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Browse our anti-GBA (GBA) Antibodies

Full name:
anti-Glucosidase, Beta, Acid Antibodies (GBA)
On www.antibodies-online.com are 86 Glucosidase, Beta, Acid (GBA) Antibodies from 15 different suppliers available. Additionally we are shipping GBA Proteins (30) and GBA Kits (20) and many more products for this protein. A total of 143 GBA products are currently listed.
Synonyms:
BETA-GLUCOSIDASE, betaGC, beta glucosidase 25, GBA1, GC, GCase, GCB, GLUC, PSPTO3318, PSPTO4290, T12J13.8, T12J13_8
list all antibodies Gene Name GeneID UniProt
GBA 684536  
GBA 2629 P04062
GBA 14466 P17439

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Most Popular Reactivities for anti-GBA (GBA) Antibodies

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anti-Rat (Rattus) GBA Antibodies:

anti-Human GBA Antibodies:

anti-Mouse (Murine) GBA Antibodies:

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Top referenced anti-GBA Antibodies

  1. Human Monoclonal GBA Primary Antibody for IF, WB - ABIN394481 : Dos Santos, Pestana, Diniz, Campos, Abdalla-Carvalho, de Rosso, Pereira, Nicaretta, de Carvalho, Dos Santos, Santos-Rebouças, Pimentel: Mutational analysis of GIGYF2, ATP13A2 and GBA genes in Brazilian patients with early-onset Parkinson's disease. in Neuroscience letters 2010 (PubMed)
    Show all 5 references for ABIN394481

  2. Human Monoclonal GBA Primary Antibody for IF, IHC (p) - ABIN561009 : Campeau, Rafei, Boivin, Sun, Grabowski, Galipeau: Characterization of Gaucher disease bone marrow mesenchymal stromal cells reveals an altered inflammatory secretome. in Blood 2009 (PubMed)
    Show all 5 references for ABIN561009

  3. Human Polyclonal GBA Primary Antibody for ICC, IF - ABIN442242 : Zancan, Bellesso, Costa, Salvalaio, Stroppiano, Hammond, Argenton, Filocamo, Moro: Glucocerebrosidase deficiency in zebrafish affects primary bone ossification through increased oxidative stress and reduced Wnt/β-catenin signaling. in Human molecular genetics 2015 (PubMed)

More Antibodies against GBA Interaction Partners

Arabidopsis thaliana Glucosidase, Beta, Acid (GBA) interaction partners

  1. Results describe the characterization of a beta-glucosidase homolog from Arabidopsis thaliana.

Human Glucosidase, Beta, Acid (GBA) interaction partners

  1. The anti-enterovirus 71 activity of GBA1 was bimodal: endogenous GBA1 restricted cell surface expression levels of scavenger receptor class B, member 2 (SCARB2 (show SCARB2 Antibodies)), also known as lysosomal integral membrane protein 2 (LIMP-2 (show SCARB2 Antibodies)), and exogenous recombinant GBA1 interfered with enterovirus 71 to interact with SCARB2 (show SCARB2 Antibodies) outside the cell.

  2. identified the significant associations of the GBA L444P mutation and DYRK1A (show DYRK1A Antibodies) rs8126696 T allele with the earlier age at onset (AAO) in Parkinson's disease (PD) patients, and the A allele at MS4A6A (show MS4A6A Antibodies) rs610932 with the delayed AAO of PD.

  3. Results suggest that GBA1 mutations confer greater risk of neuropsychiatric morbidity in Parkinson disease, and that sex may affect this association

  4. Although a common ancestry among Southern Italian and Swedish Norrbottnian GD patients could not be investigated, the beta glucosidase genotype [L444P]+[L444P] is the most frequently encountered in Southern Italy

  5. Mutations in the GBA gene pathogenic for neuropathic GD and complex alleles shift longitudinal cognitive decline in PD into "high gear."

  6. In the clinical continuum between PD and DLB, patients with GBA mutations seem to localize midway, with carriers of severe mutations closer to DLB than to idiopathic PD.

  7. GBA variants predict a more rapid progression of cognitive dysfunction and motor symptoms in patients with Parkinson's.

  8. Mutations in the GBA gene were associated with more severe motor and cognitive dysfunction, supporting a specific contribution of the GBA gene or lysosome function in Lewy body disease among Ashkenazi Jews.

