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Full name:
Chemokine (C-C Motif) Receptor 2 ELISA Kits (CCR2)
On www.antibodies-online.com are 14 Chemokine (C-C Motif) Receptor 2 (CCR2) ELISA Kits from 8 different suppliers available. Additionally we are shipping CCR2 Antibodies (298) and CCR2 Proteins (5) and many more products for this protein. A total of 326 CCR2 products are currently listed.
Synonyms:
Cc-ckr-2, CCR-2, Ccr2a, Ccr2b, CD192, Ckr2, Ckr2a, Ckr2b, Cmkbr2, MCP-1-R, mJe-r

CCR2 (CCR2) ELISA Kits by Reactivity

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Human Chemokine (C-C Motif) Receptor 2 (CCR2) interaction partners

  1. The findings of the work indicate a role for Galphaq (show GNAQ ELISA Kits) and/or Galpha14 and in CCR2a/CCR2b-stimulated Rho A (show RHOA ELISA Kits) GTPase (show RACGAP1 ELISA Kits)-mediated serum response factor activation.

  2. Endogenous TRAIL/TRAIL-R-mediated CCL2 (show CCL2 ELISA Kits) secretion promotes accumulation of tumor-supportive immune cells in the cancer microenvironment.

  3. CCL2 (show CCL2 ELISA Kits)/CCR2 axis is expressed in the majority of monocytoid Acute myeloid leukemia (show BCL11A ELISA Kits) blasts

  4. CCR2B and beta2AR (show ADRB2 ELISA Kits) signals to FLNa (show FLNA ELISA Kits) to stimulate its endocytosis and recycling to the plasma membrane.

  5. this study shows that CYTL1 possesses chemotactic activity and demonstrates that its functional receptor is CCR2B

  6. PCSK9 regulates monocyte CCR2 expression and chemotaxis.

  7. CCR2-targeted therapy with PF-04136309 in combination with FOLFIRINOX is safe and tolerable

  8. Binding of J113863 to CCR2 or CCR5 (show CCR5 ELISA Kits) also induced the recruitment of beta-arrestin 2 (show ARRB2 ELISA Kits), whereas UCB35625 did not. UCB35625 induced the chemotaxis of L1.2 cells expressing CCR2 or CCR5 (show CCR5 ELISA Kits). In contrast, J113863 induced the migration of L1.2-CCR2 cells but antagonized the chemokine (show CCL1 ELISA Kits)-induced migration of L1.2-CCR5 (show CCR5 ELISA Kits) cells.

  9. CCL2 (show CCL2 ELISA Kits) suppressed HDL (show HSD11B1 ELISA Kits) internalization and cholesterol efflux via CCR2 induction and p42 (show EPB42 ELISA Kits)/44 MAPK (show MAPK1 ELISA Kits) activation in ECs. CCL2 (show CCL2 ELISA Kits) induction may contribute to impair HDL (show HSD11B1 ELISA Kits) function and form atherosclerosis in coronary artery disease.

  10. High levels of TRAIL-R3 and CCR-2 expression in tumor epithelial cells identified patients with early breast cancer with poor outcomes.

Mouse (Murine) Chemokine (C-C Motif) Receptor 2 (CCR2) interaction partners

  1. CCR2 expression on bone marrow-derived cells, likely macrophages, is essential to muscle regeneration independent of TLR signaling, aging, and sex.

  2. we demonstrated that CX3CR1 (show CX3CR1 ELISA Kits)(Lo)CCR2(Hi) monocytes were recruited to the GBM, where they transitioned to CX3CR1 (show CX3CR1 ELISA Kits)(Hi)CCR2(Lo) macrophages and CX3CR1 (show CX3CR1 ELISA Kits)(Hi)CCR2(-) microglia-like cells. Infiltrating macrophages/monocytes constituted approximately 85% of the total TAM (show CCNA1 ELISA Kits) population, with resident microglia accounting for the approximately 15% remaining.

  3. we characterized a novel regulatory network in macrophages, in which CCR2 activates PI3K-AKT (show AKT1 ELISA Kits)-mTOR (show FRAP1 ELISA Kits) signaling to mediate HIF-1alpha (show HIF1A ELISA Kits) expression, which then drives VEGF-C (show VEGFC ELISA Kits) expression to promote lymphangiogenesis.

  4. CXCR4 (show CXCR4 ELISA Kits), CCR2, and CX3CR1 (show CX3CR1 ELISA Kits) direct dendritic cell precursors from the bone marrow to the lung differentially.

  5. The findings suggest that CCR2 deficiency does not provide a sustained benefit and that Ly6C(low) macrophages may contribute to the progressive fibrosis and dysfunction of mdx (show DMD ELISA Kits)(5cv) diaphragm.

  6. In Ccr2(-/-) mice, a damaged microglia recruitment was shown in retina and this could protect the visual function in electroretinogram and alleviate the photoreceptor apoptosis.

  7. This study establishes ECL1i as the first allosteric inhibitor of CCR2 with functional selectivity.

  8. the individual and combined actions of CCL2 (show CCL2 ELISA Kits)/CCR2 and CX3CL1 (show CX3CL1 ELISA Kits)/CX3CR1 (show CX3CR1 ELISA Kits) in hypoxia-induced pulmonary hypertension in mice, is reported.

  9. Gas6 (show GAS6 ELISA Kits) specifically promotes the recruitment of inflammatory CCR2(hi)CX3CR1 (show CX3CR1 ELISA Kits)(lo) monocytes through the regulation of both CCR2 and CCL2 (show CCL2 ELISA Kits) during deep venous thrombosis.

  10. macrophage-specific chemokine (C-C Motif) receptor 2 (Ccr2) knockout (M-Ccr2KO) and intestinal epithelial cell-specific tamoxifen-inducible Ccl2 (show CCL2 ELISA Kits) knockout (Vil (show VIL1 ELISA Kits)-Ccl2KO) mice, were studied.

CCR2 Antigen Profile

Antigen Summary

This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene.

Alternative names and synonyms associated with CCR2

  • chemokine (C-C motif) receptor 2 (CCR2) Elisa Kit
  • chemokine (C-C motif) receptor 2 (Ccr2) Elisa Kit
  • Cc-ckr-2 Elisa Kit
  • CCR-2 Elisa Kit
  • Ccr2a Elisa Kit
  • Ccr2b Elisa Kit
  • CD192 Elisa Kit
  • Ckr2 Elisa Kit
  • Ckr2a Elisa Kit
  • Ckr2b Elisa Kit
  • Cmkbr2 Elisa Kit
  • MCP-1-R Elisa Kit
  • mJe-r Elisa Kit

Protein level used designations for CCR2

C-C chemokine receptor type 2 , MCP-1 receptor , monocyte chemoattractant protein 1 receptor , monocyte chemotactic protein 1 receptor , C-C CHEMOKINE RECEPTOR TYPE 2 (C-C CKR-2) (CC-CKR-2) (CCR-2) (CCR2) (JE/FIC RECEPTOR) (MCP-1 RECEPTOR) , C-C CKR-2 , CCR-2 , JE/FIC receptor , MIP-1 alphaR , chemoattractant protein-1 receptor , chemokine (C-C) receptor 2 , CC-CKR-2 , chemokine receptor CCR2 , MCP-1-R , chemokine receptor

GENE ID SPECIES
729230 Homo sapiens
12772 Mus musculus
60463 Rattus norvegicus
484790 Canis lupus familiaris
574098 Macaca mulatta
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