Browse our Adrenergic, beta-1-, Receptor Proteins (ADRB1)

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Adrenergic, beta-1-, Receptor Proteins (ADRB1)
On are 6 Adrenergic, beta-1-, Receptor (ADRB1) Proteins from 2 different suppliers available. Additionally we are shipping Adrenergic, beta-1-, Receptor Antibodies (48) and Adrenergic, beta-1-, Receptor Kits (28) and many more products for this protein. A total of 89 Adrenergic, beta-1-, Receptor products are currently listed.
Adrb-1, ADRB1, ADRB1R, ADRB3, ADRBK1, B1AR, BAR1, beta-AR, BETA1AR, RATB1AR, RHR, X-Beta1AR, zgc:194728, zgc:194731
list all proteins Gene Name GeneID UniProt
ADRB1 11554 P34971
ADRB1 153 P08588
Rat ADRB1 ADRB1 24925 P18090

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Adrenergic, beta-1-, Receptor Proteins (ADRB1) by Origin

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More Proteins for Adrenergic, beta-1-, Receptor Interaction Partners

Zebrafish Adrenergic, beta-1-, Receptor (ADRB1) interaction partners

  1. Zebrafish larvae lacking beta1AR expression by morpholino knockdown displayed lower heart rates than control fish, whereas larvae deficient in both beta2aAR and beta2bAR expression exhibited significantly higher heart rates than controls.

Mouse (Murine) Adrenergic, beta-1-, Receptor (ADRB1) interaction partners

  1. knocking out of the beta1/2 (show TFAP2B Proteins) receptor significantly diminished the ST25 acupuncture-induced inhibition of gastric motility and jejunal motility without significantly altering the enhancement of colonic motility induced by acupuncture at ST25.

  2. Our findings that BAG3 (show BAG3 Proteins) is localized at the sarcolemma and t-tubules while modulating myocyte contraction and action potential duration through specific interaction with the beta1-adrenergic receptor and L-type Ca(2 (show CA2 Proteins)+) channel provide novel insight into the role of BAG3 (show BAG3 Proteins) in cardiomyopathies and increased arrhythmia risks in heart failure.

  3. Galphai2 (show GNAI2 Proteins) deficiency combined with cardiac beta1-adrenoceptor overexpression strongly impaired survival and cardiac function, leading to dilated cardiomyopathy.

  4. Knockout of the C5aR1 (show C5AR1 Proteins) attenuated the effect of beta1-AR in the heart, suggesting an association between the beta1-AR and C5aR1 (show C5AR1 Proteins), although further investigation is required to determine if this is a direct or causal association

  5. Partial gap junction uncoupling increased propensity and amplitude of Ca(2 (show CA2 Proteins)+) alternans, and made them more sensitive to reversal by beta-AR activation, as in isolated myocytes.

  6. These data reveal a novel interplay between the E2F pathway, beta2-adrenergic/PKA/PDE4D, and ERK/c-Src axis in fine tuning the pathological hypertrophic growth response.

  7. Myocardial adrenergic receptor beta 1 preferentially associates with AC5 (show ADCY5 Proteins).

  8. role of beta-ARs (show SLURP1 Proteins) in early muscle regeneration

  9. Phosphorylation of beta1-AR by PKA stimulates active Ca(2 (show CA2 Proteins)+)influx through TRPV5 (show TRPV5 Proteins).

  10. This study report that both beta1- and beta2-ARs (show SLURP1 Proteins) are expressed in a majority of GABAergic interneurons in the medial prefrontal cortex of mice.

Cow (Bovine) Adrenergic, beta-1-, Receptor (ADRB1) interaction partners

Human Adrenergic, beta-1-, Receptor (ADRB1) interaction partners

  1. Analyzing the functional relevance of individual sites using phosphosite-deficient receptor mutants we found phosphorylation of the ADRB1 at Ser461/Ser462 in the distal part of the C-terminus to determine beta-arrestin2 (show ARRB2 Proteins) recruitment and receptor internalization

  2. Studied frequency of ADRB1 Arginine389Glycine (Arg389Gly) and Cytochrome p450 2D6 (show CYP2D6 Proteins)*10 (Cyp2D6 (show CYP2D6 Proteins)*10) polymorphism in cases of heart failure-reduced ejection fraction (HFREF), and to evaluate the influence of the polymorphisms in response to beta-blocker (BB) therapy; found a statistically significant association was observed with CC genotype and Glisin-Glisin (GG) genotype.

