FCGR2B antibody (AA 1-310)

Catalog No. ABIN515564

There is 1 publication for this product available. The Mouse Polyclonal anti-FCGR2B antibody is suitable to detect FCGR2B in samples from Human. It has been validated for WB and IHC (p).

Quick Overview for FCGR2B antibody (AA 1-310) (ABIN515564)

Target: FCGR2B (Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B))

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This FCGR2B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-FCGR2B Antibody

Binding Specificity: AA 1-310

Purpose: Mouse polyclonal antibody raised against a full-length human FCGR2B protein.

Sequence: MGILSFLPVL ATESDWADCK SPQPWGHMLL WTAVLFLAPV AGTPAAPPKA VLKLEPQWIN VLQEDSVTLT CRGTHSPESD SIQWFHNGNL IPTHTQPSYR FKANNNDSGE YTCQTGQTSL SDPVHLTVLS EWLVLQTPHL EFQEGETIVL RCHSWKDKPL VKVTFFQNGK SKKFSRSDPN FSIPQANHSH SGDYHCTGNI GYTLYSSKPV TITVQAPSSS PMGIIVAVVT GIAVAAIVAA VVALIYCRKK RISALPGYPE CREMGETLPE KPANPTNPDE ADKVGAENTI TYSLLMHPDA LEEPDDQNRI

Cross-Reactivity: Human

Characteristics: Antibody reactive against mammalian transfected lysate.

Immunogen: FCGR2B (NP_003992.3, 1 a.a. ~ 310 a.a) full-length human protein.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-FCGR2B antibody (ABIN515564)

Smith, Wietgrefe, Shang, Reilly, Southern, Perkey, Duan, Kohler, Müller, Robinson, Carlis, Li, Johnson, Haase: "Live simian immunodeficiency virus vaccine correlate of protection: immune complex-inhibitory Fc receptor interactions that reduce target cell availability." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 193, Issue 6, pp. 3126-33, (2014) (PubMed).

Target Details for FCGR2B

Target: FCGR2B (Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B))

Alternative Name: FCGR2B

Background: Full Gene Name: Fc fragment of IgG, low affinity IIb, receptor (CD32)
Synonyms: CD32,CD32B,FCG2,FCGR2,IGFR2

Gene ID: 2213

NCBI Accession: NM_004001

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, BCR Signaling