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Browse our TGFB2 Proteins (TGFB2)

Full name:
Transforming Growth Factor, beta 2 Proteins (TGFB2)
On www.antibodies-online.com are 53 Transforming Growth Factor, beta 2 (TGFB2) Proteins from 15 different suppliers available. Additionally we are shipping TGFB2 Antibodies (138) and TGFB2 Kits (92) and many more products for this protein. A total of 296 TGFB2 products are currently listed.
Synonyms:
BB105277, LDS4, MGF, TGF-B2, TGF-beta 2, tgf-beta2, Tgfb-2, TGFB2, tgfb2-A, TGFbeta2, Tgfbr2T
list all proteins Gene Name GeneID UniProt
TGFB2 7042 P61812
TGFB2 21808 P27090
TGFB2 81809 Q07257

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TGFB2 Proteins (TGFB2) by Origin

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Top referenced TGFB2 Proteins

  1. Human TGFB2 Protein expressed in Escherichia coli (E. coli) - ABIN2667582 : Bian, Elner, Elner: Regulation of VEGF mRNA expression and protein secretion by TGF-beta2 in human retinal pigment epithelial cells. in Experimental eye research 2007 (PubMed)
    Show all 8 references for ABIN2667582

  2. Human TGFB2 Protein expressed in Nicotiana benthamiana - ABIN1112028 : ten Dijke, Hansen, Iwata, Pieler, Foulkes: Identification of another member of the transforming growth factor type beta gene family. in Proceedings of the National Academy of Sciences of the United States of America 1988 (PubMed)
    Show all 4 references for ABIN1112028

  3. Human TGFB2 Protein expressed in Escherichia coli (E. coli) - ABIN1047764 : de Martin, Haendler, Hofer-Warbinek, Gaugitsch, Wrann, Schlüsener, Seifert, Bodmer, Fontana, Hofer: Complementary DNA for human glioblastoma-derived T cell suppressor factor, a novel member of the transforming growth factor-beta gene family. in The EMBO journal 1988 (PubMed)
    Show all 3 references for ABIN1047764

More Proteins for TGFB2 Interaction Partners

Zebrafish Transforming Growth Factor, beta 2 (TGFB2) interaction partners

  1. The results of this study found that Bptf and TGF-beta (show TGFB1 Proteins)/Smad2 (show SMAD2 Proteins) mediate nucleosome remodeling to regulate wnt8a (show WNT8A Proteins) expression and hence neural posteriorization.

  2. Functional investigation of a subset of these genes, fgf10a (show FGF10 Proteins), tgfb2, pax9 (show PAX9 Proteins), and smad5 (show SMAD5 Proteins) revealed their necessity in zebrafish palatogenesis.

  3. These data suggest Pez (show PTPN14 Proteins) plays a crucial role in organogenesis by inducing TGFbeta (show TGFB1 Proteins) and epithelial-mesenchymal transition.

Human Transforming Growth Factor, beta 2 (TGFB2) interaction partners

  1. findings indicate that lncRNA-ATB governs the autocrine secretion of TGF-beta2 in KFs (show GDF6 Proteins), at least in part, by downregulating the expression level of ZNF217 via miR (show MLXIP Proteins)-200c, suggesting a signaling axis consisting of lncRNA-ATB/miR (show MLXIP Proteins)-200c/ZNF217/TGF-beta2

  2. association between SNP rs6658835 in TGF-beta2 and conotruncal heart defects

  3. miR (show MLXIP Proteins)-422a directly targeted TGFbeta2 and regulated its expression and the activation of downstream molecules, smad2 (show SMAD2 Proteins) and smad3 (show SMAD3 Proteins) in osteosarcoma cells.

  4. miR (show MLXIP Proteins)-378a expression is associated with its methylation status in TGF-beta1 (show TGFB1 Proteins)-treated cells, and epigenetically-regulated miR (show MLXIP Proteins)-378a inhibits TGF-beta1 (show TGFB1 Proteins)-induced hepatic stellate cells activation, at least in part, via TGF-beta2.