  3. Among individuals with previous small artery ischemic stroke, the ADRB1 Gly49 polymorphism was associated with major adverse cardiovascular events, particularly small artery ischemic stroke, a risk that may be increased among beta-blocker-treated individuals.

  4. ADRB1 SNPs were associated with myocardial infarction susceptibility, blood pressure and plasma lipids.

  5. the beta adrenoreceptor Gly 49 allele of the beta1 -adrenergic receptor Ser (show SIGLEC1 Proteins)(49) Gly polymorphisms may increase the risk of implantable cardioverter-defibrillators shock in patients with heart failure, independent of beta-blocker dosage

  6. This study demonstrates that the polypeptide GalNAc-transferase 2 (GalNAc-T2 (show GALNT2 Proteins)) specifically O-glycosylates beta 1-adrenergic receptor at five residues in the extracellular N terminus, including the Ser (show SIGLEC1 Proteins)-49 residue at the location of the common S49G single-nucleotide polymorphism.

  7. The minor alleles of ADRB1 and ADRB3 (show ADRB3 Proteins) were significantly underrepresented in kinesiology students compared with nonmajors.

  8. The ADRB1 Gly389X genotype showed greater response to bisoprolol than the Arg389Arg genotype, suggesting the potential of individually tailoring beta-blocker therapy according to genotype in Korean heart failure patients.

  9. The multiplex SNaPshot method allows for specific and accurate detection of CYP2D6 (show CYP2D6 Proteins) genotypes and ADRB1 genotypes and haplotypes. This platform is simple and efficient and suited for high throughput.

  10. Suggest a common regulatory pattern for the beta(1)-AR/GRK5 (show GRK5 Proteins) which is independent of cellular type or pathology.

Pig (Porcine) Adrenergic, beta-1-, Receptor (ADRB1) interaction partners

Adrenergic, beta-1-, Receptor (ADRB1) Protein Profile

Protein Summary

The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure.

Alternative names and synonyms associated with Adrenergic, beta-1-, Receptor (ADRB1)

  • adrenergic, beta, receptor kinase 1 (ADRBK1)
  • beta-4C adrenergic receptor-like (LOC430991)
  • adrenoceptor beta 1 (ADRB1)
  • adrenergic receptor, beta 1 (adrb1)
  • adrenergic, beta, receptor kinase 1 (LOC100227701)
  • adrenergic receptor, beta 1 (Adrb1)
  • adrenergic, beta-1-, receptor (ADRB1)
  • adrenoceptor beta 1 (Adrb1)
  • adrenoceptor beta 1 (adrb1)
  • Adrb-1 protein
  • ADRB1 protein
  • ADRB1R protein
  • ADRB3 protein
  • ADRBK1 protein
  • B1AR protein
  • BAR1 protein
  • beta-AR protein
  • BETA1AR protein
  • RATB1AR protein
  • RHR protein
  • X-Beta1AR protein
  • zgc:194728 protein
  • zgc:194731 protein

Protein level used designations for ADRB1

beta-adrenergic receptor kinase 1 , adrenergic, beta-1-, receptor , adrenoceptor beta 1 , adrenoceptor beta 3 , beta adrenergic receptor kinase 1 , beta-1-adrenergic receptor , beta-1 adrenergic receptor , tripartite motif-containing 75 , adrenergic, beta, receptor kinase 1 , beta-adrenergic receptor kinase 1-like , beta1-adrenergic G-protein-coupled receptor , beta 1-AR , beta-1 adrenoceptor , beta-1 adrenoreceptor , cardiac beta adrenergic receptor , beta 1 adrenergic receptor , adrenergic receptor, beta 1 , beta 1-adrenergic receptor beta 1-AR , beta 1 adrenergic protein , Beta-1 adrenergic receptor , G-protein-coupled hormone receptor , beta 1-adrenergic receptor

426000 Gallus gallus
430991 Gallus gallus
451363 Pan troglodytes
466206 Pan troglodytes
557194 Danio rerio
721754 Macaca mulatta
100227701 Taeniopygia guttata
100379595 Cavia porcellus
100461893 Pongo abelii
483701 Canis lupus familiaris
100189602 Meleagris gallopavo
11554 Mus musculus
281604 Bos taurus
153 Homo sapiens
24925 Rattus norvegicus
493972 Canis lupus familiaris
397355 Sus scrofa
493971 Felis catus
443528 Ovis aries
399337 Xenopus laevis
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