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PARP1 antibody (AA 183-214)

PARP1 Reactivity: Human FACS, IF, ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3032164
$578.58
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  • Target See all PARP1 Antibodies
    PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))
    Binding Specificity
    • 23
    • 18
    • 16
    • 15
    • 15
    • 13
    • 11
    • 11
    • 10
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 8
    • 8
    • 8
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 183-214
    Reactivity
    • 259
    • 76
    • 60
    • 15
    • 12
    • 10
    • 7
    • 6
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 246
    • 33
    • 1
    • 1
    Rabbit
    Clonality
    • 241
    • 40
    Polyclonal
    Conjugate
    • 160
    • 18
    • 17
    • 15
    • 15
    • 14
    • 14
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    This PARP1 antibody is un-conjugated
    Application
    • 163
    • 157
    • 78
    • 35
    • 32
    • 30
    • 27
    • 27
    • 24
    • 17
    • 14
    • 8
    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF), ELISA, Western Blotting (WB)
    Cross-Reactivity (Details)
    Expected species reactivity: Mouse
    Purification
    Purified
    Immunogen
    A portion of amino acids 183-214 from the human protein was used as the immunogen for this PARP antibody.
    Isotype
    Ig Fraction
  • Application Notes
    Titration of the PARP antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:10-1:50,Flow Cytometry: 1:10-1:50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS pH 7.4 with 0.09 % sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the PARP antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))
    Alternative Name
    PARP (PARP1 Products)
    Synonyms
    ADPRT antibody, ADPRT 1 antibody, ADPRT1 antibody, ARTD1 antibody, PARP antibody, PARP-1 antibody, PPOL antibody, pADPRT-1 antibody, Adprt antibody, Parp-1 antibody, 5830444G22Rik antibody, AI893648 antibody, Adprp antibody, Adprt1 antibody, C80510 antibody, parp-1 antibody, sPARP-1 antibody, BEST:LD21673 antibody, CG17685 antibody, CG17696 antibody, CG17718 antibody, CG40411 antibody, D.PARP antibody, Dm.pARTa antibody, Dmel\\CG40411 antibody, LD21673.3prime antibody, PARP1 antibody, dPARP antibody, parp antibody, adprt1 antibody, padprt-1 antibody, ppol antibody, si:dkey-206f10.3 antibody, wu:fc60f12 antibody, zgc:110092 antibody, poly(ADP-ribose) polymerase 1 antibody, poly (ADP-ribose) polymerase 1 antibody, poly (ADP-ribose) polymerase family, member 1 antibody, Poly-(ADP-ribose) polymerase antibody, poly(ADP-ribose) polymerase 1 L homeolog antibody, PARP1 antibody, Parp1 antibody, Parp antibody, parp1.L antibody, parp1 antibody
    Background
    PARP is a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
    UniProt
    P09874
    Pathways
    Apoptosis, Caspase Cascade in Apoptosis, DNA Damage Repair, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location
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