Browse our LGALS1 Proteins (LGALS1)

Full name:
Lectin, Galactoside-Binding, Soluble, 1 Proteins (LGALS1)
On www.antibodies-online.com are 53 Lectin, Galactoside-Binding, Soluble, 1 (LGALS1) Proteins from 18 different suppliers available. Additionally we are shipping LGALS1 Antibodies (267) and LGALS1 Kits (69) and many more products for this protein. A total of 404 LGALS1 products are currently listed.
Synonyms:
AA410090, Gal-1, GAL1, Galaptin, Galbp, galectin-1, GB10026, GBP, L-14.5, L14, Lect14, LGALS1, LGAS1, MGC64502
list all proteins Gene Name GeneID UniProt
LGALS1 16852 P16045
LGALS1 3956 P09382
LGALS1 56646 P11762

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LGALS1 Proteins (LGALS1) by Origin

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Top referenced LGALS1 Proteins

  1. Human LGALS1 Protein expressed in CHO Cells - ABIN2666816 : Almkvist, Karlsson: Galectins as inflammatory mediators. in Glycoconjugate journal 2004 (PubMed)
    Show all 7 references for 2666816

  2. Human LGALS1 Protein expressed in Escherichia coli (E. coli) - ABIN2002512 : Nishi, Abe, Iwaki, Yoshida, Itoh, Shoji, Kamitori, Hirabayashi, Nakamura: Functional and structural bases of a cysteine-less mutant as a long-lasting substitute for galectin-1. in Glycobiology 2008 (PubMed)
    Show all 4 references for 2002512

  3. Mouse (Murine) LGALS1 Protein expressed in Escherichia coli (E. coli) - ABIN2007320 : He, Baum: Presentation of galectin-1 by extracellular matrix triggers T cell death. in The Journal of biological chemistry 2004 (PubMed)
    Show all 3 references for 2007320

  4. Mouse (Murine) LGALS1 Protein expressed in Escherichia coli (E. coli) - ABIN1098218 : Ilarregui, Croci, Bianco, Toscano, Salatino, Vermeulen, Geffner, Rabinovich: Tolerogenic signals delivered by dendritic cells to T cells through a galectin-1-driven immunoregulatory circuit involving interleukin 27 and interleukin 10. in Nature immunology 2009 (PubMed)
    Show all 2 references for 1098218

More Proteins for LGALS1 Interaction Partners

Mouse (Murine) Lectin, Galactoside-Binding, Soluble, 1 (LGALS1) interaction partners

  1. Gal-1 functions as an important regulator in RNV and offers a promising strategy for the treatment of RNV diseases, such as proliferative diabetic retinopathy and retinopathy of prematurity.

  2. These findings demonstrate that galectin-1 is required for i.v. tolerance induction, likely via induction of tolerogenic DCs leading to enhanced development of Tr1 cells, Treg cells, and downregulation of proinflammatory responses.

  3. this study shows that galectin-1 secreted by Sertoli cells plays a pivotal role in the differentiation of functionally tolerogenic dendritic cells

  4. analysis of the effect of low-temperature plasma on the expression of galectin-1, -2, and -3 in the healing skin compared with those of electrocoagulation conducted with a high-frequency electrical coagulator

  5. Tumor-driven, unremitting expression of Satb1 (show SATB1 Proteins) in activated Zbtb46 (show ZNF340 Proteins)+ inflammatory dendritic cells that infiltrate ovarian tumors results in an immunosuppressive phenotype characterized by increased secretion of tumor-promoting Galectin-1 and IL-6 (show IL6 Proteins).

  6. Gal-1 does not play a role in the systemic immunosuppressive effect of Mesenchymal stem cells.

  7. Galectin-1 has a role in driving lymphoma CD20 (show MS4A1 Proteins) immunotherapy resistance in a mouse model

  8. These findings highlight the importance of the inflammatory micro-environment of mucosal tissues in modulating intestinal epithelial cells susceptibility to the immunoregulatory lectin Gal-1 and its role in epithelial cell homeostasis.

  9. results unveil a dual role of endogenous versus exogenous Gal-1 in the control of autoimmune testis inflammation.

  10. GAL-1 is valuable biomarker of surgical stress after cardiac surgery.

Human Lectin, Galactoside-Binding, Soluble, 1 (LGALS1) interaction partners

  1. Galectin-1-driven production of SDF-1 (show CXCL12 Proteins) in pancreatic stellate cells through activation of NF-kappaB (show NFKB1 Proteins) promotes metastasis in pancreatic ductal adenocarcinoma.

  2. Gal-1 expression by MM cells was upregulated in hypoxic conditions and stable knockdown of hypoxia inducible factor-1alpha significantly downregulated its expression

  3. Gal1 may be a useful marker for determining whether morphologic changes in oral cells are reactive or neoplastic

  4. The aim of this study was to analyze the syncytium formation abilities of BeWo cells that were gal-1 silenced.

  5. Studies provide evidence that galectin-1 belongs to the group of potential pathogenic molecules in systemic lupus erythematosus. [review]

  6. an intact dimer interface of Gal-1 is required for it to positively regulate H-rasG12V nanoclustering, but negatively K-rasG12V nanoclustering.

