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Browse our anti-PARP1 (PARP1) Antibodies

Full name:
anti-Poly (ADP-Ribose) Polymerase 1 Antibodies (PARP1)
On www.antibodies-online.com are 427 Poly (ADP-Ribose) Polymerase 1 (PARP1) Antibodies from 30 different suppliers available. Additionally we are shipping PARP1 Kits (32) and PARP1 Proteins (25) and many more products for this protein. A total of 512 PARP1 products are currently listed.
Synonyms:
5830444G22Rik, Adprp, Adprt, ADPRT 1, Adprt1, AI893648, ARTD1, BEST:LD21673, C80510, CG17685, CG17696, CG17718, CG40411, D.PARP, Dm.pARTa, Dmel\\CG40411, dPARP, LD21673.3prime, padprt-1, parp, parp-1, PARP1, ppol, sPARP-1
list all antibodies Gene Name GeneID UniProt
PARP1 142 P09874
PARP1 25591 P27008
PARP1 11545  

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anti-Human PARP1 Antibodies:

anti-Rat (Rattus) PARP1 Antibodies:

anti-Mouse (Murine) PARP1 Antibodies:

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Top referenced anti-PARP1 Antibodies

  1. Human Polyclonal PARP1 Primary Antibody for IP, IHC - ABIN2854261 : Lamarre, Talbot, de Murcia, Laplante, Leduc, Mazen, Poirier: Structural and functional analysis of poly(ADP ribose) polymerase: an immunological study. in Biochimica et biophysica acta 1988 (PubMed)
    Show all 8 references for ABIN2854261

  2. Human Monoclonal PARP1 Primary Antibody for IF, WB - ABIN394297 : Lee, Bang, Park, Kim, Shin, Bae: Lack of association between poly(ADP-ribose) polymerase (PARP) polymorphisms and rheumatoid arthritis in a Korean population. in Rheumatology international 2012 (PubMed)
    Show all 5 references for ABIN394297

  3. Human Polyclonal PARP1 Primary Antibody for WB - ABIN1881628 : Dong, Bey, Li, Kabbani, Yan, Xie, Hsieh, Gao, Boothman: Prostate cancer radiosensitization through poly(ADP-Ribose) polymerase-1 hyperactivation. in Cancer research 2010 (PubMed)
    Show all 4 references for ABIN1881628

  4. Human Polyclonal PARP1 Primary Antibody for WB - ABIN1881627 : Krishnakumar, Kraus: PARP-1 regulates chromatin structure and transcription through a KDM5B-dependent pathway. in Molecular cell 2010 (PubMed)
    Show all 4 references for ABIN1881627

  5. Human Polyclonal PARP1 Primary Antibody for EIA, WB - ABIN358977 : Tao, Gao, Hoffman, Liu: Domain C of human poly(ADP-ribose) polymerase-1 is important for enzyme activity and contains a novel zinc-ribbon motif. in Biochemistry 2008 (PubMed)
    Show all 2 references for ABIN358977

  6. Human Polyclonal PARP1 Primary Antibody for ChIP, WB - ABIN2668274 : Kim, Mauro, Gévry, Lis, Kraus: NAD+-dependent modulation of chromatin structure and transcription by nucleosome binding properties of PARP-1. in Cell 2004 (PubMed)
    Show all 2 references for ABIN2668274

  7. Human Polyclonal PARP1 Primary Antibody for ChIP, WB - ABIN2668275 : Ratnakumar, Duarte, LeRoy, Hasson, Smeets, Vardabasso, Bönisch, Zeng, Xiang, Zhang, Li, Wang, Hake, Schermelleh, Garcia, Bernstein: ATRX-mediated chromatin association of histone variant macroH2A1 regulates ?-globin expression. in Genes & development 2012 (PubMed)

  8. Human Polyclonal PARP1 Primary Antibody for IF (p), IHC (p) - ABIN677903 : Ma, Liu, Wang, Liu, Chen, Valle, Zuo, Xia, Liu: Crucial Role of Lateral Size for Graphene Oxide in Activating Macrophages and Stimulating Pro-inflammatory Responses in Cells and Animals. in ACS nano 2015 (PubMed)

  9. Chicken Polyclonal PARP1 Primary Antibody for WB - ABIN2778108 : Pétrilli, Herceg, Hassa, Patel, Di Paola, Cortes, Dugo, Filipe, Thiemermann, Hottiger, Cuzzocrea, Wang: Noncleavable poly(ADP-ribose) polymerase-1 regulates the inflammation response in mice. in The Journal of clinical investigation 2004 (PubMed)

More Antibodies against PARP1 Interaction Partners

Fruit Fly (Drosophila melanogaster) Poly (ADP-Ribose) Polymerase 1 (PARP1) interaction partners

  1. chromatin loosening and associated initiation of gene expression is activated by phosphorylation of H2Av (show H2AFV Antibodies) in a nucleosome positioned in promoter regions of PARP-1-dependent genes

  2. Based on these findings, we propose a model that explains how PARP1 activity impacts nucleolar functions and, consequently, ribosomal biogenesis

  3. PARP is associated with the 5' end of Hsp70, and its enzymatic activity is rapidly induced by heat shock leading to nucleosome loss.