  9. GBA enzyme activity in Parkinson disease patients was lower in GBA mutation carriers vs. non-GBA carriers.

  10. Combination of chemo drug with beta-glucosidase 1 inhibitor sensitized hepatocellular carcinoma (HCC (show FAM126A Antibodies)) cells to chemotherapy. Our data support b-glucosidase 1 (show MOGS Antibodies) as a HCC (show FAM126A Antibodies) biomarker due to its prognosis significance

Mouse (Murine) Glucosidase, Beta, Acid (GBA) interaction partners

  1. In LIMP-2 (show SCARB2 Antibodies)-deficient brains a significant reduction in GC activity led to lipid storage, disturbed autophagic/lysosomal function, and alpha-synuclein (show SNCA Antibodies) accumulation.

  2. heterozygosity for a Gaucher disease-associated mutation in glucocerebrosidase interferes with alpha-synuclein (show SNCA Antibodies) degradation and contributes to its accumulation

  3. Data indicate that ABC transporter A family member 12 knockout (Abca12 (show ABCA12 Antibodies)(-/-)) epidermis had 5-fold more beta-glucocerebrosidase (GCase) protein, and a 5-fold increase in GCase activity.

  4. These results demonstrate, for the first time, a novel function of GBA1 as a beta (show SUCLA2 Antibodies)-ChlGlc-synthesizing enzyme.

  5. Substrate compositional variation with tissue/region and Gba1 mutations in mouse models--implications for Gaucher disease.

  6. GBA1 and GBA2 (show GBA2 Antibodies) activities had characteristic differences between the studied fibroblast, liver and brain samples.

  7. results not only point to a fundamental role for GBA in immune regulation but also suggest that GBA mutations in GD may cause widespread immune dysregulation through the accumulation of substrates

  8. This study suggested that several leads connecting GBA1 mutations with alpha-synuclein (show SNCA Antibodies) misprocessing have emerged as potential targets for the treatment of GBA1-related synucleinopathies.

  9. IFG (show IFNG Antibodies) stabilizes GCase in tissues and serum and can reduce visceral substrates in vivo.

  10. Mutations in GBA1 can cause Parkinson disease-like alpha-synuclein (show SNCA Antibodies) pathology; rescuing brain glucocerebrosidase activity might represent a therapeutic strategy for GBA1-associated synucleinopathies.

Pig (Porcine) Glucosidase, Beta, Acid (GBA) interaction partners

  1. genetic analysis and mapping of the porcine glucocerebrosidase (GBA) gene

GBA Antigen Profile

Antigen Summary

This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with GBA

  • glucosidase, beta, acid (Gba) antibody
  • glucosidase, beta, acid (GBA) antibody
  • beta glucosidase 25 (BGLU25) antibody
  • beta-glucosidase (PSPTO_3318) antibody
  • beta-glucosidase (bglX) antibody
  • beta-glucosidase (bglH-2) antibody
  • beta-glucosidase (bglX-1) antibody
  • beta-glucosidase (bglX-2) antibody
  • beta-glucosidase (bglA.2) antibody
  • bglX-2 (bglX-2) antibody
  • Beta-glucosidase (bglA4) antibody
  • BETA-GLUCOSIDASE antibody
  • betaGC antibody
  • beta glucosidase 25 antibody
  • GBA1 antibody
  • GC antibody
  • GCase antibody
  • GCB antibody
  • GLUC antibody
  • PSPTO3318 antibody
  • PSPTO4290 antibody
  • T12J13.8 antibody
  • T12J13_8 antibody

Protein level used designations for GBA

glucocerebrosidase , glucosidase, beta, acid , glucosylceramidase-like , beta-glucosidase , Beta-glucosidase , D-glucosyl-N-acylsphingosine glucohydrolase , acid beta-glucosidase , alglucerase , beta-glucocerebrosidase , glucosylceramidase , imiglucerase , lysosomal glucocerebrosidase , acid beta glucosidase , glucosidase, beta; acid (includes glucosylceramidase) , glucosidase, beta; acid

GENE ID SPECIES
684536 Rattus norvegicus
100399524 Callithrix jacchus
821201 Arabidopsis thaliana
1184976 Pseudomonas syringae pv. tomato str. DC3000
1185971 Pseudomonas syringae pv. tomato str. DC3000
2797087 Listeria monocytogenes serotype 4b str. F2365
2799486 Listeria monocytogenes serotype 4b str. F2365
2799824 Listeria monocytogenes serotype 4b str. F2365
3573796 Streptococcus pyogenes MGAS6180
4464997 Listeria welshimeri serovar 6b str. SLCC5334
5812753 Sorangium cellulosum So ce56
8955533 Sphingobium japonicum UT26S
2629 Homo sapiens
14466 Mus musculus
537087 Bos taurus
449572 Sus scrofa
100174563 Pongo abelii
449571 Pan troglodytes
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