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SPTAN1 Products

(Spectrin alpha Chain, Brain (SPTAN1))
Spectrins are a family of filamentous cytoskeletal proteins that function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. This gene encodes an alpha spectrin that is specifically expressed in nonerythrocytic cells. The encoded protein has been implicated in other cellular functions including DNA repair and cell cycle regulation. Mutations in this gene are the cause of early infantile epileptic encephalopathy-5. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Sep 2010].

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Featured SPTAN1 Categories

SPTAN1 Antibodies

High quality antibodies with extensive validation data.

SPTAN1 ELISA Kits

Reliable ELISA kits for a wide range of species.

SPTAN1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SPTAN1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (1)
  • (6)
Cat. No. ABIN6148403
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7438451
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC
Validations
  • (6)
Cat. No. ABIN7234066
Quantity 200 μL
Datasheet Datasheet

Recommended SPTAN1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970386
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6962314
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959657
Quantity 96 tests
Datasheet Datasheet

Recommended SPTAN1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7401065
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7389866
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7400978
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our SPTAN1 products

Li, Pierre, Yang, Nguyen, Johnson, Venetucci, Torres, Lucke-Wold, Shi, Boutte, Shear, Leung, Wang: "Blood-Based Brain and Global Biomarker Changes after Combined Hypoxemia and Hemorrhagic Shock in a Rat Model of Penetrating Ballistic-Like Brain Injury." in: Neurotrauma reports, Vol. 2, Issue 1, pp. 370-380, (2021) (PubMed).

Ainola, Porola, Takakubo, Przybyla, Kouri, Tolvanen, Hänninen, Nordström: "Activation of plasmacytoid dendritic cells by apoptotic particles - mechanism for the loss of immunological tolerance in Sjögren's syndrome." in: Clinical and experimental immunology, Vol. 191, Issue 3, pp. 301-310, (2019) (PubMed).

Meng, Zhang, Shi, Zhang, Yuan: "Inhibition of interleukin-6 abolishes the promoting effects of pair housing on post-stroke neurogenesis." in: Neuroscience, Vol. 307, pp. 160-70, (2016) (PubMed).

Nicolas, Fournier, Galand, Malbert-Colas, Bournier, Kroviarski, Bourgeois, Camonis, Dhermy, Grandchamp, Lecomte: "Tyrosine phosphorylation regulates alpha II spectrin cleavage by calpain." in: Molecular and cellular biology, Vol. 22, Issue 10, pp. 3527-36, (2002) (PubMed).

Hu, Watanabe, Bennett: "Characterization of human brain cDNA encoding the general isoform of beta-spectrin." in: The Journal of biological chemistry, Vol. 267, Issue 26, pp. 18715-22, (1992) (PubMed).

Moon, McMahon: "Generation of diversity in nonerythroid spectrins. Multiple polypeptides are predicted by sequence analysis of cDNAs encompassing the coding region of human nonerythroid alpha-spectrin." in: The Journal of biological chemistry, Vol. 265, Issue 8, pp. 4427-33, (1990) (PubMed).

Synonyms and alternative names related to SPTAN1

spectrin alpha, non-erythrocytic 1 (SPTAN1), spectrin alpha, non-erythrocytic 1 (sptan1), spectrin alpha, non-erythrocytic 1 (Sptan1), spectrin, alpha, non-erythrocytic 1 (Sptan1), 2610027H02Rik, A2a, EIEE5, im:7157190, IPF, NEAS, SPECA, Spna-2, Spna2, SPTA2, wu:fa20e05, wu:fb33g08, wu:fk32a10, zgc:112229

Protein level used designations for SPTAN1

  • alpha-fodrin
  • spectrin alpha chain, brain
  • spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)
  • cardiomyocyte alpha-spectrin
  • sequence with a GC signal
  • alpha2 spectrin
  • Spectrin alpha chain, brain
  • alpha-II spectrin
  • alpha-spectrin 2, brain
  • fodrin alpha chain
  • spectrin alpha 2
  • spectrin alpha chain, non-erythrocytic 1
  • spectrin, non-erythroid alpha chain
  • spectrin, non-erythroid alpha subunit
  • a--fodrin
  • alpha II spectrin
  • alpha-spectrin 2
  • brain alpha-spectrin
  • inhibitory protein factor
  • noerythroid alpha-spectrin 2
  • nonerythroid alpha-spectrin 2
  • alpha-spectrin
  • nonerythroid alpha-spectrin
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