Browse our anti-Glutaminase 2 (Liver, Mitochondrial) (GLS2) Antibodies

Full name:
anti-Glutaminase 2 (Liver, Mitochondrial) Antibodies (GLS2)
On www.antibodies-online.com are 64 Glutaminase 2 (Liver, Mitochondrial) (GLS2) Antibodies from 13 different suppliers available. Additionally we are shipping Glutaminase 2 (Liver, Mitochondrial) Kits (7) and Glutaminase 2 (Liver, Mitochondrial) Proteins (5) and many more products for this protein. A total of 83 Glutaminase 2 (Liver, Mitochondrial) products are currently listed.
Synonyms:
A330074B06Rik, AI195532, Ga, GLS, hLGA, Lga, si:ch211-216k22.10

Most Popular Reactivities for anti-Glutaminase 2 (Liver, Mitochondrial) (GLS2) Antibodies

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All available anti-Glutaminase 2 (Liver, Mitochondrial) Antibodies

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Top referenced anti-Glutaminase 2 (Liver, Mitochondrial) Antibodies

  1. Cow (Bovine) Polyclonal GLS2 Primary Antibody for IHC, WB - ABIN2781319 : Toriumi, Mouri, Narusawa, Aoyama, Ikawa, Lu, Nagai, Mamiya, Kim, Nabeshima: Prenatal NMDA receptor antagonism impaired proliferation of neuronal progenitor, leading to fewer glutamatergic neurons in the prefrontal cortex. in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2012 (PubMed)

  2. Human Polyclonal GLS2 Primary Antibody for ELISA, ICC - ABIN4314469 : Gross, Demo, Dennison, Chen, Chernov-Rogan, Goyal, Janes, Laidig, Lewis, Li, Mackinnon, Parlati, Rodriguez, Shwonek, Sjogren, Stanton, Wang, Yang, Zhao, Bennett: Antitumor activity of the glutaminase inhibitor CB-839 in triple-negative breast cancer. in Molecular cancer therapeutics 2014 (PubMed)

  3. Human Polyclonal GLS2 Primary Antibody for IHC (p), WB - ABIN652216 : Shroff, Eberlin, Dang, Gouw, Gabay, Adam, Bellovin, Tran, Philbrick, Garcia-Ocana, Casey, Li, Dang, Zare, Felsher: MYC oncogene overexpression drives renal cell carcinoma in a mouse model through glutamine metabolism. in Proceedings of the National Academy of Sciences of the United States of America 2015 (PubMed)

More Antibodies against Glutaminase 2 (Liver, Mitochondrial) Interaction Partners

Human Glutaminase 2 (Liver, Mitochondrial) (GLS2) interaction partners

  1. This study assessed the relation of GLS2 downregulation in glioblastoma cells to its methylation and TP53 (show TP53 Antibodies) status. Aberrant methylation of CpG islands, appear to contribute to silencing of GLS2 in glioblastoma cells by a mechanism bypassing TP53 (show TP53 Antibodies) mutations.

  2. Non-glutaminolysis function of GLS2 inhibits migration and invasion of hepatocellular carcinoma cells by repressing the epithelial-mesenchymal transition via the Dicer (show DICER1 Antibodies)-miR (show MLXIP Antibodies)-34a-Snail (show SNAI1 Antibodies) axis.

  3. observe that while miR (show MLXIP Antibodies)-23 is capable of down-regulating the shortened KGA (show GLS Antibodies) 3'UTR (show UTS2R Antibodies), it has only minor impact on the full-length KGA (show GLS Antibodies) 3'UTR (show UTS2R Antibodies), demonstrating that additional potent negative regulation of GLS (show GLS Antibodies) expression exists beyond this single microRNA targeting site

  4. the crystal structure of full-length KGA (show GLS Antibodies) and present a small-angle X-ray scattering model for full-length GLS2. These structures explain these proteins' compromised ability to assemble into catalytically active supra-tetrameric filaments, as previously shown for GAC (show GLS Antibodies).

  5. Cox (show COX8A Antibodies) multivariate regression analysis demonstrated that DUOX1 (show DUOX1 Antibodies), GLS2, FBP1 (show FBP1 Antibodies) and age were independent risk factors for the prognosis of HCC (show FAM126A Antibodies) patients after surgery

  6. As a p53 target, GLS2 mediates p53's function in metastasis suppression through inhibiting Rac1.

  7. IDO (show IDO1 Antibodies), through GCN2 (show EIF2AK4 Antibodies) kinase activation, downregulates the levels of TCRcomplex tchain and cMyc (show MYC Antibodies), resulting in the suppression of Tcell proliferation and a reduction in the levels of LDHA (show LDHA Antibodies) and GLS2

  8. GABAergic neurons and astrocytes express Gls (show GLS Antibodies) and Gls2 isoenzymes in nucleus and mitochondria, in addition to glutamatergic neurons

  9. Phosphate-activated glutaminase and GAD65 (show GAD2 Antibodies)/67 concentrations are compared in Alzheimer's disease cerebellum versus normal cerebellum controls

  10. GLS2 expression is significantly decreased in hepatocellular carcinoma.

Mouse (Murine) Glutaminase 2 (Liver, Mitochondrial) (GLS2) interaction partners

  1. Gls2 expression is regulated by the dietary protein/carbohydrate ratio. This effect was not observed in Ppara (show PPARA Antibodies)-null mice.

  2. Study demonstrated expression of alternative transcripts of the mammalian Gls2 gene. Transcriptional mechanisms giving rise to GLS2 variants and isolation of novel GLS2 transcripts in human, rat and mouse are presented.

  3. Phosphate-activated glutaminase (GLS2) is a p53 (show TP53 Antibodies)-inducible regulator of glutamine (show GFPT1 Antibodies) metabolism and reactive oxygen species

Glutaminase 2 (Liver, Mitochondrial) (GLS2) Antigen Profile

Antigen Summary

The protein encoded by this gene is a mitochondrial phosphate-activated glutaminase that catalyzes the hydrolysis of glutamine to stoichiometric amounts of glutamate and ammonia. This protein is functionally similar to the kidney glutaminase but is a little smaller in size. Originally thought to be liver-specific, this protein has been found in other tissues as well. At least one transcribed pseudogene has been found for this gene.

Alternative names and synonyms associated with Glutaminase 2 (Liver, Mitochondrial) (GLS2)

  • glutaminase 2 (glsA2) antibody
  • glutaminase 2 (LOAG_03311) antibody
  • glutaminase 2 (liver, mitochondrial) (gls2) antibody
  • glutaminase 2 (liver, mitochondrial) (GLS2) antibody
  • glutaminase 2 (liver, mitochondrial) (Gls2) antibody
  • A330074B06Rik antibody
  • AI195532 antibody
  • Ga antibody
  • GLS antibody
  • hLGA antibody
  • Lga antibody
  • si:ch211-216k22.10 antibody

Protein level used designations for GLS2

glutaminase 2 , L-glutamine amidohydrolase , breast cell glutaminase , glutaminase I , glutaminase liver isoform, mitochondrial , phosphate-activated glutaminase , phosphate-dependent glutaminase , L-glutaminase , liver mitochondrial glutaminase , GLS

GENE ID SPECIES
8710836 Citrobacter rodentium ICC168
9940699 Loa loa
100006303 Danio rerio
27165 Homo sapiens
100686499 Canis lupus familiaris
539561 Bos taurus
216456 Mus musculus
192268 Rattus norvegicus
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