  4. Activation of PARP-1 overexpression in the imago results in extension of the lifespan in females and males. The lifespan increase in females with PARP-1 conditional overexpression was accompanied by decrease of fertility.

  5. PARP1 is targeted to chromatin by association with the histone H2A variant (H2Av).

  6. demonstrate that this alteration specifically excludes PARP1 protein from heterochromatin and makes PARP1 unable to maintain repression of retrotransposable elements.

  7. PARP-e autoregulates Parp transcription

  8. propose that chromosomal PARP molecules become activated by developmental or environmental cues and strip nearby chromatin proteins off DNA to generate a puff

  9. PARP1 is required for protein targeting to Cajal body.

Human Poly (ADP-Ribose) Polymerase 1 (PARP1) interaction partners

  1. Data show that E7449 represents a dual Poly(ADP-ribose) Polymerase 1/2 and tankyrase 1 (show TNKS Antibodies)/2 inhibitor which has the advantage of targeting Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling addicted tumors.

  2. Non-small cell lung cancer patients with high intra-tumoral PARP1 activity had a poor prognosis.

  3. DNA damage induced necrosis through a PARP1-dependent and p53 (show TP53 Antibodies)-independent pathway.

  4. Data indicate that poly(ADP-ribose) polymerase 1 (PARP1) protein is expressed in pediatric high-grade astrocytomas (pHGA) and diffuse intrinsic pontine gliomas (DIPG) patient samples and cell lines.

  5. The initial affinity between the PARP1, PARP2 (show PARP2 Antibodies) and the DNA damaged site appears to influence both the size of the Poly(ADP-Ribose) synthesized and the time of residence of PARylated PARP1 and PARP2 (show PARP2 Antibodies) on DNA damages.

  6. Our combination strategy could expand the clinical application of PARP (show COL11A2 Antibodies)-inhibitors to non-BRCA mutated cancers and may target a new group of NSCLC patients who show limited response to current therapies.

  7. PARP-1 has an important role in the progression of acute myeloid leukemia (show BCL11A Antibodies) by suppressing the myeloproliferative leukemia virus oncogene (show MPL Antibodies)

  8. Data suggest that inhibition of PARP1 (preferential inhibition of PARP1 over PARP2 (show PARP2 Antibodies)) arrests cell cycle/cell proliferation and promotes apoptosis of breast tumor cells (including triple negative breast tumor cells).

  9. Activation of the PI3K (show PIK3CA Antibodies)/mTOR (show FRAP1 Antibodies) Pathway following PARP (show COL11A2 Antibodies) Inhibition in Small Cell Lung Cancer.

  10. Noncovalent binding of ADP-ribose polymers with TET1 (show TET1 Antibodies) catalytic domain decreases TET1 (show TET1 Antibodies) hydroxylase activity while the covalent PARylation stimulates TET1 (show TET1 Antibodies) enzyme. In addition, TET1 (show TET1 Antibodies) activates PARP-1/ARTD1 independently of DNA breaks.

Cow (Bovine) Poly (ADP-Ribose) Polymerase 1 (PARP1) interaction partners

  1. ADPRT Val762Ala and APE1 (show APEX1 Antibodies) Asp148Glu polymorphisms are not associated with increased breast cancer risk

  2. analysis of poly(ADP-ribose) polymerase 1 interaction with apurinic/apyrimidinic sites

  3. FGF2 (show FGF2 Antibodies) stimulates poly(ADP-ribose) polymerase activity by a DNA strand breaks-independent manner which involves a mitogen-activated protein kinases (MAPK (show MAPK1 Antibodies))-dependent pathway

Mouse (Murine) Poly (ADP-Ribose) Polymerase 1 (PARP1) interaction partners

  1. By enhancing PARP1 activity, ULK1 (show ULK1 Antibodies) contributes to ATP depletion and death of H2O2-treated cells.