  5. we detected and verified a list of differentially expressed microRNAs in PE placentas by HTS (show APCDD1 Proteins) and qRT-PCR, and provided preliminary evidence for the role of miR (show MLXIP Proteins)-193b-3p in the pathogenesis of preeclampsia by targeting TGF-beta2.

  6. Likely pathogenic variants included a TGFB2 variant in one patient and a SMAD3 (show SMAD3 Proteins) variant in another. These variants have been reported previously in individuals with similar phenotypes. Variants of uncertain significance of particular interest included novel variants in MYLK (show MYLK Proteins) and MFAP5 (show MFAP5 Proteins), which were identified in a third patient

  7. Results provide evidence that miR (show MLXIP Proteins)-148a decreases the expression of TGFbeta2 and SMAD2 (show SMAD2 Proteins) in gastric cancer cells through binding to their 3'UTRs.

  8. TGF-beta2 induces epithelial-mesenchymal transition by activating the PI3K (show PIK3CA Proteins)/Akt (show AKT1 Proteins)/mTOR (show FRAP1 Proteins) signaling pathway in cultured human lens epithelial cells.

  9. Human retinal pigment epithelial cells were cultured in the presence or absence of TGF-beta2, and reverse-transcription quantitative PCR was performed to determine the mRNA expression of IDO (show IDO1 Proteins) and Nrf2 (show GABPA Proteins).

  10. TGF-beta2 induces Grb2 (show GRB2 Proteins) to recruit PI3-K (show PIK3CA Proteins) to TGF-RII that activates JNK (show MAPK8 Proteins)/AP-1 (show FOSB Proteins)-signaling and augments invasiveness of Theileria-transformed macrophages.

Mouse (Murine) Transforming Growth Factor, beta 2 (TGFB2) interaction partners

  1. These data provide new insights in the molecular interaction between Fibulin-4 (show FBLN4 Proteins) and TGF-beta (show TGFB1 Proteins) pathway regulation in the pathogenesis of aortic aneurysms.

  2. APC (show APC Proteins)-derived TSP-1 (show GZMA Proteins) is essential for the development of an adaptive regulatory immune response induced by TGF-beta2-expressing APCs (show APCS Proteins) similar to those located at mucosal and ocular sites.

  3. Epidermal Tgfb2 controls proliferation, differentiation and ECM (show MMRN1 Proteins) production by reticular fibroblasts.

  4. Pathological TGF-beta (show TGFB1 Proteins) release from osteolytic bone metastases contributes to muscle weakness in cancer by decreasing Ca(2 (show CA2 Proteins)+)-induced muscle force production.

  5. Thus, along with TGF-b and MAPK signaling, NFkappaB serves as an important regulatory pathway which following Losartan treatment

  6. Expression of TGFbeta2 was induced in response to elevated canonical Wnt (show WNT2 Proteins) signaling in dystrophic muscles and that the resulting increase in TGFbeta (show TGFB1 Proteins) activity affected the behavior of satellite cells in an autocrine or paracrine fashion.

  7. these data shed light on previously unrecognized roles of Mkx (show MKX Proteins) in tendinopathy, tenogenesis, and tendon repair as well as in regulating the TGFbeta (show TGFB1 Proteins) pathway.

  8. TGFbeta2 regulates hypothalamic TRH expression through TIEG1 during fetal development.

  9. These findings indicate that the lens epithelium of MCT (show MCAT Proteins) mice has increased expression of TGFb1 (show TGFB1 Proteins) and Tgfb2 before cataract affection and that changes in the expression of FGF2 (show FGF2 Proteins) as well as TGFbeta (show TGFB1 Proteins) may contribute to the progression of the cataract in the mice.

