Browse our GBA (GBA) ELISA Kits

Full name:
Glucosidase, Beta, Acid ELISA Kits (GBA)
On www.antibodies-online.com are 20 Glucosidase, Beta, Acid (GBA) ELISA Kits from 7 different suppliers available. Additionally we are shipping GBA Antibodies (86) and GBA Proteins (30) and many more products for this protein. A total of 143 GBA products are currently listed.
Synonyms:
BETA-GLUCOSIDASE, betaGC, beta glucosidase 25, GBA1, GC, GCase, GCB, GLUC, PSPTO3318, PSPTO4290, T12J13.8, T12J13_8
list all ELISA KIts Gene Name GeneID UniProt
Rat GBA GBA 684536  
GBA 2629 P04062
GBA 14466 P17439

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More ELISA Kits for GBA Interaction Partners

Arabidopsis thaliana Glucosidase, Beta, Acid (GBA) interaction partners

  1. Results describe the characterization of a beta-glucosidase homolog from Arabidopsis thaliana.

Human Glucosidase, Beta, Acid (GBA) interaction partners

  1. Local lysosomal conditions may be even more critical for some mutant lysosomal hydrolases, e.g. for mutant GBA1 . In Niemann-Pick disease type C disease, characterized by the cholesterol primary storage, GlcCer secondary accumulation could be triggered by SM secondary accumulation.

  2. the GBA1 gene, its role in Gaucher disease, and its link with Parkinson disease (Review)

  3. the decrease in enzymatic activity of lysosomal hydrolases in GBA mutation carriers may contribute to Parkinson disease pathogenesis by increasing the level of neurotoxic oligomeric alpha-synuclein (show SNCA ELISA Kits) species.

  4. the important contribution of GBA (L444P and N370S) mutations to parkinsonism in Brazilian families.

  5. In a Flanders-Belgian cohort, carrier status of a heterozygous glucocerebrosidase (GBA) mutation was a strong genetic risk factor for Parkinson's disease (PD). The GBA mutation frequency of 4.5% is comparable to previously reported data in other European PD patient cohorts.

  6. Rab7 (show RAB7B ELISA Kits) accumulated in GCase deficient cells, supporting the notion that lysosomal recycling is impaired. Since recombinant GCase can reverse ALR (show GFER ELISA Kits) impairment, we anticipate that strategies to restore GCase activity in the brains of both sporadic patients with PD and those with GBA1 mutations will improve autophagy lysosomal pathway, preventing the accumulation of a-synuclein and spread of pathology.

  7. course of motor and non-motor symptoms as well as treatment-related motor complications could be influenced by GBA variants

  8. The anti-enterovirus 71 activity of GBA1 was bimodal: endogenous GBA1 restricted cell surface expression levels of scavenger receptor class B, member 2 (SCARB2 (show SCARB2 ELISA Kits)), also known as lysosomal integral membrane protein 2 (LIMP-2 (show SCARB2 ELISA Kits)), and exogenous recombinant GBA1 interfered with enterovirus 71 to interact with SCARB2 (show SCARB2 ELISA Kits) outside the cell.

  9. identified the significant associations of the GBA L444P mutation and DYRK1A rs8126696 T allele with the earlier age at onset (AAO) in Parkinson's disease (PD) patients, and the A allele at MS4A6A rs610932 with the delayed AAO of PD.

  10. Results suggest that GBA1 mutations confer greater risk of neuropsychiatric morbidity in Parkinson disease, and that sex may affect this association

Mouse (Murine) Glucosidase, Beta, Acid (GBA) interaction partners

  1. Rab7 (show RAB7A ELISA Kits) accumulated in GCase deficient cells, supporting the notion that lysosomal recycling is impaired. Since recombinant GCase can reverse ALR (show GFER ELISA Kits) impairment, we anticipate that strategies to restore GCase activity in the brains of both sporadic patients with PD and those with GBA1 mutations will improve autophagy lysosomal pathway, preventing the accumulation of a-synuclein and spread of pathology.

  2. In LIMP-2 (show SCARB2 ELISA Kits)-deficient brains a significant reduction in GC activity led to lipid storage, disturbed autophagic/lysosomal function, and alpha-synuclein (show SNCA ELISA Kits) accumulation.

