Browse our anti-TNFSF10 (TNFSF10) Antibodies

Full name:
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 10 Antibodies (TNFSF10)
On www.antibodies-online.com are 366 Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) Antibodies from 34 different suppliers available. Additionally we are shipping TNFSF10 Proteins (71) and TNFSF10 Kits (47) and many more products for this protein. A total of 503 TNFSF10 products are currently listed.
Synonyms:
A330042I21Rik, AI448571, APO-2L, APO2L, CD253, Ly81, TL2, Trail, trail1, xtrail1
list all antibodies Gene Name GeneID UniProt
TNFSF10 8743 P50591
TNFSF10 22035 P50592
TNFSF10 246775  

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Most Popular Reactivities for anti-TNFSF10 (TNFSF10) Antibodies

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anti-Human TNFSF10 Antibodies:

anti-Mouse (Murine) TNFSF10 Antibodies:

anti-Rat (Rattus) TNFSF10 Antibodies:

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Top referenced anti-TNFSF10 Antibodies

  1. Human Monoclonal TNFSF10 Primary Antibody for IHC (p), WB - ABIN252480 : Müller, Raftery, Kather, Giese, Schönrich: Frontline: Induction of apoptosis and modulation of c-FLIPL and p53 in immature dendritic cells infected with herpes simplex virus. in European journal of immunology 2004 (PubMed)
    Show all 7 references for 252480

  2. Human Monoclonal TNFSF10 Primary Antibody for WB - ABIN967538 : Mariani, Matiba, Armandola, Krammer: Interleukin 1 beta-converting enzyme related proteases/caspases are involved in TRAIL-induced apoptosis of myeloma and leukemia cells. in The Journal of cell biology 1997 (PubMed)
    Show all 6 references for 967538

  3. Human Polyclonal TNFSF10 Primary Antibody for ELISA, IHC (p) - ABIN1996723 : Song, Jin: TRAIL (CD253), a new member of the TNF superfamily. in Journal of biological regulators and homeostatic agents 2005 (PubMed)
    Show all 2 references for 1996723

  4. Human Polyclonal TNFSF10 Primary Antibody for IF (p), IHC (p) - ABIN673494 : Fang, Zhang, Qi, Fan, Luo, Liu, Tan: Evodiamine induces G2/M arrest and apoptosis via mitochondrial and endoplasmic reticulum pathways in H446 and H1688 human small-cell lung cancer cells. in PLoS ONE 2014 (PubMed)
    Show all 2 references for 673494

  5. Dog (Canine) Polyclonal TNFSF10 Primary Antibody for WB - ABIN2792132 : Wu, Tsai, Lin, Chou, Chen, Yang, Hsu, Hsu: Helicobacter pylori enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in human gastric epithelial cells. in World journal of gastroenterology : WJG 2004 (PubMed)
    Show all 2 references for 2792132

  6. Human Polyclonal TNFSF10 Primary Antibody for WB - ABIN151524 : Herzer, Carbow, Sydor, Sowa, Biesterfeld, Hofmann, Galle, Gerken, Canbay: Deficiency of the promyelocytic leukemia protein fosters hepatitis C-associated hepatocarcinogenesis in mice. in PLoS ONE 2012 (PubMed)

  7. Human Monoclonal TNFSF10 Primary Antibody for FACS - ABIN4897836 : Kalb, Glaser, Stary, Koszik, Stingl: TRAIL(+) human plasmacytoid dendritic cells kill tumor cells in vitro: mechanisms of imiquimod- and IFN-?-mediated antitumor reactivity. in Journal of immunology (Baltimore, Md. : 1950) 2012 (PubMed)

  8. Human Monoclonal TNFSF10 Primary Antibody for FACS - ABIN1106154 : Bremer, Samplonius, Peipp, van Genne, Kroesen, Fey, Gramatzki, de Leij, Helfrich: Target cell-restricted apoptosis induction of acute leukemic T cells by a recombinant tumor necrosis factor-related apoptosis-inducing ligand fusion protein with specificity for human CD7. in Cancer research 2005 (PubMed)

