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Browse our LGALS1 Proteins (LGALS1)

Full name:
Lectin, Galactoside-Binding, Soluble, 1 Proteins (LGALS1)
On are 52 Lectin, Galactoside-Binding, Soluble, 1 (LGALS1) Proteins from 17 different suppliers available. Additionally we are shipping LGALS1 Antibodies (229) and LGALS1 Kits (65) and many more products for this protein. A total of 359 LGALS1 products are currently listed.
AA410090, Gal-1, GAL1, Galaptin, Galbp, galectin-1, GB10026, GBP, L-14.5, L14, Lect14, LGALS1, LGAS1, MGC64502
list all proteins Gene Name GeneID UniProt
LGALS1 16852 P16045
LGALS1 3956 P09382
LGALS1 56646 P11762

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LGALS1 Proteins (LGALS1) by Origin

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Top referenced LGALS1 Proteins

  1. Human LGALS1 Protein expressed in CHO Cells - ABIN2666816 : Almkvist, Karlsson: Galectins as inflammatory mediators. in Glycoconjugate journal 2004 (PubMed)
    Show all 7 references for ABIN2666816

  2. Human LGALS1 Protein expressed in Escherichia coli (E. coli) - ABIN2002512 : Nishi, Abe, Iwaki, Yoshida, Itoh, Shoji, Kamitori, Hirabayashi, Nakamura: Functional and structural bases of a cysteine-less mutant as a long-lasting substitute for galectin-1. in Glycobiology 2008 (PubMed)
    Show all 4 references for ABIN2002512

  3. Mouse (Murine) LGALS1 Protein expressed in Escherichia coli (E. coli) - ABIN2007320 : He, Baum: Presentation of galectin-1 by extracellular matrix triggers T cell death. in The Journal of biological chemistry 2004 (PubMed)
    Show all 3 references for ABIN2007320

  4. Mouse (Murine) LGALS1 Protein expressed in Escherichia coli (E. coli) - ABIN1098218 : Ilarregui, Croci, Bianco, Toscano, Salatino, Vermeulen, Geffner, Rabinovich: Tolerogenic signals delivered by dendritic cells to T cells through a galectin-1-driven immunoregulatory circuit involving interleukin 27 and interleukin 10. in Nature immunology 2009 (PubMed)
    Show all 2 references for ABIN1098218

More Proteins for LGALS1 Interaction Partners

Mouse (Murine) Lectin, Galactoside-Binding, Soluble, 1 (LGALS1) interaction partners

  1. Tumor-driven, unremitting expression of Satb1 (show SATB1 Proteins) in activated Zbtb46 (show ZNF340 Proteins)+ inflammatory dendritic cells that infiltrate ovarian tumors results in an immunosuppressive phenotype characterized by increased secretion of tumor-promoting Galectin-1 and IL-6 (show IL6 Proteins).

  2. Gal-1 does not play a role in the systemic immunosuppressive effect of Mesenchymal stem cells.

  3. Galectin-1 has a role in driving lymphoma CD20 (show MS4A1 Proteins) immunotherapy resistance in a mouse model

  4. These findings highlight the importance of the inflammatory micro-environment of mucosal tissues in modulating intestinal epithelial cells susceptibility to the immunoregulatory lectin Gal-1 and its role in epithelial cell homeostasis.

  5. results unveil a dual role of endogenous versus exogenous Gal-1 in the control of autoimmune testis inflammation.

  6. GAL-1 is valuable biomarker of surgical stress after cardiac surgery.

  7. The authors found that exposure of HL-1 (show ASGR1 Proteins) cardiac cells to Gal-1 reduced the percentage of infection by two different Trypanosoma cruzi strains, Tulahuen (TcVI) and Brazil (TcI (show LXN Proteins)).

  8. GAL1/pre-B-cell receptor interaction modifies GAL1/glycan affinity and particularly inhibits binding to LacNAc containing epitopes

  9. Data indicate the relevance of the galectin-1 (Gal-1)-glycan axis in sperm function with implications in mammalian reproductive biology.

  10. Galectin-1 accumulates in neurofilamentous lesions in SOD1 (show SOD1 Proteins)(G93A) mice, as previously reported in humans with amyotrophic lateral sclerosis (

Human Lectin, Galactoside-Binding, Soluble, 1 (LGALS1) interaction partners

  1. Differential expression of LGALS1 and/or LGALS3 (show LGALS3 Proteins) in patients with myeloproliferative neoplasm (MPN (show PRSS27 Proteins)) is linked with JAK2 (show JAK2 Proteins) V617F status mutation in these diseases and state of cell differentiation.

  2. Gal-1-regulated carcinoma-associated fibroblast activation promotes breast cancer cell metastasis by upregulating MMP-9 (show MMP9 Proteins) expression.

  3. It is a beta-galactose-binding animal lectin and known to be distributed throughout the body.

  4. Our functional analyses of galectin-1 in urinary bladder urothelial carcinoma provided novel insights into the critical role of galectin-1 in tumor progression and invasion. These results revealed that silencing the galectin-1-mediated MAPK (show MAPK1 Proteins) signaling pathway presented a novel strategy for bladder cancer therapy.