  2. PARP-1 deficiency significantly increased the chromatin binding affinity of MeCP2 (show MECP2 Antibodies) in vivo.

  3. these results identify CHD1L (show CHD1L Antibodies) as a key chromatin remodeler involved in PARP1/PARylation-regulated early-stage reprogramming and pluripotency in stem cells.

  4. PARP-1 activation is required for the consolidation, reconsolidation, and extinction of contextual fear memory

  5. Suggest role for LRP1 (show LRP1 Antibodies)/PARP1 signaling in endothelial cell proliferation and retinal neovascularization induced by hypoxia.

  6. Matrix Metalloproteinase-2 (MMP-2 (show MMP2 Antibodies)) Gene Deletion Enhances MMP-9 (show MMP9 Antibodies) Activity, Impairs PARP-1 Degradation, and Exacerbates Hepatic Ischemia and Reperfusion Injury in Mice

  7. PARP-1 inhibition blocks glioma conditioned medium-induced endothelial migration by interfering with ERK (show EPHB2 Antibodies) signal-transduction pathway.

  8. The results demonstrate that ARTD1 modulates IL-6 expression by regulating the function of an NF-kappaB enhanceosome complex, which involves MLL1 and does not require ADP-ribosylation.

  9. Results show the stimulatory effect of PARP-1 on APE1 (show APEX1 Antibodies)-dependent base excision repair (BER). PARP-1 and APE1 (show APEX1 Antibodies) appear to have a functional interaction in BER since PARP-1 can stimulate the strand incision activity of APE1 (show APEX1 Antibodies).

  10. PARP-1 and -2 play a role in cancer-induced cachexia, thus selective pharmacological inhibition of PARP-1 and -2 may be of interest in clinical settings

PARP1 Antigen Profile

Antigen Summary

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

Alternative names and synonyms associated with PARP1

  • Poly-(ADP-ribose) polymerase (Parp) antibody
  • poly (ADP-ribose) polymerase 1 (PARP1) antibody
  • poly (ADP-ribose) polymerase 1 (Parp1) antibody
  • poly (ADP-ribose) polymerase 1 (parp1) antibody
  • poly (ADP-ribose) polymerase family, member 1 (Parp1) antibody
  • poly ADP-ribose polymerase (Parp) antibody
  • 5830444G22Rik antibody
  • Adprp antibody
  • Adprt antibody
  • ADPRT 1 antibody
  • Adprt1 antibody
  • AI893648 antibody
  • ARTD1 antibody
  • BEST:LD21673 antibody
  • C80510 antibody
  • CG17685 antibody
  • CG17696 antibody
  • CG17718 antibody
  • CG40411 antibody
  • D.PARP antibody
  • Dm.pARTa antibody
  • Dmel\\CG40411 antibody
  • dPARP antibody
  • LD21673.3prime antibody
  • padprt-1 antibody
  • parp antibody
  • parp-1 antibody
  • PARP1 antibody
  • ppol antibody
  • sPARP-1 antibody

Protein level used designations for PARP1

CG40411-PB , CG40411-PC , Parp-PB , Parp-PC , Poly(ADP ribose) polymerase 1 , Poly(ADP)-Ribose polymerase , Poly(ADP-)Ribose polymerase , Poly(ADP-ribose) polymerase , Poly(ADP-ribose) polymerase 1 , ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) , ADP-ribosyltransferase NAD(+) , ADP-ribosyltransferase diphtheria toxin-like 1 , NAD(+) ADP-ribosyltransferase 1 , poly (ADP-ribose) polymerase family, member 1 , poly [ADP-ribose] polymerase 1 , poly(ADP-ribose) polymerase , poly(ADP-ribose) synthetase , poly(ADP-ribosyl)transferase , poly[ADP-ribose] synthase 1 , ADP-ribosyltransferase (NAD+ , ADP-ribosyltransferase 1 , ADPRT 1 , poly (ADP-ribose) polymerase) , poly(ADP-ribose) polymerase PARP-1 , poly[ADP-ribose] synthetase 1 , ADP-ribosyltransferase (NAD+) poly (ADP-ribose) polymerase) , PARP-1 , ADP-ribosyltransferase (NAD+, poly (ADP-ribose) polymerase) 1 , ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) 1 , msPARP , Poly[ADP-ribose] synthase 1

GENE ID SPECIES
3355109 Drosophila melanogaster
142 Homo sapiens
25591 Rattus norvegicus
286764 Bos taurus
397928 Xenopus laevis
396199 Gallus gallus
490385 Canis lupus familiaris
11545 Mus musculus
100689463 Cricetulus griseus
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