Browse our anti-FCGR2B (FCGR2B) Antibodies

Full name:
anti-Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) Antibodies (FCGR2B)
On www.antibodies-online.com are 88 Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B) Antibodies from 19 different suppliers available. Additionally we are shipping FCGR2B Proteins (24) and FCGR2B Kits (19) and many more products for this protein. A total of 150 FCGR2B products are currently listed.
Synonyms:
AI528646, CD32, CD32B, F630109E10Rik, FCG2, Fcgr2, Fcgr2a, FCGR2B, FcgRII, Fcr-2, Fcr-3, Fc[g]RII, IGFR2, Ly-17, Ly-m20, Lym-1
list all antibodies Gene Name GeneID UniProt
FCGR2B 2213 P31994
FCGR2B 14130 P08101
FCGR2B    

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anti-Human FCGR2B Antibodies:

anti-Mouse (Murine) FCGR2B Antibodies:

anti-Rat (Rattus) FCGR2B Antibodies:

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Top referenced anti-FCGR2B Antibodies

  1. Human Polyclonal FCGR2B Primary Antibody for WB - ABIN657908 : Prokopec, Rhodiner, Matt, Lindqvist, Kleinau: Down regulation of Fc and complement receptors on B cells in rheumatoid arthritis. in Clinical immunology (Orlando, Fla.) 2010 (PubMed)
    Show all 4 references for 657908

  2. Human Polyclonal FCGR2B Primary Antibody for IHC, ELISA - ABIN185377 : McGaha, Sorrentino, Ravetch: Restoration of tolerance in lupus by targeted inhibitory receptor expression. in Science (New York, N.Y.) 2005 (PubMed)
    Show all 2 references for 185377

  3. Human Polyclonal FCGR2B Primary Antibody for IHC (p), WB - ABIN515564 : Smith, Wietgrefe, Shang, Reilly, Southern, Perkey, Duan, Kohler, Müller, Robinson, Carlis, Li, Johnson, Haase: Live simian immunodeficiency virus vaccine correlate of protection: immune complex-inhibitory Fc receptor interactions that reduce target cell availability. in Journal of immunology (Baltimore, Md. : 1950) 2014 (PubMed)

More Antibodies against FCGR2B Interaction Partners

Human Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B) interaction partners

  1. results indicate that FcgammaRIIB is not uniquely able to promote membrane recruitment of SHIP, but rather modulates its function via formation of distinct signaling complexes. Membrane recruitment of SHIP via Syk (show SYK Antibodies)-dependent mechanisms may be an important factor modulating immunoreceptor signaling.

  2. Fc gamma receptor IIb was significantly elevated in abdominal aortic aneurysm (AAA (show APP Antibodies)) tissues compared to normal aortas. Fc gamma receptor IIb may be involved in the pathogenesis of AAA (show APP Antibodies) by regulation of inflammatory reactions.

  3. Fc-gamma receptor (show FCGR1A Antibodies) polymorphisms differentially influence susceptibility to systemic lupus erythematosus and lupus nephritis.

  4. LPS (show IRF6 Antibodies) activation of TLR4 (show TLR4 Antibodies) significantly increased MARCH3 (show MARCH3 Antibodies) expression and that siRNA against MARCH3 (show MARCH3 Antibodies) prevented the decrease in FcgammaRIIb following LPS (show IRF6 Antibodies) treatment.

  5. a rare FCGR2B null-variant allele was found, in which a polymorphic stop codon of FCGR2C is introduced into one FCGR2B gene

  6. FcgammaRIIB requires Btk (show BTK Antibodies) and p38 MAPK (show MAPK14 Antibodies) to mediate antigen-independent inhibition in human B cells.

  7. The FCGR2B variant leads to reduced serum IL-6 (show IL6 Antibodies), later disease onset and reduced need for biological treatment, but does not seem to aggravate RA. The TM region variant is associated with a lower activation state of the Tregs and naive and memory B cells.

  8. FcgIIb on GM-CSF (show CSF2 Antibodies) macrophages has a role in controlling immune complex-mediated inhibition of inflammatory signals

  9. none of the three functional polymorphisms in FcgammaR genes explored here, the FCGR3A (show CD16 Antibodies) F158V and FCGR2B I232T nsSNPs and the VNTR in FCGRT (show FCGRT Antibodies), showed an association with the response to TNFi in patients with rheumatoid arthritis

  10. Data show that the recombinant Fc gamma receptors FcgammaRIa (show FCGR1A Antibodies), FcgammaRIIa, FcgammaRIIb, FcgammaRIIIa(Phe158/Val158), and FcgammaRIIIb glycosylation is complex and varied between receptors.