  5. the TLR4 (show TLR4 Proteins)/Gal-1 signaling pathway regulates lactate-mediated EMT (show ITK Proteins) processes through the activation of ADAM10 (show ADAM10 Proteins) and ADAM17 (show ADAM17 Proteins) in colon cancer cells.

  6. These findings suggest that Gal-1 plays an important role in immune escape of gingival squamous cell carcinoma cells, and Gal-1 expression level may be a useful clinicopathological prognostic marker for this cancer.

  7. Galectin-1 gene silencing would improve the sensitivity of A549/DDP (show TIMM8A Proteins) cells to cisplatin in vivo and in vitro.

  8. In this study, gal-1, -2, -3 and -13 were investigated systematically in the trophoblast and decidua compartment of intrauterine growth restriction (IUGR) placentas and normal third trimester control placentas and stratified by fetal gender and gestational age. Gal-1 Expression Shows No Significant Changes in IUGR Placentas in Villous Trophoblasts.

  9. Galectin-1 overexpression activates the FAK (show PTK2 Proteins)/PI3K (show PIK3CA Proteins)/AKT (show AKT1 Proteins) pathway by upregulating expression of alphavbeta3 integrin, leading to enhanced hepatocellular carcinoma invasion via epithelial-mesenchymal transition and sorafenib resistance.

  10. results show that HELLP syndrome is associated with increased circulating levels of gal-1

Cow (Bovine) Lectin, Galactoside-Binding, Soluble, 1 (LGALS1) interaction partners

  1. Data suggest that galectin-1 and VEGFR-2 (show KDR Proteins) are expressed at mid-luteal stages in luteal cells of corpus luteum; galectin-1 binds directly to asparagine-linked glycans (N-glycans) on VEGFR-2 (show KDR Proteins) in luteal cells.

  2. The relative abundance of PIBF (show PIBF1 Proteins), LGALS1, LGALS3 (show LGALS2 Proteins), LGALS3BP (show LGALS3BP Proteins), and LGALS9 (show LGALS9 Proteins) mRNA would display a differential expression pattern in the endometrium.

  3. The binding affinity and specificity of galectin-1 for eight different beta-galactosyl terminal disaccharides was studied using molecular-dynamics simulations.

Pig (Porcine) Lectin, Galactoside-Binding, Soluble, 1 (LGALS1) interaction partners

  1. Gal-1 may serve as an adhesion molecule (show NCAM1 Proteins) to interact with both cells and laminins

  2. Gal-1 is expressed in a wide range of porcine tissues, including striated (show NSDHL Proteins) muscle, liver, lung, brain, kidney, spleen, and intestine

  3. LGALS1 was found widely expressed in all tissues and transient transfection indicated that galectin-1 locates both in cytoplasm and nucleus.

LGALS1 Protein Profile

Protein Summary

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. This gene product may act as an autocrine negative growth factor that regulates cell proliferation.

Alternative names and synonyms associated with LGALS1

  • galectin-1-like (LOC100069841)
  • lectin, galactoside-binding, soluble, 1 (lgals1)
  • lectin, galactoside-binding, soluble, 1 (LGALS1)
  • galectin 1 (galectin1)
  • galectin-1 (CC1G_05003)
  • galectin-1 (CC1G_05004)
  • galectin-1 (CC1G_05005)
  • galectin-1 (GAL-1)
  • galectin-1-like (LOC100751963)
  • lectin, galactose binding, soluble 1 (Lgals1)
  • lectin, galactoside-binding, soluble, 1 (Lgals1)
  • AA410090 protein
  • Gal-1 protein
  • GAL1 protein
  • Galaptin protein
  • Galbp protein
  • galectin-1 protein
  • GB10026 protein
  • GBP protein
  • L-14.5 protein
  • L14 protein
  • Lect14 protein
  • LGALS1 protein
  • LGAS1 protein
  • MGC64502 protein

Protein level used designations for LGALS1

lectin, galactoside-binding, soluble, 1 , galectin 1 , lectin, galactoside-binding, soluble, 1 (galectin 1) , 14 kDa lectin , 14K beta-galactoside-binding lectin , C-14 , beta-galactoside-binding lectin , galectin CG-1B , gbl , galectin-1 , Beta-galactoside-binding lectin L-14-I , Lactose-binding lectin 1 , Lectin galactoside-binding soluble 1 , S-Lac lectin 1 , beta-galactoside binding protein , beta-galactoside-binding lectin L-14-I , galaptin , lactose-binding lectin 1 , lectin galactoside-binding soluble 1 , 14 kDa laminin-binding protein , HBL , HLBP14 , HPL , beta-galactoside-binding protein 14kDa , gal-1 , putative MAPK-activating protein PM12 , RL 14.5 , lectin, galactose binding, soluble 1

100069841 Equus caballus
379433 Xenopus laevis
742148 Pan troglodytes
396491 Gallus gallus
408848 Apis mellifera
6012550 Coprinopsis cinerea okayama7130
6012551 Coprinopsis cinerea okayama7#130
6012552 Coprinopsis cinerea okayama7130
100196938 Papio anubis
443298 Ovis aries
100751963 Cricetulus griseus
16852 Mus musculus
3956 Homo sapiens
326598 Bos taurus
414915 Sus scrofa
56646 Rattus norvegicus
610276 Canis lupus familiaris
100722354 Cavia porcellus
100173289 Pongo abelii
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