TSPO Products
(Peripheral-Type Benzodiazepine Receptor (TSPO))
Categories
Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternatively spliced transcript variants have been reported\; one of the variants lacks an internal exon and is considered non-coding, and the other variants encode the same protein. [provided by RefSeq, Feb 2012].
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Featured TSPO Categories
TSPO Antibodies
High quality antibodies with extensive validation data.
TSPO ELISA Kits
Reliable ELISA kits for a wide range of species.
TSPO Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TSPO Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
WB, ELISA, IHC, FACS
Validations
- (1)
- (11)
Cat. No.
ABIN570960
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IP, IF, FACS
Validations
- (6)
Cat. No.
ABIN7127858
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF, FACS
Validations
- (8)
Cat. No.
ABIN185697
Quantity
100 μg
Datasheet
Datasheet
Recommended TSPO ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969216
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958481
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN1572930
Quantity
96 tests
Datasheet
Datasheet
Recommended TSPO Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1323951
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3074824
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3097312
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our TSPO products
: "Synthesis and evaluation of novel potent TSPO PET ligands with 2-phenylpyrazolo[1,5-a]pyrimidin-3-yl acetamide." in: Bioorganic & medicinal chemistry, Vol. 27, Issue 18, pp. 4069-4080, (2019) (PubMed).: "Imaging Macrophage Accumulation in a Murine Model of Chronic Pancreatitis with (125)I-Iodo-DPA-713 SPECT/CT." in: Journal of nuclear medicine : official publication, Society of Nuclear Medicine, Vol. 58, Issue 10, pp. 1685-1690, (2017) (PubMed).
: "ERManI (Endoplasmic Reticulum Class I α-Mannosidase) Is Required for HIV-1 Envelope Glycoprotein Degradation via Endoplasmic Reticulum-associated Protein Degradation Pathway." in: The Journal of biological chemistry, Vol. 290, Issue 36, pp. 22184-92, (2015) (PubMed).
: "Preclinical TSPO Ligand PET to Visualize Human Glioma Xenotransplants: A Preliminary Study." in: PLoS ONE, Vol. 10, Issue 10, pp. e0141659, (2015) (PubMed).
: "The mitochondrial translocator protein, TSPO, inhibits HIV-1 envelope glycoprotein biosynthesis via the endoplasmic reticulum-associated protein degradation pathway." in: Journal of virology, Vol. 88, Issue 6, pp. 3474-84, (2014) (PubMed).
: "Translocator protein 18 kDa negatively regulates inflammation in microglia." in: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, Vol. 9, Issue 3, pp. 424-37, (2014) (PubMed).
: "Targeting mitochondrial 18 kDa translocator protein (TSPO) regulates macrophage cholesterol efflux and lipid phenotype." in: Clinical science (London, England : 1979), Vol. 127, Issue 10, pp. 603-13, (2014) (PubMed).
: "The 18-kDa translocator protein (TSPO) disrupts mammary epithelial morphogenesis and promotes breast cancer cell migration." in: PLoS ONE, Vol. 8, Issue 8, pp. e71258, (2013) (PubMed).
: "Deregulated hepatic metabolism exacerbates impaired testosterone production in Mrp4-deficient mice." in: The Journal of biological chemistry, Vol. 287, Issue 18, pp. 14456-66, (2012) (PubMed).
: "Peripheral benzodiazepine receptor regulates vascular endothelial activations via suppression of the voltage-dependent anion channel-1." in: FEBS letters, Vol. 586, Issue 9, pp. 1349-55, (2012) (PubMed).
Synonyms and alternative names related to TSPO
peripheral-type benzodiazepine receptor (LOC732875), peripheral-type benzodiazepine receptor (MAV_3896), Peripheral-type benzodiazepine receptor (xccb100_2086), putative peripheral-type benzodiazepine receptor (Smp_102510), peripheral-type benzodiazepine receptor (Sros_1911), translocator protein (tspo), translocator protein homolog (LOC100280949), hypothetical protein (PGTG_16395), translocator protein (TSPO), translocator protein (Tspo), BPBS, BZRP, Bzrp, DBI, IBP, LOC732875, LOC100136652, LOC100280949, MBR, mDRC, PBR, PBS, pk18, PKBS, PTBR, Ptbzr, PTBZR02, RATPTBZR02, TSPO, Tspo1Protein level used designations for TSPO
- peripheral-type benzodiazepine receptor
- Peripheral-type benzodiazepine receptor
- translocator protein
- PKBS
- benzodiazepine receptor, peripheral
- isoquinoline-binding protein
- mitochondrial benzodiazepine receptor
- Benzodiazepin receptor (peripheral)
- PBR
- benzodiazepine peripheral binding site
- peripheral benzodiazepine receptor
- IBP
- benzodiazepine receptor (peripheral)
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