RCC1 Protein
Quick Overview for RCC1 Protein (ABIN5776891)
Target
See all RCC1 ProteinsProtein Type
Origin
Source
Purity
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Purpose
- RCC1 (RanGEF), Regulator of Chromosome Condensation, Ran Guanine Exchange Factor, human, recombinant, E. coli
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Regulator of Chromosome Condensation 1 (RCC1) (AA 1-421) protein (GST tag)
RCC1 Origin: Human Host: Wheat germ Recombinant ELISA, AP, AA, WB
Regulator of Chromosome Condensation 1 (RCC1) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)RCC1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Supplied in 20 mM HEPES pH 7.650 mM NaCl and 2 mM DTE
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Handling Advice
- Please centrifuge briefly before opening (volume ≤2 ml).,avoid freeze/thaw cycles
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Storage
- -80 °C
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Storage Comment
- store at -80 °C avoid freeze/thaw cycles
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Expiry Date
- 12 months
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- RCC1 (Regulator of Chromosome Condensation 1 (RCC1))
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Alternative Name
- RCC1 (RanGEF)
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Background
- RCC1 (Regulator of Chromosome Condensation, a β propeller chromatin-bound protein) catalyzes guanine nucleotide exchange of the Ras-related nuclear protein Ran. RCC1 is the guanine nucleotide exchange factor (GEF) for Ran which induces exchange between the bound GDP and cellular GTP. Genetic studies have suggested that RCC1 may be involved in sensing the replication state of DNA and controlling the activation of Cdc2/cyclin B protein kinase through Ran.
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Molecular Weight
- 44.97 kDa (421 amino acids)
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Pathways
- Chromatin Binding, Protein targeting to Nucleus
Target
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