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Browse our Occludin Proteins (OCLN)

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Occludin Proteins (OCLN)
On are 9 Occludin (OCLN) Proteins from 5 different suppliers available. Additionally we are shipping Occludin Antibodies (116) and Occludin Kits (42) and many more products for this protein. A total of 178 Occludin products are currently listed.
AI503564, BLCPMG, Ocl, ocln, oclnb, tpmt, wu:fd23h10, wu:fi13c01, zgc:56359, zgc:113992
list all proteins Gene Name GeneID UniProt
OCLN 4950  
OCLN 18260 Q61146
Rat OCLN OCLN 83497 Q6P6T5

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Occludin Proteins (OCLN) by Origin

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More Proteins for Occludin Interaction Partners

Human Occludin (OCLN) interaction partners

  1. Study provides evidence that occludin contributes to the regulation of size-reductive proliferation and epithelial cell maturation in a phosphorylation-dependent manner.

  2. Report shows that silencing MARCH3 (show MARCH3 Proteins) protects the endothelial barrier and upregulates OCLN in MARCH3 (show MARCH3 Proteins)-depleted cells. MARCH3 (show MARCH3 Proteins) silencing results in the strengthening of cell-cell contacts and inactivates FoxO1 (show FOXO1 Proteins).

  3. STAT3 activation downregulates the ZO-1 and occludin levels and increases the endothelial permeability through the induction of VEGF production in retinal endothelial cells.

  4. Downregulation of OCLN is associated with clear cell renal cell carcinoma (show MOK Proteins).

  5. These data suggest that the Rho/ROCK signaling pathway is involved in HIV-1 Tat (show TAT Proteins)-mediated changes in occludin, RAGE (show AGER Proteins), and LRP1 (show LRP1 Proteins) in human cerebral microvascular endothelial cells cells.

  6. OCLN is essential for HCV infection of human hepatic cells.

  7. OCLN and ZO1 (show TJP1 Proteins) levels appear to be early prognostic markers in patients suffering from sepsis.

  8. autotypic tight junctions molecular composition, like claudin-1 (show CLDN7 Proteins) and occludin expression could influence the demyelinating process by altering the permeability of the blood-nerve barrier.

  9. Occludin expression has a clear relationship with bone metastasis in human cancer.

  10. This is report of a family of Indian origin with two affected sibs and segregation of a homozygous novel OCLN mutation in the exon 3(NG_028291.1(OCLN_v001):c.252delC).

Cow (Bovine) Occludin (OCLN) interaction partners

  1. ADMA has potent adverse effects on cell proliferation, intracellular ROS (show ROS1 Proteins) generation, cell permeability, levels of ICAM-1 (show ICAM1 Proteins), and the tight-junction protein occludin

  2. the presence of occludin at the membrane is dependent in part on calcium-sensitive signaling cascades

  3. cyclic strain modulates both the expression and phosphorylation state of occludin and ZO-1 (show TJP1 Proteins) in vascular endothelial cells, with putative consequences for endothelial tight junction assembly and barrier integrity

  4. These data demonstrate a novel mechanism of VEGF (show VEGFA Proteins)-induced occludin phosphorylation and ubiquitination that contributes to TJ trafficking and subsequent vascular permeability.

Mouse (Murine) Occludin (OCLN) interaction partners

  1. STAT3 activation downregulates the ZO-1 and occludin levels and increases the endothelial permeability through the induction of VEGF production in retinal endothelial cells.

  2. Tricellulin (show MARVELD2 Proteins) is a specific redox sensor and sealing element at 3-cell contacts and may compensate as a redox mediator for occludin loss at 2-cell contacts in vivo and in vitro.

  3. These findings provide evidence for occludin playing a role in the invasion of Toxoplasma gondii in small intestinal epithelial cells.

  4. occludin deficiency increases susceptibility to ethanol-induced colonic mucosal barrier dysfunction and liver damage in mice.

  5. PHD3 (show EGLN3 Proteins) protects intestinal epithelial barrier function and reveal a hydroxylase-independent function of PHD3 (show EGLN3 Proteins) in stabilizing occludin

  6. Zonula occludens-1 (show TJP1 Proteins), occludin and E-cadherin (show CDH1 Proteins) expression and organization in salivary glands

  7. Our study demonstrates spatiotemporal alterations in occludin mRNA- and protein-expression, indicating that Cx43 (show GJA1 Proteins) might act as a regulator for blood-testis-barrier

  8. Occludin and Claudin-1 (show CLDN1 Proteins) expressions in the large intestine are under the circadian control, which is associated with temporal regulation of colonic permeability and also susceptibility to colitis.

  9. Hypoxic induction of CAV1 (show CAV1 Proteins) in the colon was essential for intestinal barrier integrity by regulating occludin expression.

  10. Activation of RhoA (show RHOA Proteins)/ROCK1 (show ROCK1 Proteins) by high glucose in diabetic nephropathy disrupts the expression and translocation of occludin/ZO-1 (show TJP1 Proteins), which can be corrected by simvastatin.

Pig (Porcine) Occludin (OCLN) interaction partners

  1. ZO-1 (show TJP1 Proteins) and occludin are expressed in oocytes and preimplantation embryos, and that ZO-1alpha+ is transcribed by zygotic gene activation and translated from early blastocysts with prominent increase of occludin at the blastocyst stage.

Rabbit Occludin (OCLN) interaction partners

Occludin (OCLN) Protein Profile

Protein Summary

This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5.

Alternative names and synonyms associated with Occludin (OCLN)

  • occludin (OCLN)
  • occludin (ocln)
  • occludin (Ocln)
  • occludin (ocln-b)
  • occludin a (oclna)
  • AI503564 protein
  • BLCPMG protein
  • Ocl protein
  • ocln protein
  • oclnb protein
  • tpmt protein
  • wu:fd23h10 protein
  • wu:fi13c01 protein
  • zgc:56359 protein
  • zgc:113992 protein

Protein level used designations for Occludin Proteins (OCLN)

occludin , tight junction protein occludin TM4 minus , thiopurine methyltransferase , occludin-like , tight junction protein occludin , tight-junction protein , occludin b

100073306 Equus caballus
4950 Homo sapiens
548702 Xenopus (Silurana) tropicalis
700504 Macaca mulatta
741925 Pan troglodytes
100031291 Monodelphis domestica
100077299 Ornithorhynchus anatinus
100386012 Callithrix jacchus
100462976 Oncorhynchus mykiss
100583496 Nomascus leucogenys
100506658 Homo sapiens
403844 Canis lupus familiaris
512405 Bos taurus
18260 Mus musculus
83497 Rattus norvegicus
398133 Xenopus laevis
397236 Sus scrofa
100527952 Cavia porcellus
100338492 Oryctolagus cuniculus
396026 Gallus gallus
443201 Ovis aries
100174190 Pongo abelii
405757 Danio rerio
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