Browse our CCR6 Proteins (CCR6)

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Chemokine (C-C Motif) Receptor 6 Proteins (CCR6)
On are 4 Chemokine (C-C Motif) Receptor 6 (CCR6) Proteins from 3 different suppliers available. Additionally we are shipping CCR6 Antibodies (282) and CCR6 Kits (20) and many more products for this protein. A total of 312 CCR6 products are currently listed.
BN-1, C-C CKR-6, CC-CKR-6, CCR-6, CD196, CKR-L3, CKRL3, Cmkbr6, DCR2, DRY6, GPR29, GPRCY4, KY411, STRL22
list all proteins Gene Name GeneID UniProt
CCR6 1235 P51684
Rat CCR6 CCR6 308163  
CCR6 12458 O54689

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CCR6 Proteins (CCR6) by Origin

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More Proteins for CCR6 Interaction Partners

Human Chemokine (C-C Motif) Receptor 6 (CCR6) interaction partners

  1. The percentage of CXCR3 (show CXCR3 Proteins)(+) CD4 (show CD4 Proteins)(+) TEM (show CYLD Proteins) cells negatively correlated with the severity of the cutaneous disease in psoriasis patients. Importantly CLA (show SELPLG Proteins)(+) CD4 (show CD4 Proteins)(+) TCM cells expressing CCR6(+) or CCR4 (show CCR4 Proteins)(+)CXCR3 (show CXCR3 Proteins)(+) negatively correlated with psoriasis severity suggesting recruitment to the skin compartment.

  2. High CCR6 expression is associated with B-lymphoblastic lymphoma with inflammation.

  3. CCR6 expression was higher in cells derived from node-positive cases and highest expression was in cells derived from metastatic cases of colon cancer.

  4. The study suggests that a genetic interaction between DPP4 (show DPP4 Proteins) and CCR6 is involved in RA susceptibility

  5. point mutations in CCR6 can result in either a gain or loss of receptor function

  6. Rheumatoid arthritis-associated double nucleotide polymorphism in CCR6 regulates CCR6 via PARP-1 (show PARP1 Proteins).

  7. This study evaluated the role of CCL20 (show CCL20 Proteins) and CCR6 in the regulation of laryngeal neoplasms; it showed that these proteins acted on proliferation and metastasis via the p38 (show CRK Proteins) pathway and multiple microRNAs.

  8. CCR6 expression may be a novel biomarker for predicting clinical outcomes for gastric cancer patients.

  9. Cell migration assays showed that TNF-alpha (show TNF Proteins) treatment significantly increased the rate of migrated cells in those cells in which it also increased the membrane expression of CCR6 (TPC-1 (show TPCN1 Proteins) and BCPAP) as compared to basal condition

  10. There were early increased plasma concentrations of CCL20 (show CCL20 Proteins) and CCR6 in patients with sepsis. CCL20 (show CCL20 Proteins) and CCR6 correlate with severity of illness in ICU patients. Levels of CCR6 predicted the length of patients' admission.

Mouse (Murine) Chemokine (C-C Motif) Receptor 6 (CCR6) interaction partners

  1. CCR6 deficiency affects hepatic inflammatory cell recruitment resulting in the promotion of hepatic inflammation and fibrosis.

  2. in mice, activated B cells use the chemokine receptor (show CCR1 Proteins) CCR6 to access the subepithelial dome (SED) of Peyer's patches.

  3. CCR6 might be crucial for optimal development of Th2 immune responses.

  4. This study delineated for the first time a role for CCR6 in the development of breast cancer.

  5. results suggest a key role for CD28 (show CD28 Proteins) costimulation in promoting a central Treg to eTreg transition with appropriate upregulation of chemokine (show CCL1 Proteins) receptors such as CCR6 that are required for tissue homing

  6. CCR6-dependent positioning of memory B cells is essential for their ability to mount a recall response to antigen.

  7. these data indicate that CCR6 has a supplementary role in coordination of early thymocyte precursor migration events important for normal subsequent thymocyte precursor development, but is not required for normal nTreg development.

  8. CCR6 deficieny leads to a diminished cerebral immune response in experimental pneumococcal meningitis.

  9. The results of this study suggest that ccr6 may play a role in cognition and learning behaviour, as well as anxiety and other behaviours.

  10. Chemokine (show CCL1 Proteins) receptors CCR6 and CXCR3 (show CXCR3 Proteins) are necessary for CD4 (show CD4 Proteins)(+) T cell mediated ocular surface disease in experimental dry eye disease.

CCR6 Protein Profile

Protein Summary

This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene.

Alternative names and synonyms associated with CCR6

  • chemokine (C-C motif) receptor 6 (LOC100229899)
  • chemokine (C-C motif) receptor 6 (CCR6)
  • chemokine (C-C motif) receptor 6 (Ccr6)
  • BN-1 protein
  • C-C CKR-6 protein
  • CC-CKR-6 protein
  • CCR-6 protein
  • CD196 protein
  • CKR-L3 protein
  • CKRL3 protein
  • Cmkbr6 protein
  • DCR2 protein
  • DRY6 protein
  • GPR29 protein
  • GPRCY4 protein
  • KY411 protein
  • STRL22 protein

Protein level used designations for CCR6

chemokine (C-C motif) receptor 6 , C-C chemokine receptor type 6 , CC chemokine receptor 6 , c-C chemokine receptor type 6-like , G protein-coupled receptor 29 , G-protein coupled receptor 29 , LARC receptor , chemokine (C-C) receptor 6 , chemokine receptor-like 3 , seven-transmembrane receptor, lymphocyte, 22

100229899 Taeniopygia guttata
519716 Bos taurus
574335 Macaca mulatta
769278 Gallus gallus
100452216 Pongo abelii
100612069 Pan troglodytes
1235 Homo sapiens
308163 Rattus norvegicus
12458 Mus musculus
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