LGALS1/Galectin 1 Protein (AA 2-135) (Fc Tag)
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- Target See all LGALS1/Galectin 1 (LGALS1) Proteins
- LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 2-135
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This LGALS1/Galectin 1 protein is labelled with Fc Tag.
- Purpose
- Human Galectin 1 Protein
- Sequence
- Ala2-Asp135
- Characteristics
- Recombinant Human Galectin 1 Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Ala2-Asp135.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human GAL1, hFc Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Biotinylated Anti-GAL1 Antibody, hFc Tag with the EC50 of 40.6ng/ml determined by ELISA. See testing image for detail.
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Lectin, Galactoside-Binding, Soluble, 1 (LGALS1) (AA 2-135) protein (His tag)
Crystallography grade LGALS1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Lectin, Galactoside-Binding, Soluble, 1 (LGALS1) (AA 2-135) protein (Fc Tag)LGALS1 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Lectin, Galactoside-Binding, Soluble, 1 (LGALS1) (AA 1-135) protein (GST tag)LGALS1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Lectin, Galactoside-Binding, Soluble, 1 (LGALS1) (AA 1-100) protein (GST tag)LGALS1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Lectin, Galactoside-Binding, Soluble, 1 (LGALS1) (AA 2-135) protein (His tag)Crystallography grade LGALS1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))
- Alternative Name
- GAL1 (LGALS1 Products)
- Synonyms
- GAL1 Protein, GBP Protein, Galectin-1 Protein, LGAS1 Protein, LGALS1 Protein, MGC64502 Protein, GB10026 Protein, AA410090 Protein, Gal-1 Protein, Galbp Protein, L-14.5 Protein, L14 Protein, Lect14 Protein, galectin-1 Protein, Galaptin Protein, galectin 1 Protein, galectin-1 Protein, lectin, galactoside-binding, soluble, 1 L homeolog Protein, protein enabled Protein, lectin, galactose binding, soluble 1 Protein, LGALS1 Protein, Lgals1 Protein, CC1G_05003 Protein, CC1G_05004 Protein, lgals1.L Protein, LOC408848 Protein
- Background
- Galectin 1(Gal-1), a β-galactoside binding mammalian lectin of 14KDa, is implicated in many signalling pathways, immune responses associated with cancer progression and immune disorders. Inhibition of human Gal-1 has been regarded as one of the potential therapeutic approaches for the treatment of cancer, as it plays a major role in tumour development and metastasis by modulating various biological functions viz. apoptosis, angiogenesis, migration, cell immune escape.
- Molecular Weight
- 41.9 kDa. Due to glycosylation, the protein migrates to 48-55 kDa based on Tris-Bis PAGE result.
- UniProt
- P09382
- Pathways
- Carbohydrate Homeostasis
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