Mouse (Murine) Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B) interaction partners

  1. This study reports the creation of a mouse model of autoimmunity-associated atherosclerosis by transplanting bone marrow from FcgammaRIIB knockout (FcRIIB(-/-)) mice into LDL receptor (show LDLR Antibodies) knockout mice.

  2. These results reveal a novel and unexpected function of hepatic Fc-gamma-RIIB in the targeted downregulation of GPVI (show GP6 Antibodies) in vivo.

  3. Cytokine release was quantified from FVIII (show F8 Antibodies)(-/-) splenocytes restimulated with FVIII (show F8 Antibodies) in the absence or presence of different anti-FcgammaRIIB (CD32) Antibodies (anti-CD32 mAbs) over 6 days.

  4. Collectively these findings reveal that by inhibiting eNOS (show NOS3 Antibodies), endothelial FcgammaRIIB activation by CRP (show CRP Antibodies) blunts insulin (show INS Antibodies) delivery to skeletal muscle to cause insulin (show INS Antibodies) resistance.

  5. Macrophages' activating FcgammaR expression profile are associated with the development of ITP (show ITPA Antibodies) in Treg-deficient mice.

  6. this study shows that FcgammaRIIb drives the sequential dephosphorylation system comprising SHIP1 (show INPP5D Antibodies)/2 and Inpp4a (show INPP4A Antibodies), and accelerates phagosome acidification

  7. CD32 is a crucial regulator of FVIII (show F8 Antibodies)-specific B cells and is required for the differentiation of memory B cells into antibody-secreting cells.

  8. Aggregated alpha-Synuclein (alpha-syn) inhibited microglial phagocytosis. The inhibitory effect of aggregated alpha-syn on microglial phagocytosis was due to the activation of SHP-1 and FcgammaRIIB on microglia.

  9. Fcgr2b(-/-) mice lose bone upon the onset of a hypergammaglobulinemia or the administration of IgG1 immune complexes.

  10. IgG (FcgammaR) IIb is involved in the suppressive effect of immune complex on TLR9 (show TLR9 Antibodies)-mediated CD40 (show CD40 Antibodies), CD80 (show CD80 Antibodies) and IL-6 (show IL6 Antibodies) expression.

FCGR2B Antigen Profile

Antigen Summary

The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with FCGR2B

  • Fc fragment of IgG, low affinity IIb, receptor (CD32) (FCGR2B) antibody
  • Fc receptor, IgG, low affinity IIb (Fcgr2b) antibody
  • AI528646 antibody
  • CD32 antibody
  • CD32B antibody
  • F630109E10Rik antibody
  • FCG2 antibody
  • Fcgr2 antibody
  • Fcgr2a antibody
  • FCGR2B antibody
  • FcgRII antibody
  • Fcr-2 antibody
  • Fcr-3 antibody
  • Fc[g]RII antibody
  • IGFR2 antibody
  • Ly-17 antibody
  • Ly-m20 antibody
  • Lym-1 antibody

Protein level used designations for FCGR2B

CDw32 , Fc fragment of IgG, low affinity II, receptor for (CD32) , Fc fragment of IgG, low affinity IIb, receptor for (CD32) , Fc gamma RIIb , fc-gamma RII-b , fc-gamma-RIIb , fcRII-b , igG Fc receptor II-b , low affinity immunoglobulin gamma Fc region receptor II-b , Fc fragment of IgG, low affinity IIb, receptor (CD32) , Fc fragment of IgG, low affinity IIb, receptor , IgG Fc gamma receptor II , Fc gamma RIIB , Fc-gamma-RII , FcgammaRIIB , fc gamma receptor IIB , fc-gamma RII , fc-gamma-RIIB , fcRII , igG Fc receptor II beta , low affinity immunoglobulin gamma Fc region receptor II , lymphocyte antigen 17

GENE ID SPECIES
2213 Homo sapiens
746456 Pan troglodytes
100192432 Ovis aries
14130 Mus musculus
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