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Browse our SF3B1 Proteins (SF3B1)

Full name:
Splicing Factor 3b, Subunit 1, 155kDa Proteins (SF3B1)
On are 3 Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) Proteins from 2 different suppliers available. Additionally we are shipping SF3B1 Antibodies (67) and SF3B1 Kits (1) and many more products for this protein. A total of 79 SF3B1 products are currently listed.
155kDa, 2810001M05Rik, AA409119, Hsh155, MDS, PRP10, PRPF10, sap155, SF3B1, SF3b155, TA-8, Targ4, wu:fb99f09
list all proteins Gene Name GeneID UniProt
SF3B1 81898  
Rat SF3B1 SF3B1 84486  
SF3B1 23451 O75533

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SF3B1 Proteins (SF3B1) by Origin

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More Proteins for SF3B1 Interaction Partners

Zebrafish Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) interaction partners

  1. Data indicate that splicing factor 3b (show SF3B14 Proteins), subunit 1 (sf3b1) mutation causes aberrant splicing of sf3b1 resulting in functional and predicted non-functional transcripts and a 90% reduction in full-length Sf3b1 protein.

Mouse (Murine) Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) interaction partners

  1. myocardial hypoxia actuates fructose metabolism in human and mouse models of pathological cardiac hypertrophy through hypoxia-inducible factor 1alpha (HIF1alpha (show HIF1A Proteins)) activation of SF3B1 and SF3B1-mediated splice switching of KHK (show KHK Proteins)-A to KHK (show KHK Proteins)-C

  2. Sf3b1 isrequired for the blastocyst formation.

  3. SF3B1 plays an important role in the regulation of hematopoietic stem cells, whereas SF3B1 haploinsufficiency itself is not associated with the myelodysplastic syndrome phenotype with ring sideroblasts.

  4. The level of Sf3b1 expression is critical for the proliferative capacity of hematopoietic stem cells. Depletion of Sf3b1 impairs proliferative capacity of hematopoietic stem cells but is not sufficient to induce myelodysplasia.

  5. SF3B1 haploinsufficiency leads to formation of ring sideroblasts in myelodysplastic syndromes.

  6. the active spliceosome, containing SAP155 phosphorylated by DYRKIA, performs pre-mRNA splicing in spermatogonia during testicular development

  7. active spliceosome, containing phosphorylated SAP155, performs pre-mRNA splicing on chromatin concomitant with transcription during testicular development.

  8. Sf3b1 and Polycomb (show CBX2 Proteins) group (PcG) proteins interaction is essential for true PcG-mediated repression of Hox (show MSH2 Proteins) genes.

Human Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) interaction partners

  1. Mutations in ASXL1 (show ASXL1 Proteins), U2AF1 (show U2AF1 Proteins), and SF3B1 (show SF3B2 Proteins) are common in Chinese patients with myelodysplastic syndromes.

  2. The clinical impact of small subclones harboring NOTCH1 (show NOTCH1 Proteins), SF3B1 (show SF3B2 Proteins), or BIRC3 (show BIRC3 Proteins) mutations in chronic lymphocytic leukemia patients appears to be less pronounced than that of small TP53 (show TP53 Proteins) mutated subclones.

  3. No relationship was observed between IGHV mutational status and SF3B1 (show SF3B2 Proteins) mutationfa

  4. The genotype frequencies of SF3B1 (show SF3B2 Proteins) SNP rs788018 were TT 13.2%, TC 39.6%, and CC 47.2% in Childhood AML (show RUNX1 Proteins) patients.

  5. The finding of this study showed that an SF3B1 (show SF3B2 Proteins) or EIF1AX (show EIF1AX Proteins) mutation is present in a substantial subset of primary LMNs underscores that these tumors genetically resemble uveal melanoma and are different from cutaneous melanoma at the genetic level.

  6. SF3B1 (show SF3B2 Proteins)-mutated myelodysplastic syndrome with ring sideroblasts harbors more severe iron overload and corresponding over-erythropoiesis.

  7. studies reveal new mechanistic insight into SF3B1 (show SF3B2 Proteins) as a principal player in the spliceosome and as a target of inhibitor compounds

  8. SF3B1 (show SF3B2 Proteins) - novel candidate genes validated in a large case-control sample of schizophrenia.

  9. In uveal melanoma, the SF3B1 (show SF3B2 Proteins)(R625/K666) mutation results in deregulated splicing at a subset of junctions, mostly by the use of alternative 3'ss.

  10. Data show that tet methylcytosine dioxygenase 2 TET2, isocitrate dehydrogenases 1/2 IDH1 (show IDH1 Proteins)/IDH2 (show IDH2 Proteins), serine/arginine-rich splicing factor 2 SRSF2 (show SRSF2 Proteins), splicing factor 3b subunit 1 SF3B1, and ras proteins (KRAS/NRAS) are not conserved in dog mast Cell tumors.

SF3B1 Protein Profile

Protein Summary

This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms.

Alternative names and synonyms associated with SF3B1

  • splicing factor 3b, subunit 1, 155kDa (SF3B1)
  • splicing factor 3b, subunit 1, 155kDa (sf3b1)
  • splicing factor 3b, subunit 1 (sf3b1)
  • splicing factor 3b, subunit 1 (Sf3b1)
  • 155kDa protein
  • 2810001M05Rik protein
  • AA409119 protein
  • Hsh155 protein
  • MDS protein
  • PRP10 protein
  • PRPF10 protein
  • sap155 protein
  • SF3B1 protein
  • SF3b155 protein
  • TA-8 protein
  • Targ4 protein
  • wu:fb99f09 protein

Protein level used designations for SF3B1

splicing factor 3b, subunit 1, 155kDa , splicing factor 3B subunit 1 , splicing factor 3B subunit 1-like , tst , SAP 155 , pre-mRNA-splicing factor SF3b 155 kDa subunit , spliceosome-associated protein 155 , splicing factor 3b, subunit 1, 155 kDa , transforming growth factor alpha regulated gene 4 , splicing factor 3b, subunit 1, 155kD , 146 kDa nuclear protein , SF3b155 , pre-mRNA processing 10 , pre-mRNA splicing factor SF3b, 155 kDa subunit

459850 Pan troglodytes
510177 Bos taurus
697773 Macaca mulatta
100022236 Monodelphis domestica
100070506 Equus caballus
100413687 Callithrix jacchus
100477819 Ailuropoda melanoleuca
100547422 Meleagris gallopavo
100559157 Anolis carolinensis
100604147 Nomascus leucogenys
446117 Danio rerio
81898 Mus musculus
84486 Rattus norvegicus
399336 Xenopus laevis
424056 Gallus gallus
23451 Homo sapiens
488456 Canis lupus familiaris
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