Browse our anti-NLRP3 (NLRP3) Antibodies

Full name:
anti-NLR Family, Pyrin Domain Containing 3 Antibodies (NLRP3)
On www.antibodies-online.com are 222 NLR Family, Pyrin Domain Containing 3 (NLRP3) Antibodies from 27 different suppliers available. Additionally we are shipping NLRP3 Kits (11) and NLRP3 Proteins (4) and many more products for this protein. A total of 251 NLRP3 products are currently listed.
Synonyms:
AGTAVPRL, AII, AII/AVP, AVP, C1orf7, Cias1, CLR1.1, FCAS, FCU, Mmig1, MWS, NALP3, Pypaf1
list all antibodies Gene Name GeneID UniProt
NLRP3 114548 Q96P20
NLRP3 216799 Q8R4B8
NLRP3 287362  

Show all species

Show all synonyms

Most Popular Reactivities for anti-NLRP3 (NLRP3) Antibodies

Select your species and application

anti-Human NLRP3 Antibodies:

anti-Mouse (Murine) NLRP3 Antibodies:

anti-Rat (Rattus) NLRP3 Antibodies:

All available anti-NLRP3 Antibodies

Go to our pre-filtered search.

Top referenced anti-NLRP3 Antibodies

  1. Human Polyclonal NLRP3 Primary Antibody for IF (p), IHC (p) - ABIN1386361 : Zendedel, Johann, Mehrabi, Joghataei, Hassanzadeh, Kipp, Beyer: Activation and Regulation of NLRP3 Inflammasome by Intrathecal Application of SDF-1a in a Spinal Cord Injury Model. in Molecular neurobiology 2015 (PubMed)
    Show all 7 references for 1386361

  2. Human Monoclonal NLRP3 Primary Antibody for FACS, ICC - ABIN4898963 : Hu, Zhang, Wang, Mao, Lv, Yuan, Huang, Ding, Xie, Liu: Knockout of Ccr2 alleviates photoreceptor cell death in rodent retina exposed to chronic blue light. in Cell death & disease 2016 (PubMed)
    Show all 6 references for 4898963

  3. Human Polyclonal NLRP3 Primary Antibody for IHC (p), WB - ABIN652504 : Jhang, Lu, Ho, Cheng, Yen: Protective Effects of Catechin against Monosodium Urate-Induced Inflammation through the Modulation of NLRP3 Inflammasome Activation. in Journal of agricultural and food chemistry 2015 (PubMed)
    Show all 2 references for 652504

  4. Human Polyclonal NLRP3 Primary Antibody for WB - ABIN3043571 : Xue, Wang, Du, Zhu: Maternal obesity induces gut inflammation and impairs gut epithelial barrier function in nonobese diabetic mice. in The Journal of nutritional biochemistry 2014 (PubMed)
    Show all 2 references for 3043571

  5. Human Polyclonal NLRP3 Primary Antibody for IHC (p), IHC - ABIN251577 : Wei, Chen, James, Stone, Chamley: IL-1 beta but not the NALP3 inflammasome is an important determinant of endothelial cell responses to necrotic/dangerous trophoblastic debris. in Placenta 2015 (PubMed)
    Show all 2 references for 251577

  6. Human Polyclonal NLRP3 Primary Antibody for ELISA, IHC (p) - ABIN249728 : Hoffman, Mueller, Broide, Wanderer, Kolodner: Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome. in Nature genetics 2001 (PubMed)

  7. Human Polyclonal NLRP3 Primary Antibody for IHC, ELISA - ABIN185676 : Kanneganti, Ozören, Body-Malapel, Amer, Park, Franchi, Whitfield, Barchet, Colonna, Vandenabeele, Bertin, Coyle, Grant, Akira, Núñez: Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3. in Nature 2006 (PubMed)

  8. Human Monoclonal NLRP3 Primary Antibody for WB - ABIN4340119 : Dolunay, Senol, Temiz-Resitoglu, Guden, Sari, Sahan-Firat, Tunctan: Inhibition of NLRP3 Inflammasome Prevents LPS-Induced Inflammatory Hyperalgesia in Mice: Contribution of NF-κB, Caspase-1/11, ASC, NOX, and NOS Isoforms. in Inflammation 2016 (PubMed)

  9. Human Polyclonal NLRP3 Primary Antibody for EIA, WB - ABIN453768 : Feldmann, Prieur, Quartier, Berquin, Certain, Cortis, Teillac-Hamel, Fischer, de Saint Basile: Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes. in American journal of human genetics 2002 (PubMed)

More Antibodies against NLRP3 Interaction Partners

Human NLR Family, Pyrin Domain Containing 3 (NLRP3) interaction partners

  1. defective ribosomal products in blebs induced IL-1beta (show IL1B Antibodies) release from peripheral blood mononuclear cells or THP-1 (show GLI2 Antibodies) cells without lipopolysaccharide priming, but required the core machinery of NLRP3 inflammasomes.

  2. besides its role in the inhibition of the NF-kappaB (show NFKB1 Antibodies) pathway, NLRC3 (show NLRC3 Antibodies) interferes with the assembly and activity of the NALP3 inflammasome complex by competing with ASC (show PYCARD Antibodies) for pro-caspase-1 (show CASP1 Antibodies) binding

  3. uropathogenic E. coli use the multifunctional virulence factor TcpC to induce NLRP3 inflammasome expression, and attenuate innate immune responses in the urinary tract

  4. miR (show MLXIP Antibodies)-223 limits intestinal inflammation by constraining the nlrp3 inflammasome.