  7. Our results suggest that Gal-1 and ASPP2 functionally compete in nanocluster for active Ras on the plasma membrane. ASPP2 dominates the biological outcome, thus switching from a Gal-1 supported growth-promoting setting to a senescence inducing and stemness suppressive program in cancer cells. Our results support Ras nanocluster as major integrators of tumour fate decision events.

  8. Galectin-1 and Galectin-3 (show LGALS3 Proteins) are novel-binding partners for human FVIII (show F8 Proteins). Gal-1 binding can influence the procoagulant activity of FVIII (show F8 Proteins).

  9. Proteomics of the interstitial fluid in subcutaneous adipose tissue in vivo identified a novel adipokine, galectin-1, with a potential role in the pathophysiology of type 2 diabetes.

  10. Suggest that galectin-1 is a protective factor against the development of digital vasculopathy in systemic sclerosis.

Cow (Bovine) Lectin, Galactoside-Binding, Soluble, 1 (LGALS1) interaction partners

  1. Data suggest that galectin-1 and VEGFR-2 (show KDR Proteins) are expressed at mid-luteal stages in luteal cells of corpus luteum; galectin-1 binds directly to asparagine-linked glycans (N-glycans) on VEGFR-2 (show KDR Proteins) in luteal cells.

  2. The relative abundance of PIBF (show PIBF1 Proteins), LGALS1, LGALS3 (show LGALS2 Proteins), LGALS3BP (show LGALS3BP Proteins), and LGALS9 (show LGALS9 Proteins) mRNA would display a differential expression pattern in the endometrium.

  3. The binding affinity and specificity of galectin-1 for eight different beta-galactosyl terminal disaccharides was studied using molecular-dynamics simulations.

Pig (Porcine) Lectin, Galactoside-Binding, Soluble, 1 (LGALS1) interaction partners

  1. Gal-1 may serve as an adhesion molecule (show NCAM1 Proteins) to interact with both cells and laminins

  2. Gal-1 is expressed in a wide range of porcine tissues, including striated (show NSDHL Proteins) muscle, liver, lung, brain, kidney, spleen, and intestine

  3. LGALS1 was found widely expressed in all tissues and transient transfection indicated that galectin-1 locates both in cytoplasm and nucleus.

LGALS1 Protein Profile

Protein Summary

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. This gene product may act as an autocrine negative growth factor that regulates cell proliferation.

Alternative names and synonyms associated with LGALS1

  • galectin-1-like (LOC100069841)
  • lectin, galactoside-binding, soluble, 1 (lgals1)
  • lectin, galactoside-binding, soluble, 1 (LGALS1)
  • galectin 1 (galectin1)
  • galectin-1 (CC1G_05003)
  • galectin-1 (CC1G_05004)
  • galectin-1 (CC1G_05005)
  • galectin-1 (GAL-1)
  • galectin-1-like (LOC100751963)
  • lectin, galactose binding, soluble 1 (Lgals1)
  • lectin, galactoside-binding, soluble, 1 (Lgals1)
  • AA410090 protein
  • Gal-1 protein
  • GAL1 protein
  • Galaptin protein
  • Galbp protein
  • galectin-1 protein
  • GB10026 protein
  • GBP protein
  • L-14.5 protein
  • L14 protein
  • Lect14 protein
  • LGALS1 protein
  • LGAS1 protein
  • MGC64502 protein

Protein level used designations for LGALS1

lectin, galactoside-binding, soluble, 1 , galectin 1 , lectin, galactoside-binding, soluble, 1 (galectin 1) , 14 kDa lectin , 14K beta-galactoside-binding lectin , C-14 , beta-galactoside-binding lectin , galectin CG-1B , gbl , galectin-1 , Beta-galactoside-binding lectin L-14-I , Lactose-binding lectin 1 , Lectin galactoside-binding soluble 1 , S-Lac lectin 1 , beta-galactoside binding protein , beta-galactoside-binding lectin L-14-I , galaptin , lactose-binding lectin 1 , lectin galactoside-binding soluble 1 , 14 kDa laminin-binding protein , HBL , HLBP14 , HPL , beta-galactoside-binding protein 14kDa , gal-1 , putative MAPK-activating protein PM12 , RL 14.5 , lectin, galactose binding, soluble 1

GENE ID SPECIES
100069841 Equus caballus
379433 Xenopus laevis
742148 Pan troglodytes
396491 Gallus gallus
408848 Apis mellifera
6012550 Coprinopsis cinerea okayama7130
6012551 Coprinopsis cinerea okayama7#130
6012552 Coprinopsis cinerea okayama7130
100196938 Papio anubis
443298 Ovis aries
100751963 Cricetulus griseus
16852 Mus musculus
3956 Homo sapiens
326598 Bos taurus
414915 Sus scrofa
56646 Rattus norvegicus
610276 Canis lupus familiaris
100722354 Cavia porcellus
100173289 Pongo abelii
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