Browse our MTA1 Proteins (MTA1)

Full name:
Metastasis Associated 1 Proteins (MTA1)
On are 11 Metastasis Associated 1 (MTA1) Proteins from 5 different suppliers available. Additionally we are shipping MTA1 Antibodies (110) and MTA1 Kits (1) and many more products for this protein. A total of 130 MTA1 products are currently listed.
fj99h01, mta1, wu:fj99h01, zgc:56396
list all proteins Gene Name GeneID UniProt
MTA1 9112 Q13330
MTA1 116870  
Rat MTA1 MTA1 64520 Q62599

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MTA1 Proteins (MTA1) by Origin

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More Proteins for MTA1 Interaction Partners

Human Metastasis Associated 1 (MTA1) interaction partners

  1. Our findings revealed that miR (show MLXIP Proteins)-183 upregulation and MTA1 gene silence significantly repressed the epithelial-mesenchymal transition, migration and invasion of human pancreatic cancer cells.

  2. MTA1 expression was positively correlated with LAT1 (show LAT Proteins) (p=0.013) and CD34 (show CD34 Proteins) (p=0.034) expression, but not with Ki-67 (show MKI67 Proteins) (p=0.078). MTA1 shows promise as a diagnostic and prognostic marker in esophageal cancer, and we anticipate that the gene will also prove to be a good therapeutic target.

  3. In this study, we aimed to analyze the expression of miR (show MLXIP Proteins)-183 and MTA1 in nasopharyngeal carcinoma tissues and cells; explore the role of miR (show MLXIP Proteins)-183 in NPC (show NPC1 Proteins) cell proliferation, invasion, as well as DDP (show TIMM8A Proteins)-induced apoptosis; and investigate the relationship between miR (show MLXIP Proteins)-183 and MTA1 in nasopharyngeal carcinoma cells.

  4. Metastasis-associated protein-1 expression levels in HPV-infected non-small cell lung cancer tissues correlated positively with tumor stage and nodal metastasis.

  5. our studies indicate that Curcumin increases the sensitivity of Paclitaxel-resistant non-small-cell lung cancer cells to Paclitaxel through microRNA-30c-mediated MTA1 reduction. Curcumin might be a potential adjuvant for non-small-cell lung cancer patients during Paclitaxel treatment.

  6. Data show that metastasis associated 1 (MTA1) represses neuronal nitric oxide synthase (nNOS (show NOS1 Proteins)) expression upon oxygen glucose deprivation (OGD (show FGFR1 Proteins))-induced oxidative stress.

  7. Data indicate a positive correlation between metastasis-associated protein 1 (MTA1) and microRNA miR (show MLXIP Proteins)-22, supporting their inhibitory effect on E-cadherin (show CDH1 Proteins) expression.

  8. The MTA1 subunit of the nucleosome remodeling and deacetylase complex can recruit two copies of RBBP4 (show RBBP4 Proteins)/RBBP7 (show RBBP7 Proteins).

  9. Results showed that in the development of colon cancer, MTA1 is linked to certain signal pathways, such as Wnt/Notch/nucleotide excision repair pathways. The findings also suggested that MTA1 demonstrates the closest relationship in a coregulation process with the key molecules AKT1, EP300, CREBBP, SMARCA4, RHOA, and CAD.

  10. elevated expression of MTA1 was significantly correlated with recurrence, and was an independent risk factor for lymph node metastasis in gastric cancer

Mouse (Murine) Metastasis Associated 1 (MTA1) interaction partners

  1. the augmentation of endogenous MTA1 expression during neuronal ischemic injury acts additionally to an endocrinous cascade orchestrating intimate interactions between ERalpha (show ESR1 Proteins) and BCL2 (show BCL2 Proteins) pathways.

  2. Findings highlight MTA1 as a key upstream regulator of prostate tumorigenesis and cancer progression.

  3. Inhibition of MTA1 expression by in vivo siRNA treatment exacerbated the pathology of LPS (show TLR4 Proteins)-induced acute lung injury, by selectively promoting the expression of NF-kappaB (show NFKB1 Proteins)-regulated inflammatory cytokines.

  4. MTA1 was regulated by HIF-1alpha (show HIF1A Proteins) in hypoxia circumstance to suppress osteoblast differentiation.

  5. MTA1 levels were increased in monosodium urate crystal-induced inflammation.

  6. The inhibition of MTA1 gene could depress the growth and metastasis of laryngeal squamous cell carcinoma in nude mice.

  7. Data suggest that nuclear metastasis-associated protein 1 (MTA1) is a good marker for cancer differentiation diagnosis and a potential target for the treatment of cancers.

  8. this study reports the potential signaling events related to up-regulation of metastasis associated protein 1 (Mta1), a master chromatin modifier, during mono-(2-ethylhexyl) phthalate (MEHP)-induced Sertoli cells injury.

  9. MTA1 has an important role in the maintenance of circadian rhythmicity.

  10. the MTA1/NFkappaB/FasL (show FASL Proteins) circuit may serve as an important defensive/repairing mechanism to help to control the germ cell quality after Sertoli cell injury.

Zebrafish Metastasis Associated 1 (MTA1) interaction partners

  1. Findings suggest that Mta3-NuRD complex, inclding component HDAC1 (show HDAC1 Proteins), is essential for the initiation of primitive hematopoiesis.

MTA1 Protein Profile

Protein Summary

This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. It was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with MTA1

  • metastasis associated 1 (MTA1)
  • metastasis associated 1 (mta1)
  • metastasis associated 1 (Mta1)
  • metastasis associated 1 family, member 3 (mta3)
  • fj99h01 protein
  • mta1 protein
  • wu:fj99h01 protein
  • zgc:56396 protein

Protein level used designations for Metastasis Associated 1 Proteins (MTA1)

metastasis associated gene 1 protein , metastasis-associated protein MTA1 , metastasis associated family, member 3 , metastasis-associated protein MTA3

9112 Homo sapiens
447758 Xenopus laevis
429060 Gallus gallus
480450 Canis lupus familiaris
511438 Bos taurus
116870 Mus musculus
64520 Rattus norvegicus
100003254 Danio rerio
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