  3. heterozygosity for a Gaucher disease-associated mutation in glucocerebrosidase interferes with alpha-synuclein (show SNCA ELISA Kits) degradation and contributes to its accumulation

  4. Data indicate that ABC transporter A family member 12 knockout (Abca12 (show ABCA12 ELISA Kits)(-/-)) epidermis had 5-fold more beta-glucocerebrosidase (GCase) protein, and a 5-fold increase in GCase activity.

  5. These results demonstrate, for the first time, a novel function of GBA1 as a beta (show SUCLA2 ELISA Kits)-ChlGlc-synthesizing enzyme.

  6. Substrate compositional variation with tissue/region and Gba1 mutations in mouse models--implications for Gaucher disease.

  7. GBA1 and GBA2 (show GBA2 ELISA Kits) activities had characteristic differences between the studied fibroblast, liver and brain samples.

  8. results not only point to a fundamental role for GBA in immune regulation but also suggest that GBA mutations in GD may cause widespread immune dysregulation through the accumulation of substrates

  9. This study suggested that several leads connecting GBA1 mutations with alpha-synuclein (show SNCA ELISA Kits) misprocessing have emerged as potential targets for the treatment of GBA1-related synucleinopathies.

  10. IFG (show IFNG ELISA Kits) stabilizes GCase in tissues and serum and can reduce visceral substrates in vivo.

Pig (Porcine) Glucosidase, Beta, Acid (GBA) interaction partners

  1. genetic analysis and mapping of the porcine glucocerebrosidase (GBA) gene

GBA Antigen Profile

Antigen Summary

This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with GBA

  • glucosidase, beta, acid (Gba) Elisa Kit
  • glucosidase, beta, acid (GBA) Elisa Kit
  • beta glucosidase 25 (BGLU25) Elisa Kit
  • beta-glucosidase (PSPTO_3318) Elisa Kit
  • beta-glucosidase (bglX) Elisa Kit
  • beta-glucosidase (bglH-2) Elisa Kit
  • beta-glucosidase (bglX-1) Elisa Kit
  • beta-glucosidase (bglX-2) Elisa Kit
  • beta-glucosidase (bglA.2) Elisa Kit
  • bglX-2 (bglX-2) Elisa Kit
  • Beta-glucosidase (bglA4) Elisa Kit
  • BETA-GLUCOSIDASE Elisa Kit
  • betaGC Elisa Kit
  • beta glucosidase 25 Elisa Kit
  • GBA1 Elisa Kit
  • GC Elisa Kit
  • GCase Elisa Kit
  • GCB Elisa Kit
  • GLUC Elisa Kit
  • PSPTO3318 Elisa Kit
  • PSPTO4290 Elisa Kit
  • T12J13.8 Elisa Kit
  • T12J13_8 Elisa Kit

Protein level used designations for GBA

glucocerebrosidase , glucosidase, beta, acid , glucosylceramidase-like , beta-glucosidase , Beta-glucosidase , D-glucosyl-N-acylsphingosine glucohydrolase , acid beta-glucosidase , alglucerase , beta-glucocerebrosidase , glucosylceramidase , imiglucerase , lysosomal glucocerebrosidase , acid beta glucosidase , glucosidase, beta; acid (includes glucosylceramidase) , glucosidase, beta; acid

GENE ID SPECIES
684536 Rattus norvegicus
100399524 Callithrix jacchus
821201 Arabidopsis thaliana
1184976 Pseudomonas syringae pv. tomato str. DC3000
1185971 Pseudomonas syringae pv. tomato str. DC3000
2797087 Listeria monocytogenes serotype 4b str. F2365
2799486 Listeria monocytogenes serotype 4b str. F2365
2799824 Listeria monocytogenes serotype 4b str. F2365
3573796 Streptococcus pyogenes MGAS6180
4464997 Listeria welshimeri serovar 6b str. SLCC5334
5812753 Sorangium cellulosum So ce56
8955533 Sphingobium japonicum UT26S
2629 Homo sapiens
14466 Mus musculus
537087 Bos taurus
449572 Sus scrofa
100174563 Pongo abelii
449571 Pan troglodytes
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