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CCR6 Products

(Chemokine (C-C Motif) Receptor 6 (CCR6))

Categories

This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008].

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Featured CCR6 Categories

CCR6 Antibodies

High quality antibodies with extensive validation data.

CCR6 ELISA Kits

Reliable ELISA kits for a wide range of species.

CCR6 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CCR6 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, FACS
Validations
  • (5)
Cat. No. ABIN7193565
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA
Validations
  • (1)
  • (3)
Cat. No. ABIN731093
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p)
Validations
  • (1)
  • (2)
Cat. No. ABIN540551
Quantity 100 μg
Datasheet Datasheet

Recommended CCR6 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965714
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965713
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6954651
Quantity 96 tests
Datasheet Datasheet

Recommended CCR6 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3098500
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3131727
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN7092813
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our CCR6 products

Bath, Ding, Wilson, Verhoven, Boldt, Sukhwal, Reese, Panzer, Djamali, Redfield: "Desensitization and treatment with APRIL/BLyS blockade in rodent kidney transplant model." in: PLoS ONE, Vol. 14, Issue 2, pp. e0211865, (2019) (PubMed).

Zhang, Xia, Li, He, Li, Guo, Wu, Feng: "CD44 Assists the Topical Anti-Psoriatic Efficacy of Curcumin-Loaded Hyaluronan-Modified Ethosomes: A New Strategy for Clustering Drug in Inflammatory Skin." in: Theranostics, Vol. 9, Issue 1, pp. 48-64, (2019) (PubMed).

Chen, Martindale, Cramer, Gorospe, Atasoy, Drew, Yu: "The RNA-binding protein HuR contributes to neuroinflammation by promoting C-C chemokine receptor 6 (CCR6) expression on Th17 cells." in: The Journal of biological chemistry, Vol. 292, Issue 35, pp. 14532-14543, (2017) (PubMed).

Dorgham, Dejou, Piesse, Gorochov, Pène, Yssel: "Identification of the Single Immunodominant Region of the Native Human CC Chemokine Receptor 6 Recognized by Mouse Monoclonal Antibodies." in: PLoS ONE, Vol. 11, Issue 6, pp. e0157740, (2017) (PubMed).

Ho, Bongartz, Liu, Kalari, Goss, Shepherd, Goetz, Kubo, Ingle, Wang, Weinshilboum: "Estrogen, SNP-Dependent Chemokine Expression and Selective Estrogen Receptor Modulator Regulation." in: Molecular endocrinology (Baltimore, Md.), Vol. 30, Issue 3, pp. 382-98, (2016) (PubMed).

Stojić-Vukanić, Pilipović, Vujnović, Nacka-Aleksić, Petrović, Arsenović-Ranin, Dimitrijević, Leposavić: "GM-CSF-Producing Th Cells in Rats Sensitive and Resistant to Experimental Autoimmune Encephalomyelitis." in: PLoS ONE, Vol. 11, Issue 11, pp. e0166498, (2016) (PubMed).

Kapur, Mir, Clark Iii, Krishnamurti, Beech, Lillard, Singh: "CCR6 expression in colon cancer is associated with advanced disease and supports epithelial-to-mesenchymal transition." in: British journal of cancer, Vol. 114, Issue 12, pp. 1343-51, (2016) (PubMed).

Cecchinato, Bernasconi, Speck, Proietti, Sauermann, DAgostino, Danelon, Rezzonico Jost, Grassi, Raeli, Schöni-Affolter, Stahl-Hennig, Uguccioni: "Impairment of CCR6+ and CXCR3+ Th Cell Migration in HIV-1 Infection Is Rescued by Modulating Actin Polymerization." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 198, Issue 1, pp. 184-195, (2016) (PubMed).

Kalyanasundaram Bhanumathy, Zhang, Xie, Xu, Tan, Xiang: "Potent immunotherapy against well-established thymoma using adoptively transferred transgene IL-6-engineered dendritic cell-stimulated CD8(+) T-cells with prolonged survival and enhanced cytotoxicity." in: The journal of gene medicine, (2015) (PubMed).

Funakoshi, Shimizu, Numata, Ato, Melchers, Ohnishi: "BILL-cadherin/cadherin-17 contributes to the survival of memory B cells." in: PLoS ONE, Vol. 10, Issue 1, pp. e0117566, (2015) (PubMed).

Synonyms and alternative names related to CCR6

C-C motif chemokine receptor 6 (CCR6), C-C motif chemokine receptor 6 (Ccr6), chemokine (C-C motif) receptor 6 (Ccr6), BN-1, C-C CKR-6, CC-CKR-6, CCR-6, CD196, CKR-L3, CKRL3, CMKBR6, Cmkbr6, DCR2, DRY6, GPR29, GPRCY4, KY411, STRL22

Protein level used designations for CCR6

  • chemokine (C-C motif) receptor 6
  • C-C chemokine receptor type 6
  • CC chemokine receptor 6
  • c-C chemokine receptor type 6-like
  • G protein-coupled receptor 29
  • G-protein coupled receptor 29
  • LARC receptor
  • chemokine (C-C) receptor 6
  • chemokine receptor-like 3
  • seven-transmembrane receptor, lymphocyte, 22
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