  9. Human Polyclonal TNFSF10 Primary Antibody for IF, ELISA - ABIN1533756 : Wiley, Schooley, Smolak, Din, Huang, Nicholl, Sutherland, Smith, Rauch, Smith: Identification and characterization of a new member of the TNF family that induces apoptosis. in Immunity 1996 (PubMed)

More Antibodies against TNFSF10 Interaction Partners

Xenopus laevis Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) interaction partners

  1. xTRAIL1 can cause apoptosis, probably mediated through xDR-Ms, in larval red blood cells, but may not kill adult RBCs, presumably owing to PKC (show PKC Antibodies) activation, as part of the mechanism for RBC (show CACNA1C Antibodies) switching

Human Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) interaction partners

  1. Fn14 (show TNFRSF12A Antibodies).TRAIL can be converted into a highly effective TRAIL oligomer upon binding to TWEAK (show TNFSF12 Antibodies) which induces lymphoblast apoptosis.

  2. BAY61-3606 sensitizes colon cancer cells to TRAIL-induced apoptosis by up-regulating DR4 (show HLADRB4 Antibodies) expression in p53 (show TP53 Antibodies)-dependent manner and inhibiting NF-kappaB (show NFKB1 Antibodies) activity.

  3. High-order TRAIL oligomer formation in TRAIL-coated lipid nanoparticles enhances DR5 (show TNFRSF10B Antibodies) cross-linking and increases antitumour effect against colon cancer cells and xenograft tumors.

  4. results suggest that miR (show MLXIP Antibodies)-223 increases the sensitivity of TNBCSCs to TRAIL-induced apoptosis by targeting HAX-1 (show HAX1 Antibodies)

  5. The results suggested that miR (show MLXIP Antibodies)-138 regulates the interferon (show IFNA Antibodies)-stimulated gene 15 expression by directly targeting the 3' untranslated region of interferon (show IFNA Antibodies)-stimulated gene 15 and modulates the sensitivity to TRAIL-induced apoptosis.

  6. these results demonstrate that high HOTAIR levels increase the resistance of pancreatic cancer cells to TRAIL-induced apoptosis via epigenetic regulation of DR5 (show TNFRSF10B Antibodies) expression.

  7. miR (show MLXIP Antibodies)-661 overexpression sensitized tumors to TRAIL or STS (show STS Antibodies) induced apoptosis in a xenograft mouse model, and these effects were attenuated by co-expression of CYC1 (show CYC1 Antibodies).

  8. sorafenib overcomes TRAIL resistance in renal cell carcinoma (show MOK Antibodies) by a mechanism that does not rely on Mcl-1 (show MCL1 Antibodies) down-regulation but involves ROS (show ROS1 Antibodies) accumulation and increased activation of caspase-8 (show CASP8 Antibodies)

  9. Review: OPG (show TNFRSF11B Antibodies), RANKL (show TNFSF11 Antibodies) and TRAIL are involved in vascular calcification.

  10. results indicate that E2 inhibits VSMCs proliferation and migration by downregulation of TRAIL expression via suppression of NF-kappaB (show NFKB1 Antibodies) pathway.

Pig (Porcine) Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) interaction partners

  1. Data suggest forkhead box protein O1 (FoxO1 (show FOXO1 Antibodies)) involvement in the regulation of TNF-related apoptosis-inducing ligand TRAIL and Fas ligand FasL (show FASL Antibodies) expression during follicular atresia.

  2. The chromosomal location of the porcine TNFSF10 gene was determined by FISH of a specific BAC clone to metaphase chromosomes The chromosomal location of the porcine TNFSF10 gene was determined by FISH of a specific BAC clone to metaphase chromosomes.

Mouse (Murine) Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) interaction partners

  1. Tnfsf10 expression is increased in eosinophilic esophagitis. Tnfsf10(-/-) mice were largely protected from esophageal fibrosis and eosinophilic inflammation.

