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Occludin Protein (OCLN) (Myc-DYKDDDDK Tag)

OCLN Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2727862
  • Target See all Occludin (OCLN) Proteins
    Occludin (OCLN)
    Protein Type
    Recombinant
    Origin
    • 5
    • 3
    • 2
    Human
    Source
    • 6
    • 2
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This Occludin protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Occludin protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product OCLN Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    Occludin (OCLN)
    Alternative Name
    Occludin (OCLN Products)
    Synonyms
    AI503564 Protein, Ocl Protein, ocln Protein, oclnb Protein, tpmt Protein, OCLN Protein, wu:fd23h10 Protein, wu:fi13c01 Protein, zgc:113992 Protein, zgc:56359 Protein, BLCPMG Protein, occludin Protein, occludin S homeolog Protein, occludin a Protein, Ocln Protein, OCLN Protein, ocln.S Protein, ocln Protein, oclna Protein
    Background
    This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5.
    Molecular Weight
    59 kDa
    NCBI Accession
    NP_002529
    Pathways
    Cell-Cell Junction Organization, Hepatitis C
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