PARP1 Products
(Poly (ADP-Ribose) Polymerase 1 (PARP1))
Categories
This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008].
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Featured PARP1 Categories
PARP1 Antibodies
High quality antibodies with extensive validation data.
PARP1 ELISA Kits
Reliable ELISA kits for a wide range of species.
PARP1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PARP1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IP, IF, IHC (p), ICC, ChIP
Validations
- (7)
- (17)
Cat. No.
ABIN2854798
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, IF
Validations
- (2)
- (8)
Cat. No.
ABIN6145232
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IF, IHC (p)
Validations
- (7)
Cat. No.
ABIN7208149
Quantity
100 μL
Datasheet
Datasheet
Recommended PARP1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969442
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969441
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958679
Quantity
96 tests
Datasheet
Datasheet
Recommended PARP1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Baculovirus
Validations
- (2)
- (3)
Cat. No.
ABIN1741729
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (2)
Cat. No.
ABIN5624620
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Baculovirus
Validations
- (1)
- (2)
Cat. No.
ABIN1741730
Quantity
5 μg
Datasheet
Datasheet
Latest Publications for our PARP1 products
: "Enhancing the antitumor activity of an engineered TRAIL-coated oncolytic adenovirus for treating acute myeloid leukemia." in: Signal transduction and targeted therapy, Vol. 5, Issue 1, pp. 40, (2020) (PubMed).: "Role of Poly [ADP-ribose] Polymerase 1 in Activating the Kirstenras (KRAS) Gene in Response to Oxidative Stress." in: International journal of molecular sciences, Vol. 21, Issue 17, (2020) (PubMed).
: "Biological effects of whole Z.Officinale extract on chronic myeloid leukemia cell line K562." in: Gene, Vol. 692, pp. 217-222, (2019) (PubMed).
: "The inhibition of Bax activation-induced apoptosis by RasGRP2 via R-Ras-PI3K-Akt signaling pathway in the endothelial cells." in: Scientific reports, Vol. 9, Issue 1, pp. 16717, (2019) (PubMed).
: "Genetic and Epigenetic Perturbations by DNMT3A-R882 Mutants Impaired Apoptosis through Augmentation of PRDX2 in Myeloid Leukemia Cells." in: Neoplasia (New York, N.Y.), Vol. 20, Issue 11, pp. 1106-1120, (2019) (PubMed).
: "Neuronal sphingosine kinase 2 subcellular localization is altered in Alzheimer's disease brain." in: Acta neuropathologica communications, Vol. 6, Issue 1, pp. 25, (2019) (PubMed).
: "Upregulation of CISD2 augments ROS homeostasis and contributes to tumorigenesis and poor prognosis of lung adenocarcinoma." in: Scientific reports, Vol. 7, Issue 1, pp. 11893, (2019) (PubMed).
: "Oligo-Porphyran Ameliorates Neurobehavioral Deficits in Parkinsonian Mice by Regulating the PI3K/Akt/Bcl-2 Pathway." in: Marine drugs, Vol. 16, Issue 3, (2018) (PubMed).
: "Glutathione disulfide sensitizes hepatocytes to TNFα-mediated cytotoxicity via IKK-β S-glutathionylation: a potential mechanism underlying non-alcoholic fatty liver disease." in: Experimental & molecular medicine, Vol. 50, Issue 4, pp. 7, (2018) (PubMed).
: "Epigallocatechin-3-Gallate Ameliorates Glucocorticoid-Induced Osteoporosis of Rats in Vivo and in Vitro." in: Frontiers in pharmacology, Vol. 9, pp. 447, (2018) (PubMed).
Synonyms and alternative names related to PARP1
poly(ADP-ribose) polymerase 1 (PARP1), poly (ADP-ribose) polymerase 1 (Parp1), poly (ADP-ribose) polymerase family, member 1 (Parp1), Poly-(ADP-ribose) polymerase (Parp), poly(ADP-ribose) polymerase 1 L homeolog (parp1.L), poly (ADP-ribose) polymerase 1 (PARP1), poly(ADP-ribose) polymerase 1 (Parp1), poly (ADP-ribose) polymerase 1 (parp1), 5830444G22Rik, Adprp, ADPRT, Adprt, ADPRT 1, ADPRT1, Adprt1, adprt1, AI893648, ARTD1, BEST:LD21673, C80510, CG17685, CG17696, CG17718, CG40411, D.PARP, Dm.pARTa, Dmel\\CG40411, dPARP, LD21673.3prime, pADPRT-1, padprt-1, PARP, parp, PARP-1, Parp-1, parp-1, PARP1, PPOL, ppol, si:dkey-206f10.3, sPARP-1, wu:fc60f12, zgc:110092Protein level used designations for PARP1
- ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)
- ADP-ribosyltransferase NAD(+)
- ADP-ribosyltransferase diphtheria toxin-like 1
- NAD(+) ADP-ribosyltransferase 1
- poly (ADP-ribose) polymerase family, member 1
- poly [ADP-ribose] polymerase 1
- poly(ADP-ribose) polymerase
- poly(ADP-ribose) synthetase
- poly(ADP-ribosyl)transferase
- poly[ADP-ribose] synthase 1
- ADP-ribosyltransferase (NAD+
- ADP-ribosyltransferase 1
- ADPRT 1
- poly (ADP-ribose) polymerase)
- poly(ADP-ribose) polymerase PARP-1
- poly[ADP-ribose] synthetase 1
- ADP-ribosyltransferase (NAD+, poly (ADP-ribose) polymerase) 1
- ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) 1
- msPARP
- CG40411-PB
- CG40411-PC
- Parp-PB
- Parp-PC
- Poly(ADP ribose) polymerase 1
- Poly(ADP)-Ribose polymerase
- Poly(ADP-)Ribose polymerase
- Poly(ADP-ribose) polymerase
- Poly(ADP-ribose) polymerase 1
- PARP-1
- ADP-ribosyltransferase (NAD+) poly (ADP-ribose) polymerase)
- Poly[ADP-ribose] synthase 1
- LOW QUALITY PROTEIN: poly [ADP-ribose] polymerase 1
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