SF3B1 Products
(Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))
Categories
This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
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Featured SF3B1 Categories
SF3B1 Antibodies
High quality antibodies with extensive validation data.
SF3B1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SF3B1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
Cat. No.
ABIN7127805
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (4)
Cat. No.
ABIN657676
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (4)
Cat. No.
ABIN7270543
Quantity
100 μL
Datasheet
Datasheet
Recommended SF3B1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3095345
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3136987
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7420513
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our SF3B1 products
: "Depletion of the MFAP1/SPP381 Splicing Factor Causes R-Loop-Independent Genome Instability." in: Cell reports, Vol. 28, Issue 6, pp. 1551-1563.e7, (2020) (PubMed).: "PHF5A Epigenetically Inhibits Apoptosis to Promote Breast Cancer Progression." in: Cancer research, Vol. 78, Issue 12, pp. 3190-3206, (2018) (PubMed).
Synonyms and alternative names related to SF3B1
splicing factor 3b subunit 2 (SF3B2), splicing factor 3b subunit 1 (SF3B1), splicing factor 3b, subunit 1 (Sf3b1), splicing factor 3b subunit 1 S homeolog (sf3b1.S), splicing factor 3b subunit 1 (sf3b1), splicing factor 3b, subunit 1 (sf3b1), splicing factor 3b subunit 1 (Sf3b1), 155kDa, 2810001M05Rik, AA409119, Cus1, Hsh155, hsh155, MDS, PRP10, Prp10, prp10, PRPF10, prpf10, SAP145, SAP155, sap155, Sap155, SF3b1, SF3B1, SF3B145, SF3b150, SF3b155, TA-8, Targ4, wu:fb99f09Protein level used designations for SF3B1
- SAP 145
- pre-mRNA splicing factor SF3b 145 kDa subunit
- pre-mRNA-splicing factor SF3b 145 kDa subunit
- spliceosome associated protein 145
- spliceosome-associated protein 145
- splicing factor 3B subunit 2
- SAP 155
- pre-mRNA processing 10
- pre-mRNA splicing factor SF3b, 155 kDa subunit
- spliceosome-associated protein 155
- splicing factor 3B subunit 1
- pre-mRNA-splicing factor SF3b 155 kDa subunit
- splicing factor 3b, subunit 1, 155 kDa
- transforming growth factor alpha regulated gene 4
- 146 kDa nuclear protein
- SF3b155
- splicing factor 3b, subunit 1, 155kDa
- splicing factor 3B subunit 1-like
- splicing factor 3b, subunit 1, 155kD
- tst
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