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Browse our anti-NLRP3 (NLRP3) Antibodies

Full name:
anti-NLR Family, Pyrin Domain Containing 3 Antibodies (NLRP3)
On are 205 NLR Family, Pyrin Domain Containing 3 (NLRP3) Antibodies from 27 different suppliers available. Additionally we are shipping NLRP3 Kits (8) and NLRP3 Proteins (4) and many more products for this protein. A total of 230 NLRP3 products are currently listed.
AGTAVPRL, AII, AII/AVP, AVP, C1orf7, Cias1, CLR1.1, FCAS, FCU, Mmig1, MWS, NALP3, Pypaf1
list all antibodies Gene Name GeneID UniProt
NLRP3 114548 Q96P20
NLRP3 216799 Q8R4B8
NLRP3 287362  

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Top referenced anti-NLRP3 Antibodies

  1. Human Monoclonal NLRP3 Primary Antibody for FACS, ICC - ABIN4898963 : Hu, Zhang, Wang, Mao, Lv, Yuan, Huang, Ding, Xie, Liu: Knockout of Ccr2 alleviates photoreceptor cell death in rodent retina exposed to chronic blue light. in Cell death & disease 2016 (PubMed)
    Show all 6 references for ABIN4898963

  2. Human Polyclonal NLRP3 Primary Antibody for IHC, IHC (p) - ABIN4340115 : Abdul-Sater, Koo, Häcker, Ojcius: Inflammasome-dependent caspase-1 activation in cervical epithelial cells stimulates growth of the intracellular pathogen Chlamydia trachomatis. in The Journal of biological chemistry 2009 (PubMed)
    Show all 5 references for ABIN4340115

  3. Human Polyclonal NLRP3 Primary Antibody for IF (p), IHC (p) - ABIN1386361 : Zendedel, Johann, Mehrabi, Joghataei, Hassanzadeh, Kipp, Beyer: Activation and Regulation of NLRP3 Inflammasome by Intrathecal Application of SDF-1a in a Spinal Cord Injury Model. in Molecular neurobiology 2015 (PubMed)
    Show all 4 references for ABIN1386361

  4. Human Monoclonal NLRP3 Primary Antibody for IHC, IHC (fro) - ABIN4340117 : Shio, Tiemi Shio, Eisenbarth, Savaria, Vinet, Bellemare, Harder, Sutterwala, Bohle, Descoteaux, Flavell, Olivier: Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases. in PLoS pathogens 2009 (PubMed)
    Show all 3 references for ABIN4340117

  5. Human Polyclonal NLRP3 Primary Antibody for IHC (p), IHC - ABIN251577 : Wei, Chen, James, Stone, Chamley: IL-1 beta but not the NALP3 inflammasome is an important determinant of endothelial cell responses to necrotic/dangerous trophoblastic debris. in Placenta 2015 (PubMed)
    Show all 2 references for ABIN251577

  6. Human Polyclonal NLRP3 Primary Antibody for IHC (p), WB - ABIN652504 : Jhang, Lu, Ho, Cheng, Yen: Protective Effects of Catechin against Monosodium Urate-Induced Inflammation through the Modulation of NLRP3 Inflammasome Activation. in Journal of agricultural and food chemistry 2015 (PubMed)
    Show all 2 references for ABIN652504

  7. Human Polyclonal NLRP3 Primary Antibody for EIA, WB - ABIN453768 : Feldmann, Prieur, Quartier, Berquin, Certain, Cortis, Teillac-Hamel, Fischer, de Saint Basile: Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes. in American journal of human genetics 2002 (PubMed)

  8. Human Polyclonal NLRP3 Primary Antibody for IHC, ELISA - ABIN185676 : Kanneganti, Ozören, Body-Malapel, Amer, Park, Franchi, Whitfield, Barchet, Colonna, Vandenabeele, Bertin, Coyle, Grant, Akira, Núñez: Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3. in Nature 2006 (PubMed)

  9. Human Polyclonal NLRP3 Primary Antibody for ELISA, WB - ABIN184887 : Hoffman, Mueller, Broide, Wanderer, Kolodner: Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome. in Nature genetics 2001 (PubMed)

More Antibodies against NLRP3 Interaction Partners

Human NLR Family, Pyrin Domain Containing 3 (NLRP3) interaction partners

  1. Collectively, our novel findings demonstrate that Ro5-4864 effectively inhibited ATP-induced NLRP3 inflammasome activation through the prevention of mitochondrial perturbation. Our results indicate Ro5-4864 as a promising candidate for the treatment of NLRP3 inflammasome-related diseases.

  2. N. fowleri infection induces the NLRP3 inflammasome.

  3. Study demonstrates that the expression of the NLRP3-caspase-1 (show CASP1 Antibodies)-IL-18 (show IL18 Antibodies) axis is highly expressed in the peripheral blood mononuclear cells of patients with bullous pemphigoid (show DST Antibodies) (BP), and correlated with disease activity, suggesting its involvement in the pathogenesis and progression of BP.

  4. One of the key results of this study is that the induction of NLRP3 expression by Lipopolysaccharide is inhibited in the presence of IL-4 (show IL4 Antibodies)+IL-13 (show IL13 Antibodies) (M2 phenotype) at both mRNA and protein level in monocytes and macrophages.

