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Browse our CCR2 (CCR2) ELISA Kits

Full name:
Chemokine (C-C Motif) Receptor 2 ELISA Kits (CCR2)
On www.antibodies-online.com are 14 Chemokine (C-C Motif) Receptor 2 (CCR2) ELISA Kits from 8 different suppliers available. Additionally we are shipping CCR2 Antibodies (296) and CCR2 Proteins (5) and many more products for this protein. A total of 324 CCR2 products are currently listed.
Synonyms:
Cc-ckr-2, CCR-2, Ccr2a, Ccr2b, CD192, Ckr2, Ckr2a, Ckr2b, Cmkbr2, MCP-1-R, mJe-r

CCR2 (CCR2) ELISA Kits by Reactivity

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More ELISA Kits for CCR2 Interaction Partners

Human Chemokine (C-C Motif) Receptor 2 (CCR2) interaction partners

  1. PCSK9 regulates monocyte CCR2 expression and chemotaxis.

  2. CCR2-targeted therapy with PF-04136309 in combination with FOLFIRINOX is safe and tolerable

  3. Binding of J113863 to CCR2 or CCR5 (show CCR5 ELISA Kits) also induced the recruitment of beta-arrestin 2 (show ARRB2 ELISA Kits), whereas UCB35625 did not. UCB35625 induced the chemotaxis of L1.2 cells expressing CCR2 or CCR5 (show CCR5 ELISA Kits). In contrast, J113863 induced the migration of L1.2-CCR2 cells but antagonized the chemokine (show CCL1 ELISA Kits)-induced migration of L1.2-CCR5 (show CCR5 ELISA Kits) cells.

  4. CCL2 (show CCL2 ELISA Kits) suppressed HDL (show HSD11B1 ELISA Kits) internalization and cholesterol efflux via CCR2 induction and p42 (show EPB42 ELISA Kits)/44 MAPK (show MAPK1 ELISA Kits) activation in ECs. CCL2 (show CCL2 ELISA Kits) induction may contribute to impair HDL (show HSD11B1 ELISA Kits) function and form atherosclerosis in coronary artery disease.

  5. High levels of TRAIL-R3 and CCR-2 expression in tumor epithelial cells identified patients with early breast cancer with poor outcomes.

  6. X ray crystal structure of CC chemokine receptor 2 (show CCRL2 ELISA Kits) with orthosteric and allosteric antagonists

  7. Ingestion of an amino acid supplement immediately post-exercise appears to help maintain plasma MCP-1 concentrations and augment CCR2 expression in resistance trained men.

  8. HUMSCs expressing ISZ-sTRAIL might be an efficient therapeutic approach against lung cancer and MCP-1/CCR2 axis is essential for the tumor tropism of HUMSCs

  9. The authors demonstrate a positive correlation between CCR2 receptor gene polymorphism and a subgroup of breast cancer showing poor prognosis, which deserves further investigation in larger samples for validation.

  10. Results of this study indicated that the CCL2-CCR2 axis was involved in the pathogenesis of oral lichen planus and was positively correlated with disease activity.

Mouse (Murine) Chemokine (C-C Motif) Receptor 2 (CCR2) interaction partners

  1. Kupffer cells secrete CCL2 to promote CCR2-expressing neutrophil recruitment from the bone marrow and subsequent infiltration into the liver during ischemia/reperfusion injury. These findings reveal a novel pro-inflammatory role of cell-mediated CCL2-CCR2 interactions during this sterile insult.

  2. CCR2 is dispensable for at least some forms of lung fibrosis and suggest that anti-CCR2 therapies may be ineffective in IL-17 (show IL17A ELISA Kits)-mediated fibrotic disease.

  3. this study shows that that CCR2 signaling is required for monocyte recruitment during Clostridium difficile colitis

  4. this study shows that CCR2-deficient mice display enhanced resistance to Japanese encephalitis virus

  5. this study shows that CCR-2 signaling is involved in the killing of Staphylococcus aureus by murine bone marrow cells

  6. The results indicate that CCR2 plays an essential role in Helicobacter pylori-induced immune tolerance and shed light on a novel mechanism of CCR2-dependent dendritic cell Treg cell induction, which appears to be important in maintaining mucosal homeostasis during Helicobacter pylori infection.

  7. CCR2(-/-) resident cardiac Macrophage favor a more antiinflammatory phenotype relative to WT controls

  8. Endothelial VCAM-1 targeted delivery of the CCR2 antagonist resulted in inhibition of pulmonary metastases both in a murine (MC-38GFP cells) and a human xenograft (patient-derived cells) model.

  9. To interrogate the role of CCR2 activation on Nf1 (show NF1 ELISA Kits)(+/-) neointima formation, authors induced neointima formation by carotid artery ligation in Nf1 (show NF1 ELISA Kits)(+/-) and WT mice with genetic deletion of either MCP1 (show CCL2 ELISA Kits) or CCR2. Loss of MCP-1 (show CPT1B ELISA Kits) or CCR2 expression effectively inhibited Nf1 (show NF1 ELISA Kits)(+/-) neointima formation and reduced macrophage content in the arterial wall.

  10. involved in Staphylococcus aureus-induced MCP-1 (show CPT1B ELISA Kits) production via NF-kB or p38-MAPK (show MAPK14 ELISA Kits) signaling

CCR2 Antigen Profile

Antigen Summary

This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene.

Alternative names and synonyms associated with CCR2

  • chemokine (C-C motif) receptor 2 (CCR2) Elisa Kit
  • chemokine (C-C motif) receptor 2 (Ccr2) Elisa Kit
  • Cc-ckr-2 Elisa Kit
  • CCR-2 Elisa Kit
  • Ccr2a Elisa Kit
  • Ccr2b Elisa Kit
  • CD192 Elisa Kit
  • Ckr2 Elisa Kit
  • Ckr2a Elisa Kit
  • Ckr2b Elisa Kit
  • Cmkbr2 Elisa Kit
  • MCP-1-R Elisa Kit
  • mJe-r Elisa Kit

Protein level used designations for CCR2

C-C chemokine receptor type 2 , MCP-1 receptor , monocyte chemoattractant protein 1 receptor , monocyte chemotactic protein 1 receptor , C-C CHEMOKINE RECEPTOR TYPE 2 (C-C CKR-2) (CC-CKR-2) (CCR-2) (CCR2) (JE/FIC RECEPTOR) (MCP-1 RECEPTOR) , C-C CKR-2 , CCR-2 , JE/FIC receptor , MIP-1 alphaR , chemoattractant protein-1 receptor , chemokine (C-C) receptor 2 , CC-CKR-2 , chemokine receptor CCR2 , MCP-1-R , chemokine receptor

GENE ID SPECIES
729230 Homo sapiens
12772 Mus musculus
60463 Rattus norvegicus
484790 Canis lupus familiaris
574098 Macaca mulatta
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