Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

SMAD4 Proteins

(SMAD Family Member 4 (SMAD4))
This gene encodes a member of the Smad family of signal transduction proteins. Smad proteins are phosphorylated and activated by transmembrane serine-threonine receptor kinases in response to TGF-beta signaling. The product of this gene forms homomeric complexes and heteromeric complexes with other activated Smad proteins, which then accumulate in the nucleus and regulate the transcription of target genes. This protein binds to DNA and recognizes an 8-bp palindromic sequence (GTCTAGAC) called the Smad-binding element (SBE). The Smad proteins are subject to complex regulation by post-translational modifications. Mutations or deletions in this gene have been shown to result in pancreatic cancer, juvenile polyposis syndrome, and hereditary hemorrhagic telangiectasia syndrome. [provided by RefSeq, Oct 2009].
SMAD4 Protein (AA 13-227) (His tag) SMAD4 Protein (AA 13-227) (His tag) SMAD4 Protein (AA 13-227) (His tag) (ABIN7125119)

SMAD4 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA

SMAD4 Protein (AA 1-551) (His tag) SMAD4 Protein (AA 1-551) (His tag) SMAD4 Protein (AA 1-551) (His tag) (ABIN3134713)

Crystallography grade SMAD4 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys

SMAD4 Protein (AA 1-552) (His tag) SMAD4 Protein (AA 1-552) (His tag) SMAD4 Protein (AA 1-552) (His tag) (ABIN3095493)

Crystallography grade SMAD4 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys

SMAD4 Proteins by Grade

Find SMAD4 Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

SMAD4 Proteins by Origin

Find SMAD4 Proteins for a variety of species such as anti-Human SMAD4, anti-Mouse SMAD4, anti-Rat SMAD4. The species listed below are among those available. Click on a link to go to the corresponding products.

SMAD4 Proteins by Source

Here you will find SMAD4 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

SMAD4 Proteins by Protein Type

Here you can find SMAD4 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

SMAD4 Proteins by Application

Find SMAD4 Proteins validated for a specific application such as WB, ELISA, SDS, PC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular SMAD4 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125119
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3134713
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3095493
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN1692097
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7319042
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7395287
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7413811
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1320605
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
  • (1)
Cat. No. ABIN2732222
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1320607
Quantity 10 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2751533
Quantity 5 applications
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN6700538
Quantity 50 μg
Datasheet Datasheet
Reactivity Rat
Source Yeast
Validations
Cat. No. ABIN1475622
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our SMAD4 Proteins

Atanelishvili, Shirai, Akter, Buckner, Noguchi, Silver, Bogatkevich: "M10, a caspase cleavage product of the hepatocyte growth factor receptor, interacts with Smad2 and demonstrates antifibrotic properties in vitro and in vivo." in: Translational research : the journal of laboratory and clinical medicine, Vol. 170, pp. 99-111, (2016) (PubMed).

Iempridee, Das, Xu, Mertz: "Transforming growth factor beta-induced reactivation of Epstein-Barr virus involves multiple Smad-binding elements cooperatively activating expression of the latent-lytic switch BZLF1 gene." in: Journal of virology, Vol. 85, Issue 15, pp. 7836-48, (2011) (PubMed).

Aliases for SMAD4 Proteins

SMAD family member 4 (SMAD4) Proteins
Smad4 protein (smad4) Proteins
SMAD family member 4 (Smad4) Proteins
SMAD family member 4, gene 1 L homeolog (smad4.1.L) Proteins
AW743858 Proteins
D18Wsu70e Proteins
DPC4 Proteins
dpc4 Proteins
JIP Proteins
jip Proteins
MADH4 Proteins
Madh4 Proteins
madh4 Proteins
MYHRS Proteins
smad4 Proteins
Xsmad4 Proteins
xsmad4a Proteins
XSmad4alpha Proteins
You are here:
Support