Browse our Peripheral-Type Benzodiazepine Receptor (TSPO) ELISA Kits

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Peripheral-Type Benzodiazepine Receptor ELISA Kits (TSPO)
On are 25 Peripheral-Type Benzodiazepine Receptor (TSPO) ELISA Kits from 8 different suppliers available. Additionally we are shipping Peripheral-Type Benzodiazepine Receptor Antibodies (70) and Peripheral-Type Benzodiazepine Receptor Proteins (7) and many more products for this protein. A total of 113 Peripheral-Type Benzodiazepine Receptor products are currently listed.
BPBS, Bzrp, DBI, IBP, LOC732875, LOC100136652, LOC100280949, MBR, mDRC, PBR, PBS, pk18, PKBS, PTBR, Ptbzr, PTBZR02, RATPTBZR02, TSPO, Tspo1

More ELISA Kits for Peripheral-Type Benzodiazepine Receptor Interaction Partners

Mouse (Murine) Peripheral-Type Benzodiazepine Receptor (TSPO) interaction partners

  1. TSPO expression increases ( approximately 9-fold) in rodent-derived macrophages and microglia upon pro-inflammatory stimulation.

  2. Data suggest that up-regulation of translocator protein 18kDa level during neuroinflammation may be an adaptive response mechanism, a way to provide more neurosteroids.

  3. This study confirms TSPO deficiency does not affect viability and bronchial alveolar immune homeostasis.

  4. These results suggested that Wuling powder exhibited an obvious antidepressant effect, which could be due to the improvement of TSPO-mediated mitophagy signaling pathway.

  5. The loss of TSPO in the Central Nervous System did not result in overt developmental defects or phenotypes. The TSPO-/- mouse showed a decrease in glial fibrillary acidic protein (show GFAP ELISA Kits) expression, correlating with a decrease in astrogliosis in response to neural injury during Autoimmune Experimental Encephalomyelitis.

  6. Study reviews the physiological functions of TSPO gene in the mitochondrial permeability transition pore, steroidogenesis and energy metabolism especially in knockout mice. [review]

  7. Study highlights the 3D structure of mTSPO/PBR and in complex with PK11195 providing an important step towards a more detailed understanding of the molecular mechanism of mammalian TSPO/PBR and its interaction with small molecules. [review]

  8. TSPO expression in Sandhoff disease mice is brain region-specific and depends on the age of the animal as disease progresses with the thalamus providing the earliest signal of disease based on TSPO expression and other markers of neurodegeneration

  9. TSPO deficiency does not adversely affect erythropoiesis, heme biosynthesis, bioconversion of ALA to PPIX, and porphyrin-mediated phototoxic cell death.

  10. TSPO can affect mitochondrial energy homeostasis through modulation of fatty acid oxidation, a function that appears to be consistent with high levels of TSPO expression observed in cell types active in lipid storage/metabolism.

Human Peripheral-Type Benzodiazepine Receptor (TSPO) interaction partners

  1. These findings have important implications for understanding the biology of TSPO in activated macrophages and microglia in humans.

  2. TSPO may serve a range of functions that can be viewed as downstream regulatory effects of its primary, evolutionary conserved role in cell metabolism and energy production.

  3. We report for the first time, to our knowledge, the kinetic properties of the novel third-generation TSPO PET ligand (18)F-GE180 in humans: 2TCM4k is the optimal method to quantify the brain uptake, 90 min is the optimal scan length, and the Logan approach could be used to generate parametric maps. Although these control subjects have shown relatively low VT, the methodology presented here forms the basis for quantificati

  4. demonstrate rapid decrease in TSPO binding to the high affinity site induced by exposure to cigarette smoke

  5. Study shows that TSPO's mitochondrial functions include modulation of nuclear gene expression via mitochondrial-nuclear signaling which can suggests whereby TSPO can control several vital cell functions, which has major implications for the whole organism in health and disease.

  6. TSPO is an ancient bacterial receptor/stress sensor that has developed additional interactions, partners, and roles in its mitochondrial outer membrane environment in eukaryotes.

  7. Unlike the strictly mitochondrial localisation of PBR/TSPO, PBR-S (isoform which lacks exon 2) has a punctate distribution throughout the cytosol that co-localises with lysosomes in HeLa, HEK (show EPHA3 ELISA Kits)-293, MDA-MB-231, BJ and U87-MG cells.