  2. Diabetes significantly increased OPG (show TNFSF11 Antibodies) and the OPG (show TNFSF11 Antibodies)/TRAIL ratio expression in the aorta, while dyslipidemia was the major determinant of the changes observed in the heart, where it significantly increased OPG (show TNFSF11 Antibodies) and reduced TRAIL expression, thus increasing cardiac OPG (show TNFSF11 Antibodies)/TRAIL ratio.

  3. TRAIL can promote angiogenesis following hindlimb ischemia in vivo via NOX4 (show NOX4 Antibodies)/eNOS (show NOS3 Antibodies)/nitric oxide signaling.

  4. Study reports that loss of the Opg (show TNFSF11 Antibodies) gene results in deterioration of abdominal aortic aneurysms (AAA (show AAAS Antibodies)), possibly through involvement of TRAIL in smooth muscle actin (SMA (show SMN1 Antibodies))-positive cells and myofibroblasts.

  5. PARP1 (show PARP1 Antibodies) acts as a prominent upstream regulator of high mobility group box 1 (show HMGB1 Antibodies)-mediated autophagy and maintains a homeostatic balance between apoptosis and autophagy, which provides new insight into the mechanism of TNFSF10 resistance

  6. Data suggest that Socs3 (suppressor of cytokine signaling 3 (show SOCS3 Antibodies)) plays critical negative role in regulation of Trail expression in endoplasmic reticulum stress in macrophages via Jun N-terminal kinase (show MAPK8 Antibodies)/AP-1 (show JUN Antibodies) transcription factor signaling.

  7. These findings indicate that acute fasting enhances TRAIL-mediated liver natural killer cell activity against neoplastic cells through upregulation of heat shock protein 70 (show HSP70 Antibodies).

  8. These results demonstrated that TRAIL plays a deleterious role in acute kidney injury pathogenesis induced by scald (show RDH11 Antibodies) burns

  9. TRAIL-deficiency in ApoE (show APOE Antibodies)(-/-) mice exacerbates nephropathy and insulin (show INS Antibodies) resistance

  10. Tumor necrosis factor (show TNF Antibodies)-related apoptosis-inducing ligand translates neonatal respiratory infection into chronic lung disease.

TNFSF10 Antigen Profile

Antigen Summary

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with TNFSF10

  • tumor necrosis factor (ligand) superfamily, member 10 (TNFSF10) antibody
  • TNF-related apoptosis inducing ligand-like (TRAIL-LIKE) antibody
  • tumor necrosis factor (ligand) superfamily, member 10 (tnfsf10) antibody
  • tumor necrosis factor (ligand) superfamily, member 10 (Tnfsf10) antibody
  • A330042I21Rik antibody
  • AI448571 antibody
  • APO-2L antibody
  • APO2L antibody
  • CD253 antibody
  • Ly81 antibody
  • TL2 antibody
  • Trail antibody
  • trail1 antibody
  • xtrail1 antibody

Protein level used designations for TNFSF10

tumor necrosis factor ligand superfamily member 10 , TNF-related apoptosis inducing ligand , TNF-related apoptosis inducing ligand-like protein , Tnf-alpha related apoptosis inducing ligand , TNF-related apoptosis-inducing ligand 1 , tumor necrosis factor related apoptosis inducing ligand 1 , Apo-2 ligand , TNF-related apoptosis inducing ligand TRAIL , chemokine tumor necrosis factor ligand superfamily member 10 , tumor necrosis factor (ligand) family, member 10 , tumor necrosis factor apoptosis-inducing ligand splice variant delta , tumor necrosis factor-related apoptosis-inducing ligand , TNF-related apoptosis-inducing ligand , TRAIL/APO2L

GENE ID SPECIES
378894 Gallus gallus
395283 Gallus gallus
100174789 Felis catus
100316914 Xenopus laevis
8743 Homo sapiens
100174780 Canis lupus familiaris
406191 Sus scrofa
22035 Mus musculus
246775 Rattus norvegicus
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