  5. The objective of this review is to integrate the findings linking mitochondrial integrity to the activation of the NLRP3 inflammasome and to evaluate how caloric restriction or caloric restriction mimetic compounds may play a role in attenuating the NLRP3 inflammasome and sterile inflammation. [review]

  6. There is a positive correlation of NLRP3 level with severity of coronary atherosclerosis. NLRP3 showed good predictive value for major adverse cardiac events.

  7. NLRP3 inflammasome signaling pathway played a pro-inflammatory role in the pathogenesis of human chronic rhinosinusitis with nasal polyps , especially in Eosinophilic CRSwNP

  8. Lipopolysaccharide activates the reactive oxygen spieces -dependent NLRP3 inflammasome.

  9. NLRP3 inflammasome activation can lead to NAFLD (show TSC2 Antibodies) development and progression, including hepatic steatosis, inflammation, liver injury, and fibrogenesis. NLRP3 inflammasome may serve as a novel therapeutic target for the treatment of Nonalcoholic fatty liver disease and Nonalcoholic steatohepatitis.

  10. The mutation c.92A>T in exon 1 of the NLRP3 gene is a novel mutation associated with Muckle-Wells Syndrome.

Mouse (Murine) NLR Family, Pyrin Domain Containing 3 (NLRP3) interaction partners

  1. this study shows that alum is able to NLRP3 inflammasome in murine basophils in the same way as alum in professional antigen-presenting cells, but NLRP3 is not required for Th2-promoting activities on basophils by alum

  2. NLRP3 inflammasome levels are regulated by OGG1 (show OGG1 Antibodies)-dependent DNA repair which plays a protective role in atherogenesis.

  3. TNF-alpha (show TNF Antibodies) induces caspase-1 (show CASP1 Antibodies) activation in an inflammasome-independent manner in 3T3-L1 cells and that the ERK (show EPHB2 Antibodies)-dependent expression of NLRP3 may play a role independently of its canonical role as a component of inflammasomes.

  4. NLRP3 inflammasome and local IL-1beta((+))F4/80((+))Ly6C((+)) inflammatory macrophages contribute to pathogenesis of VCP-associated myopathy

  5. this study shows that genipin protects against acute lung injury through inhibiting NLRP3 signaling pathway

  6. this study shows that neuroprotective effect of sinomenine against ischemic stroke is mediated via suppression of NLRP3 inflammasome

  7. this study shows that the protective effect of rhapontin is from blocking the NLRP3 priming cascade reaction and is dependent on SIRT1 (show SIRT1 Antibodies) activation

  8. this study shows that LPS (show TLR4 Antibodies)-induced mastitis can be abated by mangiferin through inhibiting NLRP3 signaling pathway

  9. telmisartan can reduce traumatic cerebral edema by inhibiting the NLRP3 inflammasome-regulated IL-1beta (show IL1B Antibodies) and IL-18 (show IL18 Antibodies) accumulation.

  10. this study shows that biochanin A protects acute liver injury by inhibiting NLRP3 inflammasome activation

NLRP3 Antigen Profile

Antigen Summary

This gene encodes a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling, and it plays a role in the regulation of inflammation, the immune response, and apoptosis. Mutations in this gene are associated with familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS), chronic infantile neurological cutaneous and articular (CINCA) syndrome, and neonatal-onset multisystem inflammatory disease (NOMID). Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Alternative 5' UTR structures are suggested by available data\; however, insufficient evidence is available to determine if all of the represented 5' UTR splice patterns are biologically valid.

Alternative names and synonyms associated with NLRP3

  • NLR family, pyrin domain containing 3 (NLRP3) antibody
  • NLR family, pyrin domain containing 3 (LOC100351623) antibody
  • NLR family, pyrin domain containing 3 (nlrp3) antibody
  • NLR family, pyrin domain containing 3 (Nlrp3) antibody
  • AGTAVPRL antibody
  • AII antibody
  • AII/AVP antibody
  • AVP antibody
  • C1orf7 antibody
  • Cias1 antibody
  • CLR1.1 antibody
  • FCAS antibody
  • FCU antibody
  • Mmig1 antibody
  • MWS antibody
  • NALP3 antibody
  • Pypaf1 antibody

Protein level used designations for NLRP3

NACHT, LRR and PYD domains-containing protein 3 , cold autoinflammatory syndrome 1 , cryopyrin , NLR family, pyrin domain containing 3 , NACHT, LRR and PYD domains-containing protein 3-like , NACHT domain-, leucine-rich repeat-, and PYD-containing protein 3 , NACHT, LRR and PYD containing protein 3 , PYRIN-containing APAF1-like protein 1 , caterpiller protein 1.1 , cold autoinflammatory syndrome 1 protein , nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 3 , NACHT/LRR/pyrin domain-containing protein 3 , cold autoinflammatory syndrome 1 homolog , cold autoinflammatory syndrome 1 protein homolog , mast cell maturation inducible protein 1 , mast cell maturation-associated-inducible protein 1 , NLR family pyrin domain containing 3

423021 Gallus gallus
469743 Pan troglodytes
490576 Canis lupus familiaris
100351623 Oryctolagus cuniculus
100381165 Xenopus laevis
100392399 Callithrix jacchus
114548 Homo sapiens
216799 Mus musculus
538639 Bos taurus
287362 Rattus norvegicus
701278 Macaca mulatta
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