  10. Endothelial lineage differentiation from induced pluripotent stem cells is regulated by microRNA-21 and transforming growth factor beta2 (TGF-beta2) pathways

Cow (Bovine) Transforming Growth Factor, beta 2 (TGFB2) interaction partners

  1. Data show that TGF-beta pathways operate during ovarian fetal development, and fibrillin 3 is highly expressed at a critical stage early in developing human and bovine fetal ovaries.

Pig (Porcine) Transforming Growth Factor, beta 2 (TGFB2) interaction partners

  1. Suggest that the interplay between TGFbeta (show TGFB1 Proteins)-2 and LPS (show IRF6 Proteins) regulates the levels of IL-8 (show IL8 Proteins) in the immature newborn intestine.

  2. TGFbeta (show TGFB1 Proteins) may play a role in the overall process of luteinization, but it appears not to influence steroidogenesis in luteinizing pig follicles.

Rabbit Transforming Growth Factor, beta 2 (TGFB2) interaction partners

  1. There was no significant change in the expression of TGF-beta(2) and alpha-SMA (show SMN1 Proteins) after laser-assisted intrastromal scanning.

TGFB2 Protein Profile

Protein Summary

This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types by transducing their signal through combinations of transmembrane type I and type II receptors (TGFBR1 and TGFBR2) and their downstream effectors, the SMAD proteins. Disruption of the TGFB/SMAD pathway has been implicated in a variety of human cancers. The encoded protein is secreted and has suppressive effects of interleukin-2 dependent T-cell growth. Translocation t(1\;7)(q41\;p21) between this gene and HDAC9 is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. The knockout mice lacking this gene show perinatal mortality and a wide range of developmental, including cardiac, defects. Alternatively spliced transcript variants encoding different isoforms have been identified.

Alternative names and synonyms associated with TGFB2

  • transforming growth factor, beta 2 (TGFB2)
  • transforming growth factor, beta 2 (tgfb2)
  • transforming growth factor, beta 2 (Tgfb2)
  • transforming growth factor, beta receptor II (Tgfbr2)
  • BB105277 protein
  • LDS4 protein
  • MGF protein
  • TGF-B2 protein
  • TGF-beta 2 protein
  • tgf-beta2 protein
  • Tgfb-2 protein
  • TGFB2 protein
  • tgfb2-A protein
  • TGFbeta2 protein
  • Tgfbr2T protein

Protein level used designations for TGFB2

transforming growth factor beta-2 , tgf beta 2 , transforming growth factor, beta 2 , transforming growth factor beta-2-like , BSC-1 cell growth inhibitor , G-TSF , cetermin , glioblastoma-derived T-cell suppressor factor , polyergin , TGF-beta-2 , TGF beta 2 protein , milk growth factor , transforming growth factor beta 2 , Transforming growth factor beta-2 , transforming growth factor-beta 2 , transforming growth factor-beta2 , TGF-beta 2 , prepro-polypeptide , TGF-beta receptor type II , TGF-beta receptor type-2 , TGF-beta type II receptor , TGFR-2 , tbetaR-II , transforming growth factor beta receptor type II , transforming growth factor beta, receptor 2 , transforming growth factor, beta receptor 2 , transforming growth factor, beta receptor IIT , transforming growth factor-b type II receptor , transforming growth factor-beta receptor type II , transforming growth factor-beta type II receptor

GENE ID SPECIES
707540 Macaca mulatta
369194 Danio rerio
457742 Pan troglodytes
100390586 Callithrix jacchus
100461291 Pongo abelii
100596183 Nomascus leucogenys
7042 Homo sapiens
21808 Mus musculus
81809 Rattus norvegicus
534069 Bos taurus
488596 Canis lupus familiaris
397084 Sus scrofa
100009371 Oryctolagus cuniculus
100720726 Cavia porcellus
421352 Gallus gallus
554322 Ovis aries
373801 Xenopus laevis
81810 Rattus norvegicus
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