhibit Wnt (show WNT2 Proteins) in CPCs to mediate cardioprotection and improve cardiac function.
Survivin is a key gene for regulating squamous cell carcinoma (SCC (show CYP11A1 Proteins)) cancer stem cell formation and cancer SCC (show CYP11A1 Proteins) development.
In colorectal cancer mice with downregulated expression of survivin, there were higher numbers of apoptotic cells and decreased expression levels of bcl2 (show BCL2 Proteins) and ki67 (show MKI67 Proteins).
survivin is essential for B cell division but does not affect survival of naive B cells. Survival of proliferating B cells may be impacted indirectly by survivin deficiency because of increased genotoxic stress caused by failed chromosomal segregation.
Survivin directly participates in PRL (show PRL Proteins)-mediated beta cell proliferation via Akt (show AKT1 Proteins), STAT5 (show STAT5A Proteins)-PIM (show PIM1 Proteins) and ERK (show EPHB2 Proteins) signalling pathways during pregnancy
Studied competitive inhibition of survivin using a cell-permeable recombinant protein induces cancer-specific apoptosis in colon cancer model.
Results suggest a role for survivin in regulating adult neural precursor activity and inhibiting apoptosis or programmed cell death in the dentate gyrus following brain injury
NR4A1 (show NR4A1 Proteins) protects pancreatic beta-cells against endoplasmic reticulum stress-mediated apoptosis by up-regulating Survivin expression and down-regulating CHOP (show DDIT3 Proteins) expression.
Studies indicate the importance of survivin in Sonic hedgehog (SHH (show SHH Proteins))-driven medulloblastoma (MB).
This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
baculoviral IAP repeat-containing 5 (survivin)
, baculoviral IAP repeat-containing protein 5
, baculoviral IAP repeat-containing 5 (survivin)-like
, apoptosis inhibitor survivin
, baculoviral IAP repeat-containing 5
, apoptosis inhibitor 4
, survivin variant 3 alpha