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Browse our SPNA2 (SPNA2) ELISA Kits

Full name:
alpha-Spectrin 2 ELISA Kits (SPNA2)
On www.antibodies-online.com are 1 alpha-Spectrin 2 (SPNA2) ELISA Kits from 1 different suppliers available. Additionally we are shipping and many more products for this protein. A total of 2 SPNA2 products are currently listed.
Synonyms:
2610027H02Rik, A2a, EIEE5, IPF, NEAS, Spna-2, Spna2, SPTA2
list all ELISA KIts Gene Name GeneID UniProt
SPNA2 20740  
Human SPNA2 SPNA2 6709 Q13813
Rat SPNA2 SPNA2 64159 P16086

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SPNA2 (SPNA2) ELISA Kits by Reactivity

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More ELISA Kits for SPNA2 Interaction Partners

Mouse (Murine) alpha-Spectrin 2 (SPNA2) interaction partners

  1. Fodrin is a regulatory transporter of gamma-tubulin (show TUBG1 ELISA Kits) to the centrosomes for normal progression of mitosis.

  2. Mena/VASP and alphaII-Spectrin complexes regulate cytoplasmic actin networks in cardiomyocytes and protect from conduction abnormalities and dilated cardiomyopathy.

  3. Degradation of Spna2 by calpain- and/or caspase is not central to the pathogenesis of 1,2-diacetylbenzene (DAB) axonopathy.

  4. The present study demonstrates the age-dependent intraneuronal presence of an alphaII-spectrin cleavage fragment in mammalian forebrain which is exacerbated in a transgenic model of AD.

  5. alphaII-spectrin deficiency is embryonic lethal, with cardiac, craniofacial and neural tube malformations.

  6. Results of this study provide evidence for a role for spectrin in different steps of megakaryocyte development through its participation in the formation of invaginated membranes and in the maintenance of proplatelet structure.

  7. When cleaved into a 120-kDa product by apoptotic proteases in salivary gland cells in vitro, alpha-fodrin (show SPTAN1 ELISA Kits) is a successful pathogenic autoantigen for development of autoimmune exocrinopathy in the Sjogren syndrome model.

  8. In heart muscle, alphaII-spectrin is located within the contractile fibres near the Z-disc as well as on the cardiomyocyte plasma membrane.

  9. support a critical role for the alphaII-spectrin-SH3i isoform of spectrin in intracellular targeting of connexin 43 (show GJA1 ELISA Kits) to gap junctions

  10. AlphaII-spectrin-VASP complexes regulate cortical actin cytoskeleton assembly with implications for vascular permeability.

Human alpha-Spectrin 2 (SPNA2) interaction partners

  1. These results suggest that ubiquitin C-terminal hydrolase and alphaII-spectrin breakdown product 145 kDa may be useful in assessing outcome after pediatric traumatic brain injury.

  2. Variations in both alpha-spectrin (show SPTAN1 ELISA Kits) (SPTA1 (show SPTA1 ELISA Kits)) and beta-spectrin ( SPTB (show SPTB ELISA Kits) ) were found in a neonate with prolonged jaundice in a family where nine individuals had hereditary elliptocytosis.

  3. aggressiveness of MLH1 (show MLH1 ELISA Kits)-positive colorectal cancers might be related to SPTAN1 (show SPTAN1 ELISA Kits).

  4. hypomyelination of the cerebral white matter was revealed at the age of 1 year, and a de novo heterozygous mutation in the SPTAN1 (show SPTAN1 ELISA Kits) gene was confirmed

  5. loss of SPTAN1 (show SPTAN1 ELISA Kits) switches TGF-beta (show TGFB1 ELISA Kits) signaling from tumor suppression to tumor promotion by engaging Notch (show NOTCH1 ELISA Kits) signaling and activating SOX9 (show SOX9 ELISA Kits) in esophageal adenocarcinoma.

  6. organization of a spectrin-like cytoskeleton is associated with keratinocyte differentiation, and cytoskeleton disruption is mediated by either PKCdelta (show PKCd ELISA Kits)(Thr505) phosphorylation associated with phosphorylated adducin or due to reduction of endogenous adducin

  7. In-frame mutations in the C-terminus of SPTAN1 (show SPTAN1 ELISA Kits) cause a core set of manifestations that include severe intellectual disability, generalized epilepsy, and pontocerebellar atrophy.

  8. Analysis of alphaII-spectrin breakdown products in cerebrospinal fluid predicts mortality and injury severity in adults following traumatic brain injury.

  9. findings suggest that pathological aggregation of alpha/beta spectrin heterodimers and abnormal axon initial segment(AIS (show AR ELISA Kits)) integrity resulting from SPTAN1 (show SPTAN1 ELISA Kits) mutations were involved in pathogenesis of infantile epilepsy

  10. Fanconi anemia (show PALB2 ELISA Kits) proteins may play an important role in maintaining the stability of alphaIISp in the cell by regulating its cleavage by mu-calpain (show CAPNL1 ELISA Kits).

SPNA2 Antigen Profile

Antigen Summary

Spectrins are a family of filamentous cytoskeletal proteins that function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. This gene encodes an alpha spectrin that is specifically expressed in nonerythrocytic cells. The encoded protein has been implicated in other cellular functions including DNA repair and cell cycle regulation. Mutations in this gene are the cause of early infantile epileptic encephalopathy-5. Alternate splicing results in multiple transcript variants.

Alternative names and synonyms associated with SPNA2

  • spectrin alpha, non-erythrocytic 1 (Sptan1) Elisa Kit
  • spectrin, alpha, non-erythrocytic 1 (SPTAN1) Elisa Kit
  • spectrin, alpha, non-erythrocytic 1 (Sptan1) Elisa Kit
  • 2610027H02Rik Elisa Kit
  • A2a Elisa Kit
  • EIEE5 Elisa Kit
  • IPF Elisa Kit
  • NEAS Elisa Kit
  • Spna-2 Elisa Kit
  • Spna2 Elisa Kit
  • SPTA2 Elisa Kit

Protein level used designations for alpha-Spectrin 2 (SPNA2) ELISA Kits

alpha-II spectrin , alpha-fodrin , alpha-spectrin 2, brain , fodrin alpha chain , spectrin alpha 2 , spectrin alpha chain, brain , spectrin alpha chain, non-erythrocytic 1 , spectrin, non-erythroid alpha chain , spectrin, non-erythroid alpha subunit , a--fodrin , alpha II spectrin , alpha-spectrin 2 , brain alpha-spectrin , inhibitory protein factor , noerythroid alpha-spectrin 2 , nonerythroid alpha-spectrin 2

GENE ID SPECIES
20740 Mus musculus
6709 Homo sapiens
64159 Rattus norvegicus
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