  5. These data suggest that targeting NLRP3 holds the promise for the immunotherapy of pancreatic ductal adenocarcinoma.

  6. EAE induced by weak activation of innate immunity requires the NLRP3 inflammasome and is sensitive to interferon-beta (show IFNB1 Antibodies) treatment

  7. this is the first report describing the existence and function of the nucleotide-binding oligomerization domain-like receptor protein 3 (show HSPB3 Antibodies) inflammasome in human dendritic cells.

  8. PTPN22 (show PTPN22 Antibodies) deficiency resulted in pronounced colitis, increased NLRP3 phosphorylation, but reduced levels of mature IL-1beta (show IL1B Antibodies).

  9. The authors further demonstrated that the upregulation of sterol regulatory element-binding protein (show CNBP Antibodies) (SREBP)-1c (show SREBF1 Antibodies) by activation of the Akt (show AKT1 Antibodies) and p70S6K (show RPS6KB1 Antibodies) pathways is critical for high-glucose-treated Porphyromonas gingivalis-induced NLRP3 expression.

  10. LFG (show FAIM2 Antibodies)-500 markedly suppresses epithelial mesenchymal transformation by inhibiting the NLRP3 inflammasome in the inflammatory microenvironment.

Mouse (Murine) NLR Family, Pyrin Domain Containing 3 (NLRP3) interaction partners

  1. proposed that TLR9 (show TLR9 Antibodies) regulates the NF-kappaB (show NFKB1 Antibodies)-NLRP3-IL-1beta (show IL1B Antibodies) pathway negatively in Salmonella-induced NKG2D (show KLRK1 Antibodies)-mediated intestinal inflammation and plays a critical role in defense against S. typhimurium infection and in the protection of intestinal integrity.

  2. The results suggest that mitochondrial function is required somewhat specifically for ATP-induced NLRP3 inflammasome activation.

  3. uropathogenic E. coli use the multifunctional virulence factor TcpC to induce NLRP3 inflammasome expression, and attenuate innate immune responses in the urinary tract

  4. NLRP3(-/-) mice had reduced defects in echo/Doppler parameters in heart after cecal ligation and puncture

  5. this study shows that plant lectins can act as an exogenous "danger signal" that can activate the NLRP3 inflammasome and suggest that dietary lectins might promote inflammatory diseases via the NLRP3 inflammasome

  6. miR (show MLXIP Antibodies)-223 limits intestinal inflammation by constraining the nlrp3 inflammasome.

  7. NLRP3 is a novel target of the YopM protein.

  8. These results propose that the balance between kinases and phosphatases acting on the NLRP3 pyrin (show MEFV Antibodies) domain is critical for NLRP3 activation.

  9. These data suggest that targeting NLRP3 holds the promise for the immunotherapy of pancreatic ductal adenocarcinoma.

  10. this study shows that oxidized low-density lipoprotein immune complexes increased expression of inflammasome-related gene Nlrp3

NLRP3 Antigen Profile

Antigen Summary

This gene encodes a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling, and it plays a role in the regulation of inflammation, the immune response, and apoptosis. Mutations in this gene are associated with familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS), chronic infantile neurological cutaneous and articular (CINCA) syndrome, and neonatal-onset multisystem inflammatory disease (NOMID). Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Alternative 5' UTR structures are suggested by available data\; however, insufficient evidence is available to determine if all of the represented 5' UTR splice patterns are biologically valid.

Alternative names and synonyms associated with NLRP3

  • NLR family, pyrin domain containing 3 (NLRP3) antibody
  • NLR family, pyrin domain containing 3 (LOC100351623) antibody
  • NLR family, pyrin domain containing 3 (nlrp3) antibody
  • NLR family, pyrin domain containing 3 (Nlrp3) antibody
  • AGTAVPRL antibody
  • AII antibody
  • AII/AVP antibody
  • AVP antibody
  • C1orf7 antibody
  • Cias1 antibody
  • CLR1.1 antibody
  • FCAS antibody
  • FCU antibody
  • Mmig1 antibody
  • MWS antibody
  • NALP3 antibody
  • Pypaf1 antibody

Protein level used designations for NLRP3

NACHT, LRR and PYD domains-containing protein 3 , cold autoinflammatory syndrome 1 , cryopyrin , NLR family, pyrin domain containing 3 , NACHT, LRR and PYD domains-containing protein 3-like , NACHT domain-, leucine-rich repeat-, and PYD-containing protein 3 , NACHT, LRR and PYD containing protein 3 , PYRIN-containing APAF1-like protein 1 , caterpiller protein 1.1 , cold autoinflammatory syndrome 1 protein , nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 3 , NACHT/LRR/pyrin domain-containing protein 3 , cold autoinflammatory syndrome 1 homolog , cold autoinflammatory syndrome 1 protein homolog , mast cell maturation inducible protein 1 , mast cell maturation-associated-inducible protein 1 , NLR family pyrin domain containing 3

GENE ID SPECIES
423021 Gallus gallus
469743 Pan troglodytes
490576 Canis lupus familiaris
100351623 Oryctolagus cuniculus
100381165 Xenopus laevis
100392399 Callithrix jacchus
114548 Homo sapiens
216799 Mus musculus
538639 Bos taurus
287362 Rattus norvegicus
701278 Macaca mulatta
Selected quality suppliers for anti-NLRP3 (NLRP3) Antibodies
Did you look for something else?