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Browse our Regulator of Chromosome Condensation 1 Proteins (RCC1)

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Regulator of Chromosome Condensation 1 Proteins (RCC1)
On are 9 Regulator of Chromosome Condensation 1 (RCC1) Proteins from 4 different suppliers available. Additionally we are shipping Regulator of Chromosome Condensation 1 Antibodies (111) and many more products for this protein. A total of 132 Regulator of Chromosome Condensation 1 products are currently listed.
4931417M11Rik, AI326872, BJ1, CG10480, CG18640 (Bj1), CHC1, chc1-a, chc1-b, Dmel\\CG10480, dRCC1, inxs, MGC115703, MGC132085, RanGEF, Rcc1, RCC1-I, sdt, SNHG3-RCC1, wu:fj77f08, xrcc1, zgc:65796, zgc:77114
list all proteins Gene Name GeneID UniProt
RCC1 1104 P18754
RCC1 100088 Q8VE37
Rat RCC1 RCC1 682908  

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Regulator of Chromosome Condensation 1 Proteins (RCC1) by Origin

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More Proteins for Regulator of Chromosome Condensation 1 Interaction Partners

Fruit Fly (Drosophila melanogaster) Regulator of Chromosome Condensation 1 (RCC1) interaction partners

  1. the Bj1 RanGEF promotes Prospero (show PROX1 Proteins) nuclear export and neuroblast self-renewal

  2. crystal structure of a complex of Drosophila RCC1 and the nucleosome core particle at 2.9 A resolution, providing an atomic view of how a chromatin protein interacts with the histone and DNA components of the nucleosome

  3. Data show that dRCC1 is required for nuclear import of nuclear localization signal sequence (NLS (show ALDH1A2 Proteins))-carrying cargo molecules and for cell proliferation and/or survival during germline, eye and wing development and that dRCC1 appears to facilitate apoptosis.

Human Regulator of Chromosome Condensation 1 (RCC1) interaction partners

  1. RCC1 expression enables the proliferation of cells that sustain DNA damage. RCC1-dependent activation of Ran accelerates cell cycle and DNA repair, inhibiting DNA damage-induced cell senescence.

  2. RCC1 expression is frequently lost in poorly differentiated gastric cell lines and gastric carcinoma tissues. Loss of RCC1 expression is correlated with tumor differentiation and depth of invasion.

  3. stress can disrupt the Ran gradients through RCC1-dependent and RCC1-independent mechanisms

  4. PI3Kbeta regulates the nuclear envelope through upstream regulation of RCC1 and Ran

  5. RCC1 facilitates a tight binding between the encephalomyocarditis virus leader and cellular Ran GTPase (show RAN Proteins).

  6. RCC1 can induce bipolar spindle formation. Remarkably, RCC1 beads oscillate within spindles from pole to pole, a behavior that could be converted to a more typical, stable association by the addition of a kinesin together with RCC1.

  7. discovery of the first alpha-N-methyltransferase, which we named N-terminal RCC1 methyltransferase (NRMT (show METTL11A Proteins)).

  8. The authors find that RCC1 uses a conformationally flexible loop region we have termed the switchback loop in addition to its N-terminal tail to bind to the nucleosome.

  9. RanBP3 (show RANBP3 Proteins) associates with the Ran-specific guanine nucleotide exchange factor (show RASGRF1 Proteins), regulator of chromosome condensation 1 (RCC1).

  10. These results indicate that the generation of Ran-GTP (show AK3 Proteins) in the vicinity of chromosomes by RCC1 is important for the fidelity of mitotic spindle assembly in human cells.

Regulator of Chromosome Condensation 1 (RCC1) Protein Profile

Protein Summary

Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo- cytoplasmic transport, mitosis and nuclear-envelope assembly.

Alternative names and synonyms associated with Regulator of Chromosome Condensation 1 (RCC1)

  • regulator of chromosome condensation 1 (rcc1)
  • regulator of chromosome condensation 1 (RCC1)
  • chromosome condensation 1 (rcc1)
  • Bj1 protein (Bj1)
  • N terminal fragment of RCC1; similar to S. cerevisiae SRM1 (YGL097W) guanine nucleotide exchange factor for Gsp1 GTPase involved in assembly of nuclear pore complex; frameshifted (RCC1)
  • regulator of chromosome condensation 1 (rcc1-b)
  • regulator of chromosome condensation 1 (Rcc1)
  • 4931417M11Rik protein
  • AI326872 protein
  • BJ1 protein
  • CG10480 protein
  • CG18640 (Bj1) protein
  • CHC1 protein
  • chc1-a protein
  • chc1-b protein
  • Dmel\\CG10480 protein
  • dRCC1 protein
  • inxs protein
  • MGC115703 protein
  • MGC132085 protein
  • RanGEF protein
  • Rcc1 protein
  • RCC1-I protein
  • sdt protein
  • SNHG3-RCC1 protein
  • wu:fj77f08 protein
  • xrcc1 protein
  • zgc:65796 protein
  • zgc:77114 protein

Protein level used designations for RCC1

chromosome condensation 1 , fj77f08 , regulator of chromosome condensation , regulator of chromosome condensation 1 , RCC1 protein , Bj1-PA , Bj1-PB , Bj1-PC , CG10480-PA , CG10480-PB , CG10480-PC , in excess , side-out , possible fragment of potential guanine nucleotide exchange factor , SNHG3-RCC1 readthrough transcript , cell cycle regulatory protein , guanine nucleotide-releasing protein , chromosome condensation protein 1

406457 Danio rerio
410681 Apis mellifera
720265 Macaca mulatta
100070733 Equus caballus
100568439 Pan troglodytes
100593362 Nomascus leucogenys
397722 Xenopus laevis
38669 Drosophila melanogaster
3641455 Candida albicans SC5314
443810 Xenopus laevis
1104 Homo sapiens
100088 Mus musculus
100621543 Sus scrofa
534142 Bos taurus
682908 Rattus norvegicus
487332 Canis lupus familiaris
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