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Browse our anti-CD59 (CD59) Antibodies

Full name:
anti-CD59 Antibodies (CD59)
On www.antibodies-online.com are 391 CD59 Antibodies from 27 different suppliers available. Additionally we are shipping CD59 Kits (40) and CD59 Proteins (34) and many more products for this protein. A total of 475 CD59 products are currently listed.
Synonyms:
1F5, 16.3A5, AA987121, Cd59, Cd59a, Cd59b, EJ16, EJ30, EL32, G344, HRF-20, HRF20, MAC-IP, MACIF, MACIP, MEM43, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, p18-20, protectin

Most Popular Reactivities for anti-CD59 (CD59) Antibodies

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anti-Human CD59 Antibodies:

anti-Rat (Rattus) CD59 Antibodies:

anti-Mouse (Murine) CD59 Antibodies:

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Top referenced anti-CD59 Antibodies

  1. Human Monoclonal CD59 Primary Antibody for FACS, IHC (p) - ABIN118752 : Cebecauer, Cerný, Horejsí: Incorporation of leucocyte GPI-anchored proteins and protein tyrosine kinases into lipid-rich membrane domains of COS-7 cells. in Biochemical and biophysical research communications 1998 (PubMed)
    Show all 12 references for ABIN118752

  2. Human Monoclonal CD59 Primary Antibody for FACS, IHC (fro) - ABIN119472 : Davies, Simmons, Hale, Harrison, Tighe, Lachmann, Waldmann: CD59, an LY-6-like protein expressed in human lymphoid cells, regulates the action of the complement membrane attack complex on homologous cells. in The Journal of experimental medicine 1989 (PubMed)
    Show all 6 references for ABIN119472

  3. Human Monoclonal CD59 Primary Antibody for IHC (fro), FACS - ABIN1106481 : Kinoshita, Inoue, Takeda: Defective glycosyl phosphatidylinositol anchor synthesis and paroxysmal nocturnal hemoglobinuria. in Advances in immunology 1996 (PubMed)
    Show all 6 references for ABIN1106481

  4. Human Monoclonal CD59 Primary Antibody for EIA, FACS - ABIN118747 : Tandon, Yan, Morgan, Weetman: Expression and function of multiple regulators of complement activation in autoimmune thyroid disease. in Immunology 1994 (PubMed)
    Show all 4 references for ABIN118747

  5. Human Monoclonal CD59 Primary Antibody for FACS - ABIN118753 : Horejsí, Angelisová, Bazil, Kristofová, Stoyanov, Stefanová, Hausner, Vosecký, Hilgert et al.: Monoclonal antibodies against human leucocyte antigens. II. Antibodies against CD45 (T200), CD3 (T3), CD43, CD10 (CALLA), transferrin receptor (T9), a novel broadly expressed 18-kDa antigen (MEM-43) ... in Folia biologica 1988 (PubMed)
    Show all 4 references for ABIN118753

  6. Human Monoclonal CD59 Primary Antibody for FACS - ABIN119474 : Walsh, Tone, Waldmann: Transfection of human CD59 complementary DNA into rat cells confers resistance to human complement. in European journal of immunology 1991 (PubMed)
    Show all 3 references for ABIN119474

  7. Human Monoclonal CD59 Primary Antibody for FACS, IP - ABIN1449269 : Okada, Harada, Fujita, Okada: A novel membrane glycoprotein capable of inhibiting membrane attack by homologous complement. in International immunology 1991 (PubMed)
    Show all 2 references for ABIN1449269

  8. Human Monoclonal CD59 Primary Antibody for Func, FACS - ABIN118751 : Stefanová, Horejsí: Association of the CD59 and CD55 cell surface glycoproteins with other membrane molecules. in Journal of immunology (Baltimore, Md. : 1950) 1991 (PubMed)
    Show all 2 references for ABIN118751

  9. Human Monoclonal CD59 Primary Antibody for ICC, FACS - ABIN1098134 : Alegretti, Mucenic, Merzoni, Faulhaber, Silla, Xavier: Expression of CD55 and CD59 on peripheral blood cells from systemic lupus erythematosus (SLE) patients. in Cellular immunology 2010 (PubMed)
    Show all 2 references for ABIN1098134

More Antibodies against CD59 Interaction Partners

Human CD59 interaction partners

  1. Urinary CD59 and alpha-1 antitrypsin (show SERPINA1 Antibodies) are significantly altered in hypertensive patients developing albuminuria.

  2. levels of CSF (show CSF2 Antibodies) CD59 in neuromyelitis optica and multiple sclerosis

  3. Increased internalization of endothelial CD59 in intermittent hypoxia appeared to be cholesterol-dependent and was reversed by statins in a CD59-dependent manner.

  4. Low urine CD59 expression is associated with clear cell renal cell carcinoma (show MOK Antibodies).

  5. Decreased CD59 expression in threatened miscarriage at late gestational ages leads to additional activation of a maternal immune response and serves as a possible predictor for premature birth.

  6. Data show that the palmitoylation mutation of linker for activation of T cells (LAT (show LAT Antibodies))attenuated the signal transduction induced by glycosylphosphatidylinositol-anchored CD59 antigen in T cells.