  8. [(18)F]PBR102 and [(18)F]PBR111 have distinct metabolic profiles in rat and non-human primates. Radiometabolites contributed to non-specific binding and confounded in vivo brain analysis of [(18)F]PBR102 in rodents; the impact in primates was less pronounced. Both [(18)F]PBR102 and [(18)F]PBR111 are suitable for PET imaging of TSPO in vivo. In vitro metabolite studies can be used to predict in vivo radioligand metabolism

  9. the epigenetic regulation of TSPO

  10. the effects of PK11195 on meningioma were associated the decrease of allopregnanolone biosynthesis, which was mediated by TSPO.

Pig (Porcine) Peripheral-Type Benzodiazepine Receptor (TSPO) interaction partners

  1. PBR mRNA was the more abundant detected form in pig tissues and in warm kidney that underwent ischemia suggesting functional implications of PBR during the renal repair process.

  2. Changes in TSPO expression in kidney regenerating tissue could be important for renal protection and maintenance of kidney function.

Peripheral-Type Benzodiazepine Receptor (TSPO) Antigen Profile

Antigen Summary

Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternatively spliced transcript variants have been reported\; one of the variants lacks an internal exon and is considered non-coding, and the other variants encode the same protein.

Alternative names and synonyms associated with Peripheral-Type Benzodiazepine Receptor (TSPO)

  • peripheral-type benzodiazepine receptor (LOC732875) Elisa Kit
  • peripheral-type benzodiazepine receptor (MAV_3896) Elisa Kit
  • Peripheral-type benzodiazepine receptor (xccb100_2086) Elisa Kit
  • peripheral-type benzodiazepine receptor (Smp_102510) Elisa Kit
  • peripheral-type benzodiazepine receptor (Sros_1911) Elisa Kit
  • peripheral-type benzodiazepine receptor (LOC100136652) Elisa Kit
  • peripheral-type benzodiazepine receptor (LOC100280949) Elisa Kit
  • peripheral-type benzodiazepine receptor (PGTG_16395) Elisa Kit
  • peripheral-type benzodiazepine receptor (PBR) Elisa Kit
  • translocator protein (Tspo) Elisa Kit
  • translocator protein (18kDa) (TSPO) Elisa Kit
  • translocator protein (18kDa) (Tspo) Elisa Kit
  • translocator protein-like (LOC100338710) Elisa Kit
  • BPBS Elisa Kit
  • Bzrp Elisa Kit
  • DBI Elisa Kit
  • IBP Elisa Kit
  • LOC732875 Elisa Kit
  • LOC100136652 Elisa Kit
  • LOC100280949 Elisa Kit
  • MBR Elisa Kit
  • mDRC Elisa Kit
  • PBR Elisa Kit
  • PBS Elisa Kit
  • pk18 Elisa Kit
  • PKBS Elisa Kit
  • PTBR Elisa Kit
  • Ptbzr Elisa Kit
  • PTBZR02 Elisa Kit
  • RATPTBZR02 Elisa Kit
  • TSPO Elisa Kit
  • Tspo1 Elisa Kit

Protein level used designations for TSPO

peripheral-type benzodiazepine receptor , Peripheral-type benzodiazepine receptor , translocator protein , PKBS , benzodiazepine receptor, peripheral , isoquinoline-binding protein , mitochondrial benzodiazepine receptor , Benzodiazepin receptor (peripheral) , PBR , benzodiazepine peripheral binding site , peripheral benzodiazepine receptor , IBP , benzodiazepine receptor (peripheral)

732875 Bombyx mori
4529395 Mycobacterium avium 104
6322197 Xanthomonas campestris pv. campestris str. B100
8346408 Schistosoma mansoni
8665189 Streptosporangium roseum DSM 43021
100136652 Oncorhynchus mykiss
100280949 Zea mays
10528866 Puccinia graminis f. sp. tritici CRL 75-36-700-3
443123 Ovis aries
12257 Mus musculus
24230 Rattus norvegicus
706 Homo sapiens
396592 Sus scrofa
281033 Bos taurus
474475 Canis lupus familiaris
418226 Gallus gallus
100722263 Cavia porcellus
100338710 Oryctolagus cuniculus
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