  7. After blockage of CD59 function, the reactive Abs, regardless of their neutralizing activities, significantly enhanced specific ADCML of HIV-1 virions

  8. Genetic risk at the CFH (show CFH Antibodies)-to-F13B (show F13B Antibodies) locus was associated with higher levels of complement activation at the human macular RPE (show RPE Antibodies)-choroid interface, as was cigarette smoking. Levels of CRP (show CRP Antibodies) were substantially elevated in risk donors with smoking history.

  9. A primary homozygous Cys89Tyr CD59 deficiency in humans resulted in the amino acid substitution p.Cys89Tyr with ensuing failure of proper localization of the CD59 protein to the cell surface. (Review)

  10. Increased CD59 protein expression is associated with the outcome of patients with diffuse large B-cell lymphoma treated with R-CHOP (show DDIT3 Antibodies) antineoplastic protocol.

Pig (Porcine) CD59 interaction partners

  1. Data demonstrate that the resistance of neonatal porcine Sertoli cells to human xenoantibody and complement-mediated lysis is associated with low expression of xenoantigen alpha-Gal and high production of the complement inhibitors clusterin (show CLU Antibodies) and CD59.

Mouse (Murine) CD59 interaction partners

  1. Varicella-zoster virus infection upregulates host CD59 expression in a tissue-specific manner.

  2. This study support a role of Cd59a in controlling the innate immune status of the RPE (show RPE Antibodies)-choroidal complex and emphasizes the particular vulnerability of this ocular compartment to the dysregulation of alternative complement pathway during aging

  3. results implicate CD59 as an important modulator of the immune response in NMO, and provide a novel animal model of NMO that closely recapitulates human NMO pathology.

  4. Soluble forms of CD59 (sCD59) have been investigated in mouse laser-induced choroidal neovascularization, a model for "wet" age related macular degeneration.

  5. both CD59 and C-PC could inhibit the progress of atherosclerosis, and the anti-atherosclerotic effects of C-PC might be fulfilled by promoting CD59 expression, preventing smooth muscle cell proliferation and the apoptosis of endothelial cells

  6. CD59a inhibits systemic autoimmunity in MRL/lpr (show FAS Antibodies) mice through a complement-independent mechanism.

  7. While the connection between CFH (show CFH Antibodies) deficiency and failure to upregulate CD59a remains unknown, these results suggest that expression of CD59 is tissue-specific and that neuroretinal regulation depends on CFH (show CFH Antibodies).

  8. Actively immunized experimental autoimmune myasthenia gravis mice deficient in either CD55 or CD59 showed significant differences in adaptive immune responses and worsened disease outcome associated with increased levels of serum cytokines, modified production of acetylcholine receptor antibodies, and more complement deposition at the neuromuscular junction.

  9. HBx can up-regulate CD59 and Crry (show CR1L Antibodies) expression in podocytes through activating the P38 (show CRK Antibodies) pathway.

  10. CD59 has a role in growth of the choroidal neovascular complex in mice

CD59 Antigen Profile

Antigen Summary

This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.

Alternative names and synonyms associated with CD59

  • CD59 molecule, complement regulatory protein (CD59) antibody
  • CD59 molecule, complement regulatory protein (Cd59) antibody
  • CD59a antigen (Cd59a) antibody
  • CD59b antigen (Cd59b) antibody
  • 1F5 antibody
  • 16.3A5 antibody
  • AA987121 antibody
  • Cd59 antibody
  • Cd59a antibody
  • Cd59b antibody
  • EJ16 antibody
  • EJ30 antibody
  • EL32 antibody
  • G344 antibody
  • HRF-20 antibody
  • HRF20 antibody
  • MAC-IP antibody
  • MACIF antibody
  • MACIP antibody
  • MEM43 antibody
  • MIC11 antibody
  • MIN1 antibody
  • MIN2 antibody
  • MIN3 antibody
  • MIRL antibody
  • MSK21 antibody
  • p18-20 antibody
  • protectin antibody

Protein level used designations for anti-CD59 (CD59) Antibodies

1F5 antigen , 20 kDa homologous restriction factor , CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344) , CD59 glycoprotein , Ly-6-like protein , MEM43 antigen , T cell-activating protein , human leukocyte antigen MIC11 , lymphocytic antigen CD59/MEM43 , membrane attack complex (MAC) inhibition factor , membrane attack complex inhibition factor , membrane inhibitor of reactive lysis , protectin , surface anitgen recognized by monoclonal antibody 16.3A5 , MAC-IP , MAC-inhibitory protein , MACIF , CD59 antigen , CD59b moleucle, complement regulatory protein , Cb59b molecule , CD59 homolog , CD59A glycoprotein , CD59B glycoprotein

GENE ID SPECIES
966 Homo sapiens
397347 Sus scrofa
25407 Rattus norvegicus
739046 Pan troglodytes
100009459 Oryctolagus cuniculus
101102670 Ovis aries
100173870 Pongo abelii
12509 Mus musculus
333883 Mus musculus
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